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Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 73:1005-1011
Sitamaquine (WR6026) is an 8-aminoquinoline in development for the oral treatment of visceral leishmaniasis (VL). This was an open-label, dose-increasing study to determine the dose-response and safety profile for sitamaquine in Kenyan patients with
Autor:
Tara K, Jha, Shyam, Sundar, Chandreshwar P, Thakur, J Mark, Felton, Antony J, Sabin, John, Horton
Publikováno v:
The American journal of tropical medicine and hygiene. 73(6)
This randomized, open label, multicenter study assessed the dose-response and safety profile for oral sitamaquine in 120 Indian subjects with visceral leishmaniasis (VL). Patients aged 5-64 years (mean age 21.2 years) received one of four sitamaquine