Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tapio Haavisto"'
Publikováno v:
Aquatic Toxicology. 86:388-396
Two wood extractives, dehydroabietic acid (DHAA) and betulinol (BET), present in wood industry effluents were evaluated for their potential effects on the reproductive physiology of zebrafish. Adult zebrafish (F0) were exposed in a continuous flow-th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be1fca5a267ab820611ae9ee546830f
https://doi.org/10.1016/j.aquatox.2007.12.001
https://doi.org/10.1016/j.aquatox.2007.12.001
In Utero and Lactational Exposure to TCDD; Steroidogenic Outcomes Differ in Male and Female Rat Pups
Autor:
Tapio Haavisto, Leon J. S. Brokken, S. A. Myllymäki, Matti Viluksela, Jorma Paranko, Jorma Toppari
Publikováno v:
Toxicological Sciences. 88:534-544
TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) has a potency to induce decreased fertility and structural reproductive anomalies in male and female mammals. While the activity profile of sex steroid hormone production distinctly differs in developing mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652a8e02a14cd0e78963a16aab60b45d
https://doi.org/10.1093/toxsci/kfi308
https://doi.org/10.1093/toxsci/kfi308
Publikováno v:
Toxicology and Applied Pharmacology. 204:69-80
Isolated rat ovarian follicles grow and produce steroid hormones in vitro and so provide a good model for studying the effects of hormonally active compounds on follicular steroidogenesis. We have evaluated the effects of diethylstilbestrol (DES), ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9342626baac7c4995a32502b464e7691
https://doi.org/10.1016/j.taap.2004.08.009
https://doi.org/10.1016/j.taap.2004.08.009
Publikováno v:
Reproductive Toxicology. 17:593-605
In the present study, we evaluated the effects that 4-tert-octylphenol (OP) and 4-tert-butylphenol (BP) had on the prenatal testicular testosterone surge at embryonic day (ED) 19.5 in the rat. In utero exposure to alkylphenols (0.1-100 mg/kg maternal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77be8d05cf883785d2dd0a3372173d54
https://doi.org/10.1016/s0890-6238(03)00103-5
https://doi.org/10.1016/s0890-6238(03)00103-5
Publikováno v:
Bioconjugate Chemistry. 9:725-735
We describe the site-specific enzymatic biotinylation of recombinant anti-estradiol Fab fragments through a 13 amino acid acceptor peptide translationally fused to the C-terminus of the Fd chain. The Fab-peptide fusion proteins were secreted to the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f158df2f0afa89c07ac780e18bf7a214
https://doi.org/10.1021/bc9800217
https://doi.org/10.1021/bc9800217
Autor:
Matti Viluksela, Jorma Paranko, N. A. Adamsson, Tapio Haavisto, S. A. Myllymäki, Leon J. S. Brokken, Jorma Toppari
Publikováno v:
International journal of andrology. 29(2)
Exposure of adult male animals to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) decreases serum androgen concentrations. Reduction in androgen levels after maternal exposure has also been reported, but these results have not been reproduced. We have ear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3f98a00191740ef1f4023c58dc8bce
https://pubmed.ncbi.nlm.nih.gov/16533353
https://pubmed.ncbi.nlm.nih.gov/16533353
Publikováno v:
Toxicology and applied pharmacology. 207(1)
Phenolic compounds, such as 4-tert-octylphenol (OP), have been shown to interfere with rat ovarian steroidogenesis. However, little is known about steroidogenic effects of infantile OP exposure on immature ovary. The aim of the present study was to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9393d2bf54568bfb8dae63600d3eb497
https://pubmed.ncbi.nlm.nih.gov/16054900
https://pubmed.ncbi.nlm.nih.gov/16054900
Autor:
Jouni T. Tuomisto, Richard E. Peterson, Ulla Simanainen, Matti Viluksela, Jorma Toppari, Tapio Haavisto, Jouko Tuomisto, Jorma Paranko
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 80(1)
Male reproductive effects induced by in utero and lactational exposure to TCDD were analyzed in three rat lines that are differently sensitive to TCDD. Rats from lines A, B, and C were selectively bred from TCDD-resistant Han/Wistar (Kuopio, H/W) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5b2b748507a473e9a79ce01d1d2868
https://pubmed.ncbi.nlm.nih.gov/15084753
https://pubmed.ncbi.nlm.nih.gov/15084753
Autor:
Hannele Huuskonen, Tapio Haavisto, Jorma Paranko, Raimo Pohjanvirta, Faraj El-Gehani, Katri Nurmela
Publikováno v:
University of Helsinki
Changes in the perinatal testosterone surge have been related to demasculinization of the central nervous system and androgen-dependent growth of the reproductive organs in male mammals. Earlier reports suggest that 2,3,7,8-tetrachlorodibenzo-p-dioxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94263c92f4c6dd4ed266a0ea284d371d
https://pubmed.ncbi.nlm.nih.gov/11403907
https://pubmed.ncbi.nlm.nih.gov/11403907