Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tara L Mader"'
Autor:
Susan A Novotny, Tara L Mader, Angela G Greising, Angela S Lin, Robert E Guldberg, Gordon L Warren, Dawn A Lowe
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104339 (2014)
The objective of the study was to determine if low intensity, high frequency vibration training impacted the musculoskeletal system in a mouse model of Duchenne muscular dystrophy, relative to healthy mice. Three-week old wildtype (n = 26) and mdx mi
Externí odkaz:
https://doaj.org/article/27be7dc7a52f4432869ab285ba7a0b11
Autor:
Dawn A. Lowe, Sira Karvinen, Christine A. Cabelka, Hanna Kaarina Juppi, Eija K. Laakkonen, Gengyun Le, Tara L. Mader
Publikováno v:
Exp Gerontol
Background Menopause leads to estradiol (E2) deficiency that is associated with decreases in muscle mass and strength. Here we studied the effect of E2 deficiency on miR-signaling that targets apoptotic pathways. Methods C57BL6 mice were divided into
Autor:
Sarah M. Greising, Gordon L. Warren, Dawn A. Lowe, Tara L. Mader, Sunny Sun Kin Chan, Gengyun Le, Michael Kyba, Susan A. Novotny
Publikováno v:
The Journal of Physiology. 596:4665-4680
Key points The female hormone oestrogen may protect muscle from injury by reducing inflammation but this is debatable. In this study, the inflammatory response of injured muscle from oestrogen-replete mice was comprehensively compared to that from oe
Autor:
Christine A. Cabelka, Espen E. Spangenburg, Dawn A. Lowe, Brittany C. Collins, Tara L. Mader, Melissa R. Iñigo
Publikováno v:
Journal of Applied Physiology. 124:980-992
Estradiol deficiency in females can result in skeletal muscle strength loss, and treatment with estradiol mitigates the loss. There are three primary estrogen receptors (ERs), and estradiol elicits effects through these receptors in various tissues.
Autor:
Gengyun, Le, Susan A, Novotny, Tara L, Mader, Sarah M, Greising, Sunny S K, Chan, Michael, Kyba, Dawn A, Lowe, Gordon L, Warren
KEY POINTS: The female hormone oestrogen may protect muscle from injury by reducing inflammation but this is debatable. In this study, the inflammatory response of injured muscle from oestrogen‐replete mice was comprehensively compared to that from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::77e8cb3beb8d8d4b55e3e99324033713
https://europepmc.org/articles/PMC6166067/
https://europepmc.org/articles/PMC6166067/
Autor:
Allison M. Kosir, Angela G. Greising, Tara L. Mader, Dawn A. Lowe, Kristen A. Baltgalvis, Susan A. Novotny
Publikováno v:
Medicine & Science in Sports & Exercise. 47:1177-1187
The primary objective of this study was to determine whether strength loss and recovery after eccentric contractions are impaired in healthy and dystrophic female mice with low levels of ovarian hormones.Female C57BL/6 (wild-type) or mdx mice were ra
Autor:
James M. Ervasti, Glen B. Banks, Dawn A. Lowe, Melissa K. Gardner, Michael D. Eckhoff, Joseph J. Belanto, Dana M. Strandjord, Tara L. Mader
Publikováno v:
Proceedings of the National Academy of Sciences. 111:5723-5728
Dystrophin and utrophin are highly similar proteins that both link cortical actin filaments with a complex of sarcolemmal glycoproteins, yet localize to different subcellular domains within normal muscle cells. In mdx mice and Duchenne muscular dystr
Autor:
Robert W. Arpke, Akira Toyama, Nardina Nash, Tara L. Mader, Dawn A. Lowe, Radbod Darabi, Michael Kyba, Yu Zhang, Cara lin Lonetree, Rita C.R. Perlingeiro
Publikováno v:
Stem Cells. 31:1611-1620
Transplantation of a myogenic cell population into an immunodeficient recipient is an excellent way of assessing the in vivo muscle-generating capacity of that cell population. To facilitate both allogeneic and xenogeneic transplantations of muscle-f
Autor:
Gregg G. Gundersen, Joseph J. Belanto, Tara L. Mader, James M. Ervasti, Preston M. McCourt, Dawn A. Lowe, Dana M Talsness, Christopher M. Chamberlain, John T. Olthoff, D'anna M. Nelson
Publikováno v:
Human molecular genetics. 25(22)
Absence of the protein dystrophin causes Duchenne muscular dystrophy. Dystrophin directly binds to microtubules in vitro, and its absence in vivo correlates with disorganization of the subsarcolemmal microtubule lattice, increased detyrosination of
Autor:
Joseph M. Muretta, David D. Thomas, John A. Rohde, Tara L. Mader, Lien A. Phung, Dawn A. Lowe, Karl J. Petersen
Publikováno v:
Biophysical Journal. 112:237a
Muscle myosins use the energy from ATP hydrolysis to perform mechanical work during muscle contraction. Recent work suggests that the interactions between the catalytic and light-chain-binding domains of myosin, the S2 coiled-coil fragment, and the t