Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Tapas K, Das Gupta"'
Autor:
Juliana K. Choi, Samer A. Naffouje, Masahide Goto, Jing Wang, Konstantin Christov, David J. Rademacher, Albert Green, Arlene A. Stecenko, Ananda M. Chakrabarty, Tapas K. Das Gupta, Tohru Yamada
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
A bidirectional interaction between Pseudomonas aeruginosa (PA) bacteria and cancerous tumors results in an anti-tumor effect; cancer cells stimulate PA-secretion of azurin which promotes tumor cell production of aldolase A.
Externí odkaz:
https://doaj.org/article/c00b7dc40e6f42159592b3df8c06fd59
Autor:
Sunam Mander, Samer A. Naffouje, Jin Gao, Weiguo Li, Konstantin Christov, Albert Green, Ernesto R. Bongarzone, Tapas K. Das Gupta, Tohru Yamada
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Despite recent advances in cancer research, glioblastoma multiforme (GBM) remains a highly aggressive brain tumor as its treatment options are limited. The current standard treatment includes surgery followed by radiotherapy and adjuvant chemotherapy
Externí odkaz:
https://doaj.org/article/c8c5606c174b491ca4ad1ddca4b6f72f
Autor:
Masahide Goto, Ingeun Ryoo, Samer Naffouje, Sunam Mander, Konstantin Christov, Jing Wang, Albert Green, Anne Shilkaitis, Tapas K. Das Gupta, Tohru Yamada
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103850- (2022)
Summary: Background: Given the lack of visual discrepancy between malignant and surrounding normal tissue, current breast conserving surgery (BCS) is associated with a high re-excision rate. Due to the increasing cases of BCS, a novel method of compl
Externí odkaz:
https://doaj.org/article/f4daa1d6aa3448d8a9e2e7591f0165bb
Western Analysis and Pull-down assay data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3a92d3acb4091d25e5b2c8b7f54f93
https://doi.org/10.1158/0008-5472.22409760
https://doi.org/10.1158/0008-5472.22409760
p28 is an anionic cell-penetrating peptide of 28 amino acids that activates wild-type and mutated p53, leading subsequently to selective inhibition of CDK2 and cyclin A expression and G2–M cell-cycle arrest. In this study, we investigated the cytot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83498943209a52545460044c66c9ac0c
https://doi.org/10.1158/0008-5472.c.6507852.v1
https://doi.org/10.1158/0008-5472.c.6507852.v1
Autor:
Samer A. Naffouje, Masahide Goto, Lori U. Coward, Gregory S. Gorman, Konstantin Christov, Jing Wang, Albert Green, Anne Shilkaitis, Tapas K. Das Gupta, Tohru Yamada
Publikováno v:
Journal of Medicinal Chemistry. 65:7371-7379
Precise identification of the tumor margins during breast-conserving surgery (BCS) remains a challenge given the lack of visual discrepancy between malignant and surrounding normal tissues. Therefore, we developed a fluorescent imaging agent, ICG-p28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c8aca0b6f0e72f548654fa999d207f
https://doi.org/10.1021/acs.jmedchem.2c00417
https://doi.org/10.1021/acs.jmedchem.2c00417
Autor:
Sunam Mander, Gregory S Gorman, Lori U Coward, Konstantin Christov, Albert Green, Tapas K Das Gupta, Tohru Yamada
Publikováno v:
Neuro-Oncology Advances. 5
Background Brain metastases (BMs), the most common tumors of the central nervous system, are life-threatening with a dismal prognosis. The major challenges to developing effective treatments for BMs are the limited abilities of drugs to target tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf4d2e4b2097b04af4356e3e57079dd6
https://doi.org/10.1093/noajnl/vdad042
https://doi.org/10.1093/noajnl/vdad042
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071618103
Methods in Molecular Biology ISBN: 9781071618103
Precise surgical resection directly influences the prognosis and survival of patients with solid tumors. However, it is often difficult to distinguish tumor from normal tissue during resection without any intraoperative imaging guidance. Image-guided
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e3f227fee3d5806db976ce094e6111
https://pubmed.ncbi.nlm.nih.gov/35094362
https://pubmed.ncbi.nlm.nih.gov/35094362
Autor:
Juliana K, Choi, Samer A, Naffouje, Masahide, Goto, Jing, Wang, Konstantin, Christov, David J, Rademacher, Albert, Green, Arlene A, Stecenko, Ananda M, Chakrabarty, Tapas K, Das Gupta, Tohru, Yamada
Publikováno v:
Communications biology. 6(1)
Microorganisms living at many sites in the human body compose a complex and dynamic community. Accumulating evidence suggests a significant role for microorganisms in cancer, and therapies that incorporate bacteria have been tried in various types of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81b2ae4c40773c9dbfedd80517c3743f
https://pubmed.ncbi.nlm.nih.gov/36609683
https://pubmed.ncbi.nlm.nih.gov/36609683
Autor:
Andrea Turner, Liang-Cheng Li, Tania Pilli, Lixia Qian, Elizabeth Louise Wiley, Suman Setty, Konstantin Christov, Lakshmy Ganesh, Ajay V Maker, Peifeng Li, Prasad Kanteti, Tapas K Das Gupta, Bellur S Prabhakar
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56817 (2013)
The Map kinase Activating Death Domain containing protein (MADD) isoform of the IG20 gene is over-expressed in different types of cancer tissues and cell lines and it functions as a negative regulator of apoptosis. Therefore, we speculated that MADD
Externí odkaz:
https://doaj.org/article/53082f3be0654141b04398df0364129a