Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Tara C. White"'
Identification and characterization of novel mutations implicated in congenital fibrinogen disorders
Autor:
Courtney D. Thornburg, Natalie Smith, Salvador Minoldo, Tara C. White-Adams, Jorge Di Paola, Larissa Bornikova, Donald S. Backos, Hugo A. Guglielmone, Leila Noetzli, Alisa S. Wolberg, Linda J. Jacobson, Marilyn J. Manco-Johnson, Miguel A. Escobar
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Research and practice in thrombosis and haemostasis, vol 2, iss 4
Research and practice in thrombosis and haemostasis, vol 2, iss 4
Essentials Fibrinogen Disorders are characterized by variable expressivity.Patients with fibrinogen disorders can present with bleeding, thrombosis, or both.As previously reported, genotype‐phenotype correlations are difficult to establish.Molecula
Autor:
José A. López, Keith R. McCrae, Dominic W. Chung, Marilyn J. Manco-Johnson, Venkaiah Betapudi, Christopher J. Ng, Katrina J. Ashworth, Jing-fei Dong, Lucas J. Sosa, Alice Liu, Tara C. White-Adams, Jorge Di Paola
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Essentials The antiphospholipid syndrome predisposes to thrombosis due to activation of endothelium and blood components.The role of anti‐β2GPI antibodies in VWF release and ADAMTS13 function is not well understood.Some anti‐β2GPI antibodies in
Autor:
Hugo A. Guglielmone, Salvador Minoldo, Natalie Smith, J. Di Paola, Tara C. White-Adams, G. Jarchum
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 22(5)
Autor:
Christopher J. Ng, Tara C. White-Adams, Jorge Di Paola, Paula M. Jacobi, Sandra L. Haberichter
Publikováno v:
Thrombosis research. 145
Type 1 von Willebrand disease (VWD) is characterized by low plasma levels of von Willebrand factor (VWF) and clinical bleeding. Several mechanisms have been described that cause a decrease in plasma VWF levels in VWD, and the goal of this study was t
Autor:
Owen J. T. McCarty, Michelle A. Berny, Tara C. White-Adams, Andras Gruber, Ishan Patel, David Gailani, Erik I. Tucker
Publikováno v:
Journal of Thrombosis and Haemostasis. 8:1295-1301
Summary. Background: Laminin is the most abundant non-collagenous protein in the basement membrane. Recent studies have shown that laminin supports platelet adhesion, activation and aggregation under flow conditions, highlighting a possible role for
Autor:
Jacqueline M. Gertz, Andras Gruber, Michelle A. Berny, Erik I. Tucker, Philip G. de Groot, Owen J. T. McCarty, Tara C. White-Adams, David Gailani, Rolf T. Urbanus
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 29:1602-1607
Objective— Factor XI (FXI) promotes hemostasis and thrombosis through enhancement of thrombin generation and has been shown to play a critical role in the formation of occlusive thrombi in arterial injury models. The aim of this study was to invest
Autor:
Sari A. Jouihan, Antony C. Bakke, Rehana S. Lovely, Chantelle M. Rein, Lynn K. Boshkov, David H. Farrell, Tara C. White, Owen J. T. McCarty
Publikováno v:
Thrombosis and Haemostasis. 100:837-846
The minor gammaA/gamma' fibrinogen isoform contains a high affinity binding site for thrombin exosite II that is lacking in the major gammaA/gammaA fibrinogen isoform. We therefore investigated the biological consequences of the gamma' chain binding
Autor:
Patrick Simonson, Sandra Rugonyi, Ishan Patel, Andras Gruber, Tara C. White-Adams, Owen J. T. McCarty, Michelle A. Berny
Publikováno v:
Cellular and Molecular Bioengineering. 3:187-189
The underlying pathogenesis of cardiovascular disease is the formation of occlusive thrombi. While many well-defined animal models recapitulate the process of intravascular thrombosis, there is a need for validated ex vivo models of occlusive thrombu
Publikováno v:
Langmuir
[Image: see text] Von Willebrand factor (VWF) binding and platelet adhesion to subendothelial collagens are initial events in thrombus formation at sites of vascular injury. These events are often studied in vitro using flow assays designed to mimic
Autor:
David Gailani, Qiufang Cheng, Mao Fu Sun, Owen J. T. McCarty, India Sisler, Stephanie A. Smith, Anton Matafonov, Erik I. Tucker, Tara C. White-Adams, Thomas Renné, Andras Gruber, Meghann S. Pine, Stephen R. Hanson
Publikováno v:
Blood. 116(19)
Mice lacking factor XII (fXII) or factor XI (fXI) are resistant to experimentally–induced thrombosis, suggesting fXIIa activation of fXI contributes to thrombus formation in vivo. It is not clear whether this reaction has relevance for thrombosis i