Impairment of the neurotrophic signaling hub B-Raf contributes to motoneuron degeneration in spinal muscular atrophy

Autor: Hensel, Niko, Cieri, Federica, Santonicola, Pamela, Tapken, Ines, Schüning, Tobias, Taiana, Michela, Pagliari, Elisa, Joseph, Antonia, Fischer, Silke, Heidrich, Natascha, Brinkmann, Hella, Kubinski, Sabrina, Bergmann, Anke K., Richter, Manuela F., Jung, Klaus, Corti, Stefania, Di Schiavi, Elia, Claus, Peter

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2021 May 01. 118(18), 1-11.

Externí odkaz: https://www.jstor.org/stable/27040364

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The systemic complexity of a monogenic disease: the molecular network of spinal muscular atrophy.

Autor: Tapken I; SMATHERIA gGmbH - Non-Profit Biomedical Research Institute, 30625 Hannover, Germany.; Center for Systems Neurosciences (ZSN), 30559 Hannover, Germany., Schweitzer T; Research Core Unit Proteomics, Hannover Medical School (MHH), 30625 Hannover, Germany.; Institute of Toxicology, Hannover Medical School (MHH), 30625 Hannover, Germany., Paganin M; Institute of Biophysics, CNR Unit, 38123 Trento, Italy., Schüning T; SMATHERIA gGmbH - Non-Profit Biomedical Research Institute, 30625 Hannover, Germany., Detering NT; SMATHERIA gGmbH - Non-Profit Biomedical Research Institute, 30625 Hannover, Germany.; Center for Systems Neurosciences (ZSN), 30559 Hannover, Germany., Sharma G; Institute of Biophysics, CNR Unit, 38123 Trento, Italy., Niesert M; Heidelberg University, Center for Pediatrics and Adolescent Medicine, Department of Pediatrics I, 69120 Heidelberg, Germany., Saffari A; Heidelberg University, Center for Pediatrics and Adolescent Medicine, Department of Pediatrics I, 69120 Heidelberg, Germany., Kuhn D; SMATHERIA gGmbH - Non-Profit Biomedical Research Institute, 30625 Hannover, Germany.; Department of Conservative Dentistry, Periodontology and Preventive Dentistry, Hannover Medical School, 30625 Hannover, Germany., Glynn A; SMATHERIA gGmbH - Non-Profit Biomedical Research Institute, 30625 Hannover, Germany., Cieri F; Institute of Biosciences and Bioresources (IBBR), CNR, 80131 Naples, Italy.; Department of Biology, University of Naples Federico II, 80131 Naples, Italy., Santonicola P; Institute of Biosciences and Bioresources (IBBR), CNR, 80131 Naples, Italy., Cannet C; Bruker Biospin GmbH, 76275 Ettlingen, Germany., Gerstner F; Carl-Ludwig-Institute for Physiology, Leipzig University, 04103 Leipzig, Germany., Faller KME; Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, EH8 9AG Edinburgh, UK., Huang YT; Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, EH8 9AG Edinburgh, UK., Kothary R; Ottawa Hospital Research Institute, Ottawa, Canada and Faculty of Medicine, University of Ottawa, K1H 8L6 Ottawa, Canada., Gillingwater TH; Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, EH8 9AG Edinburgh, UK., Di Schiavi E; Institute of Biosciences and Bioresources (IBBR), CNR, 80131 Naples, Italy., Simon CM; Carl-Ludwig-Institute for Physiology, Leipzig University, 04103 Leipzig, Germany., Hensel N; Department of Anatomy and Cell Biology, Martin Luther University Halle-Wittenberg, Faculty of Medicine, 06108 Halle (Saale), Germany., Ziegler A; Heidelberg University, Center for Pediatrics and Adolescent Medicine, Department of Pediatrics I, 69120 Heidelberg, Germany., Viero G; Institute of Biophysics, CNR Unit, 38123 Trento, Italy., Pich A; Research Core Unit Proteomics, Hannover Medical School (MHH), 30625 Hannover, Germany.; Institute of Toxicology, Hannover Medical School (MHH), 30625 Hannover, Germany., Claus P; SMATHERIA gGmbH - Non-Profit Biomedical Research Institute, 30625 Hannover, Germany.; Center for Systems Neurosciences (ZSN), 30559 Hannover, Germany.

Publikováno v: Brain : a journal of neurology [Brain] 2024 Aug 26. Date of Electronic Publication: 2024 Aug 26.