Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tara Al-Barazenji"'
Autor:
Hoda Gad, Idris Mohammed, Hajar Dauleh, Maheen Pasha, Tara Al-Barazenji, Khalid Hussain, Rayaz A. Malik
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Melanocortin 4 receptor (MC4R) mutations are the commonest cause of monogenic obesity through dysregulation of neuronal pathways in the hypothalamus and prefrontal cortex that regulate hunger and satiety. MC4R also regulates neuropathic pain pathways
Externí odkaz:
https://doaj.org/article/69943c9323e14e789399a727c672d5c5
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
IntroductionPremature ovarian insufficiency (POI) is a primary cause of infertility with variable clinical manifestations. POI is a multifactorial disease with both environmental and known genetic etiologies, but data on the genetic variations associ
Externí odkaz:
https://doaj.org/article/3fc01cacd45a44908a2082ff81f2b295
Autor:
Lubna I. Abu-Rub, Tara Al-Barazenji, Sumaya Abiib, Ayat S Hammad, Alaa Abbas, Khalid Hussain, Mashael Al-Shafai
Publikováno v:
Genes, Vol 15, Iss 8, p 966 (2024)
The kinase suppressor of Ras 2 (KSR2) gene is associated with monogenic obesity, and loss-of-function variants in KSR2 have been identified in individuals with severe early-onset obesity. This study investigated KSR2 variants in 9 pediatric patients
Externí odkaz:
https://doaj.org/article/4add91af706a4f07816f2c236f01ba7c
Autor:
Arij Fouzat Hassan, Ola Hussein, Tara Al-Barazenji, Asma Allouch, Layla Kamareddine, Ahmed Malki, Ala‐Eddin Al Moustafa, Ashraf Khalil
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27002- (2024)
In colorectal cancer (CRC), aberrations in KRAS are associated with aggressive tumorigenesis and an overall low survival rate because of chemoresistance and adverse effects. Ergo, complementary, and integrative medicines are being considered for CRC
Externí odkaz:
https://doaj.org/article/28f102d7e56348c99c7613a5633a6a5e
Autor:
Idris Mohammed, Senthil Selvaraj, Wesam S. Ahmed, Tara Al-Barazenji, Ayat S Hammad, Hajar Dauleh, Luis R. Saraiva, Mashael Al-Shafai, Khalid Hussain
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16361 (2023)
The leptin–melanocortin pathway is pivotal in appetite and energy homeostasis. Pathogenic variants in genes involved in this pathway lead to severe early-onset monogenic obesity (MO). The MC4R gene plays a central role in leptin–melanocortin sign
Externí odkaz:
https://doaj.org/article/cfec28209f40430798c9a49b91d9db91