Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Tapas K. Pradhan"'
Autor:
Terry W. Moody, Nieves González, Tapas K. Pradhan, Samuel A. Mantey, Robert T. Jensen, David H. Coy, Veronica Sancho
Publikováno v:
Peptides. 30:1473-1486
The mammalian Bombesin (Bn) peptides neuromedin B (NMB) and gastrin-releasing peptide (GRP) actions are mediated by two receptors (NMB-receptor, GRP-receptor) which are widely distributed in the GI tract and CNS. From primarily animal studies NMB/GRP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5663279502bb37f2a2030ffdbce88a97
https://doi.org/10.1016/j.peptides.2009.05.007
https://doi.org/10.1016/j.peptides.2009.05.007
Autor:
Lin Shen, Tapas K. Pradhan, Nieves González, Michael Schumann, Robert T. Jensen, David H. Coy, Samuel A. Mantey
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 319:980-989
Mammalian bombesin (Bn) receptors include the gastrin-releasing peptide receptor, neuromedin B receptor, and bombesin receptor subtype 3 (BRS-3). These receptors are involved in a variety of physiological/pathologic processes, including thermoregulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a6bf8565c50fcfe3a6c7d7c8b85053
https://doi.org/10.1124/jpet.106.107011
https://doi.org/10.1124/jpet.106.107011
Autor:
Tapas K. Pradhan1, Wayne E. Criss1
Publikováno v:
European Journal of Biochemistry. Apr74 Part 2, Vol. 43 Issue 3, p541-547. 7p.
Autor:
Tapas K. Pradhan, Joseph A. Fuselier, Robert T. Jensen, Samuel A. Mantey, David H. Coy, Terry W. Moody, Tomoo Nakagawa
Publikováno v:
Peptides. 26:1560-1566
The effects of camptothecin-somatostatin (CPT-SS) conjugates were investigated on small cell lung cancer (SCLC) cells. CPT was coupled to a SS agonist (SSA), c(Cys-Phe-DTrp-Lys-Thr-Cys)Thr-NH2 using the built in nucleophile assisted-releasing group (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6108b173461683bc6d736a99bae568a4
https://doi.org/10.1016/j.peptides.2005.02.025
https://doi.org/10.1016/j.peptides.2005.02.025
Autor:
Tapas K. Pradhan, Hisato Igarashi, David H. Coy, Tetsuhide Ito, Wei Hou, Robert T. Jensen, Samuel A. Mantey
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 315:370-381
Vasoactive intestinal peptide (VIP) is a widespread neurotransmitter whose physiological and pathophysiological actions are mediated by two receptor classes, VIP/pituitary adenylate cyclase-activating polypeptide (VPAC) 1 and VPAC2. VIP is a 28-amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd11b837158d6c1a22d8054573c859f
https://doi.org/10.1124/jpet.105.088823
https://doi.org/10.1124/jpet.105.088823
Autor:
Michael Schumann, David H. Coy, Tapas K. Pradhan, Samuel A. Mantey, Terry W. Moody, Alfredo Martínez, Robert T. Jensen, Tomoo Nakagawa, Joseph A. Fuselier
Publikováno v:
Journal of Biological Chemistry. 279:23580-23589
Mammalian bombesin (BN) receptors are among those most frequently overexpressed by a number of common tumors including prostate, breast, lung, and colon cancers. The aim of this study was to develop a camptothecin-bombesin (CPT-BN) conjugate that int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a4b9939fd85c47f3aab69e5c0eaab0
https://doi.org/10.1074/jbc.m401938200
https://doi.org/10.1074/jbc.m401938200
Autor:
Robert T. Jensen, Tetsuhide Ito, David H. Coy, Simon J. Hocart, Charles D. Ulrich, Samuel A. Mantey, Tapas K. Pradhan, Hisato Igarashi, Wei Hou
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 301:37-50
Vasoactive intestinal peptide (VIP) is a neurotransmitter involved in a number of pathological and physiological processes. VIP is rapidly degraded and simplified stable analogs are needed. VIP's action was extensively studied in rat and guinea pig.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde2b19c3d27e7e8f60d4927fcb920f8
https://doi.org/10.1124/jpet.301.1.37
https://doi.org/10.1124/jpet.301.1.37
Autor:
Robert T. Jensen, Tetsuhide Ito, David H. Coy, John E. Taylor, William A. Murphy, Hisato Igarashi, Samuel A. Mantey, Tapas K. Pradhan, Wei Hou
Publikováno v:
Peptides. 22:1139-1151
Growth hormone (GH) is used or is being evaluated for efficacy in treatment of short stature, aspects of aging, cardiac disorders, Crohn's disease, and short bowel syndrome. Therefore, we synthesized several stable growth hormone-releasing factor (GR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf828f2c033a4d9e059d18c37c34d49
https://doi.org/10.1016/s0196-9781(01)00436-3
https://doi.org/10.1016/s0196-9781(01)00436-3
Autor:
Tapas K. Pradhan, Tatsuro Katsuno, D. H. Coy, Mark A. Akeson, R.R. Ryan, Wei Hou, James F. Battey, Patrick J. Donohue, Eliot R. Spindel, Robert T. Jensen, Samuel A. Mantey
Publikováno v:
Biochemistry. 38:7307-7320
Recently, a fourth member of the bombesin (Bn) receptor family (fBB4-R) was isolated from a cDNA library from the brain of the frog, Bombina orientalis. Its pharmacology and cell biology are largely unknown, and no known natural cell lines or tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ce084eeb72aeb290c620a4ff3587c2
https://doi.org/10.1021/bi990204w
https://doi.org/10.1021/bi990204w
Autor:
Eduardo Sainz, R.R. Ryan, Robert T. Jensen, Tapas K. Pradhan, James F. Battey, H. Christian Weber, Samuel A. Mantey, David H. Coy, Mark A. Akeson, Eliot R. Spindel, Robert P. Searles
Publikováno v:
Journal of Biological Chemistry. 272:26062-26071
An orphan receptor discovered in 1993 was called bombesin receptor subtype 3 (BRS-3) because of 47-51% amino acid identity with bombesin (Bn) receptors. Its pharmacology is unknown, because no naturally occurring tissues have sufficient receptors to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b8ad42e57923de9b808145d0604a68
https://doi.org/10.1074/jbc.272.41.26062
https://doi.org/10.1074/jbc.272.41.26062