Výsledky vyhledávání - "Tara L Houchen"

Pharmacokinetics and Metabolism of the Prodrug DB289 (2,5-Bis[4-(N-methoxyamidino)phenyl]furan Monomaleate) in Rat and Monkey and Its Conversion to the Antiprotozoal/Antifungal Drug DB75 (2,5-Bis(4-guanylphenyl)furan Dihydrochloride)

Autor: Karen Fitzpatrick, Ian Midgley, Lynne M. Taylor, Zbigniew R. Cybulski, David W. Boykin, Simon J. Henderson, A. McBurney, B. A. John, Kerri L. Trendler, Tara L. Houchen, Sarah J. Wright

Publikováno v: Drug Metabolism and Disposition. 35:955-967

DB289 (pafuramidine maleate; 2,5-bis[4-(N-methoxyamidino)phenyl]furan monomaleate) is a prodrug of DB75 (furamidine dihydrochloride; 2,5-bis(4-guanylphenyl)furan dihydrochloride), an aromatic dication related to pentamidine that has demonstrated good

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4a389938d19eb0c59678c7a106a83a
https://doi.org/10.1124/dmd.106.013391

Zobrazit plný text záznamu

Intramuscular injection of 125I-botulinum neurotoxin-complex versus 125I-botulinum-free neurotoxin: time course of tissue distribution

Autor: Leslie F Chasseaud, Diane D.-S. Tang-Liu, J. Oliver Dolly, Colin Webber, Tara L Houchen, K. Roger Aoki, Anton de Paiva

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 42(5)

The diffusion from the site of intramuscular injection of 900 kDa botulinum neurotoxin-hemagglutinin complex (BoNT/A-complex) and 150 kDa free-botulinum neurotoxin (free-BoNT/A) was compared. Radioiodinated compounds were injected into the gastrocnem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0deba92a763e55fef074edb420d2eb1
https://pubmed.ncbi.nlm.nih.gov/14529727

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání