Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tara Capece"'
Autor:
Yeonsun Hong, Hye-Ran Kim, Brandon L. Walling, John Lozada, Andrea M. Amitrano, Cooper J. Sailer, Kihong Lim, Raj Kumar Mongre, Kyun-Do Kim, Tara Capece, Elena B. Lomakina, Nicholas S. Reilly, Richard E. Waugh, Patrick M. Reagan, Minsoo Kim, Patrick W. Oakes, Chang-Duk Jun
Publikováno v:
Journal of Clinical and Translational Science, Vol 6, Pp 57-57 (2022)
OBJECTIVES/GOALS: #NAME? METHODS/STUDY POPULATION: Cell culture & protein identification: human T cells were purified from healthy blood, then activated & cultured for 5d. CAR-T cells were collected from infusion bags of cancer patients undergoing CA
Externí odkaz:
https://doaj.org/article/f605ef69391e4c20b5889316e4a19c02
Autor:
Kyun-Do Kim, Seyeon Bae, Tara Capece, Hristina Nedelkovska, Rafael G. de Rubio, Alan V. Smrcka, Chang-Duk Jun, Woojin Jung, Byeonghak Park, Tae-il Kim, Minsoo Kim
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Regulatory T cells (Tregs) promote immune suppression in the tumour. Here, the authors show that Tregs suppress cytotoxic T lymphocyte (CTL) activity by impairing Ca2+ signalling and that adoptive transfer of CTLs engineered with an optogenetic contr
Externí odkaz:
https://doaj.org/article/eaff6961123b44e39ab2cbba3d2edb63
Autor:
Sara A Knowlden, Tara Capece, Milan Popovic, Timothy J Chapman, Fariba Rezaee, Minsoo Kim, Steve N Georas
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101655 (2014)
Lysophosphatidic acid (LPA) and the LPA-generating enzyme autotaxin (ATX) have been implicated in lymphocyte trafficking and the regulation of lymphocyte entry into lymph nodes. High local concentrations of LPA are thought to be present in lymph node
Externí odkaz:
https://doaj.org/article/6593f6d438a54d77b3488c7aab307c3e
Autor:
Yeonsun Hong, Brandon L. Walling, Hye-Ran Kim, William S. Serratelli, John R. Lozada, Cooper J. Sailer, Andrea M. Amitrano, Kihong Lim, Raj Kumar Mongre, Kyun-Do Kim, Tara Capece, Elena B. Lomakina, Nicholas S. Reilly, Kevin Vo, Scott A. Gerber, Tan-Chi Fan, Alice Lin-Tsing Yu, Patrick W. Oakes, Richard E. Waugh, Chang-Duk Jun, Patrick M. Reagan, Minsoo Kim
Publikováno v:
Nature Immunology. 24:1007-1019
Autor:
Tara Capece, David J. Topham, Kyun-Do Kim, Kihong Lim, Seyeon Bae, Brandon L. Walling, Henry H. Chung, Minsoo Kim
Publikováno v:
The Journal of Cell Biology
LFA-1 mediates T cell migration and their stable interaction with antigen-presenting cells, but how intracellular LFA-1 dynamically and spatially regulates T cell function is unclear. Capece et al. now demonstrate that intracellular LFA-1 in naive CD
Autor:
Byeonghak Park, Minsoo Kim, Woojin Jung, Alan V. Smrcka, Tae Il Kim, Rafael Gil de Rubio, Tara Capece, Chang-Duk Jun, Kyun Do Kim, Hristina Nedelkovska, Seyeon Bae
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications
Adoptive cell transfer utilizing tumour-targeting cytotoxic T lymphocytes (CTLs) is one of the most effective immunotherapies against haematological malignancies, but significant clinical success has not yet been achieved in solid tumours due in part
Autor:
Minsoo Kim, Tara Capece
Publikováno v:
Molecules and Cells
Long-term immunity to many viral and bacterial pathogens requires CD8(+) memory T cell development, and the induction of long-lasting CD8(+) memory T cells from a naïve, undifferentiated state is a major goal of vaccine design. Formation of the memo
Autor:
Justin Schumacher, Angela Hughson, Ninoshka R. J. Fernandes, Hannah S. Bell, James H. Miller, Alan V. Smrcka, Christopher S. Anderson, Hen Prizant, Deborah J. Fowell, Brandon L. Walling, Alison Gaylo-Moynihan, Milan Popovic, Minsoo Kim, Kevin Chiou, David J. Topham, Tara Capece, Dillon C. Schrock
Publikováno v:
Immunity
T-helper (Th) cell differentiation drives specialized gene programs that dictate effector T cell function at sites of infection. Here we have shown Th cell differentiation also imposes discrete motility gene programs that shape Th1 and Th2 cell navig
Autor:
Tara Capece, Young-Min Hyun, Minsoo Kim, Kris Lambert-Emo, Seyeon Bae, Richard J. Miller, Kihong Lim, David J. Topham
Publikováno v:
Science (New York, N.Y.). 349(6252)
Neutrophils lay down the tracks T cells constantly circulate throughout the body until an invading pathogen calls them into action. Microbes often cause localized infections, so how do T cells know where to go? Lim et al. explore this question in a m
Autor:
Kyun Do Kim, Seyeon Bae, Tara Capece, Hristina Nedelkovska, Rafael G de Rubio, Alan V Smrcka, Woojin Jung, Byeonghak Park, Tae-il Kim, Sonal Srikanth, Yousang Gwack, Minsoo Kim
Publikováno v:
The Journal of Immunology. 198:126.3-126.3
Adoptive cell transfer utilizing tumor-targeting cytotoxic T lymphocytes (CTLs) is one of the most effective immunotherapies against hematological malignancies, but significant clinical success has not yet been achieved in solid tumors due in part to