Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Tara M. DeSilva"'
Autor:
Gabrielle M. Mey, Kirsten S. Evonuk, McKenzie K. Chappell, Laura M. Wolfe, Rupesh Singh, Julia C. Batoki, Minzhong Yu, Neal S. Peachey, Bela Anand-Apte, Robert Bermel, Daniel Ontaneda, Kunio Nakamura, Kedar R. Mahajan, Tara M. DeSilva
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-18 (2022)
Abstract Thalamic volume is associated with clinical disability in multiple sclerosis (MS) and is vulnerable to secondary neurodegeneration due to its extensive connectivity throughout the central nervous system (CNS). Using a model of autoimmune dem
Externí odkaz:
https://doaj.org/article/d1f51e11e09742c58a6739f3748c0f61
Autor:
Gabrielle M. Mey, Tara M. DeSilva
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Neurodegeneration occurs early in the multiple sclerosis (MS) disease course and is an important driver of permanent disability. Current immunomodulatory therapies do not directly target neuronal health; thus, there is a critical need to develop neur
Externí odkaz:
https://doaj.org/article/bb2c0501bdf54bb0a0fb12d9a31bffdc
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 37 (2022)
We asked whether hyperoxia might induce hypomyelination of the corpus callosum, clinically described as periventricular leukomalacia (PVL) of the severely preterm infant. Mouse pups and their nursing dams were placed in 80% oxygen from P4-P8, then re
Externí odkaz:
https://doaj.org/article/516e198bc24346d0b0ecfc2ee8abf5a9
Autor:
Gabrielle M. Mey, Kirsten S. Evonuk, McKenzie K. Chappell, Laura M. Wolfe, Rupesh Singh, Julia C. Batoki, Minzhong Yu, Neal S. Peachey, Bela Anand‑Apte, Robert Bermel, Daniel Ontaneda, Kunio Nakamura, Kedar R. Mahajan, Tara M. DeSilva
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/5fa399d81b7a47ffb4894f89249b8d0f
Autor:
Ashley D. Nemes-Baran, Tara M. DeSilva
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100403- (2021)
Summary: Microglia have emerged as essential regulators of neurodevelopment by phagocytosing synapses. Recently, we showed that microglia engulf viable oligodendrocyte progenitor cells (OPCs) during development to facilitate myelination. Here, we des
Externí odkaz:
https://doaj.org/article/06301c28e28b44db813ca001b0b88a62
Publikováno v:
Neurology Research International, Vol 2012 (2012)
Externí odkaz:
https://doaj.org/article/7883159cc0694bf390ca39625235caf4
Publikováno v:
The FEBS Journal. 289:2110-2127
Emerging roles for microglia in modifying normal brain development continue to provide new perspectives on the functions of this resident immune cell in the brain. While the molecular underpinnings driving microglia's position in regulating developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5cd6e9fbf7b8c7a9587fbdfa57dd8a3
https://doi.org/10.1111/febs.16190
https://doi.org/10.1111/febs.16190
Autor:
Gabrielle M. Mey, Tara M. DeSilva
Publikováno v:
Neuron. 110(19)
In cancer and cardiovascular disease, endothelial cells can transform into mesenchymal cells (EndoMT), affecting disease onset and progression. In this issue of Neuron, Sun et al. (2022) demonstrate how EndoMT triggers breakdown of the blood-CNS barr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3150e557a7bbfcba48eecc3a80d0981
https://pubmed.ncbi.nlm.nih.gov/35961320
https://pubmed.ncbi.nlm.nih.gov/35961320
Autor:
Tara M DeSilva
Publikováno v:
Open Access Government. 37:136-137
Remyelinating versus neuroprotective therapies for multiple sclerosis Reducing clinical relapses and improving quality of life is at the heart of MS treatment; here, Tara M. DeSilva explores the benefits of remyelinating versus neuroprotective therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d29b3234e5ac95f9449fd841e80d7955
https://doi.org/10.56367/oag-037-10382
https://doi.org/10.56367/oag-037-10382
Publikováno v:
WIREs mechanisms of diseaseFURTHER READINGREFERENCES.
Axonal loss in multiple sclerosis (MS) is a key component of disease progression and permanent neurologic disability. MS is a heterogeneous demyelinating and neurodegenerative disease of the central nervous system (CNS) with varying presentation, dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaebb387254d902b1df2d70c8b057274
https://pubmed.ncbi.nlm.nih.gov/35948371
https://pubmed.ncbi.nlm.nih.gov/35948371