Zobrazeno 1 - 10 of 64 pro vyhledávání: '"Tapani K"'
1
Akademický článek
MANF Is Neuroprotective in Early Stages of EAE, and Elevated in Spinal White Matter by Treatment With Dexamethasone
Autor: Jinhan Nam, Tapani K. Koppinen, Merja H. Voutilainen
Publikováno v: Frontiers in Cellular Neuroscience, Vol 15 (2021)
Multiple sclerosis (MS) is a progressive autoimmune disease characterized by T-cell mediated demyelination in central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is a widely used in vivo disease model of MS. Glucocorticoids
Externí odkaz: https://doaj.org/article/2f346f82558d4a35bdb2ce12542147d3
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2
Akademický článek
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3
Akademický článek
The Catechol O-Methyltransferase Inhibitor Entacapone in the Treatment of Parkinson’s Disease: Personal Reflections on a First-in-Class Drug Development Programme 40 Years On
Autor: Pekka T. Männistö, Tapani Keränen, Kari J. Reinikainen, Anna Hanttu, Piero Pollesello
Publikováno v: Neurology and Therapy, Vol 13, Iss 4, Pp 1039-1054 (2024)
Abstract In the 1980s, Orion Pharma, then a mid-ranking Nordic area pharmaceutical company, established a drug development programme on the inhibition of catechol O-methyltransferase (COMT). This enzyme, which plays an important role in the inactivat
Externí odkaz: https://doaj.org/article/ab03be095a6f4a37aad0b8a4273760c0
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4
MANF Is Neuroprotective in Early Stages of EAE, and Elevated in Spinal White Matter by Treatment With Dexamethasone
Autor: Nam, Jinhan, Koppinen, Tapani K., Voutilainen, Merja H.
Publikováno v: Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Multiple sclerosis (MS) is a progressive autoimmune disease characterized by T-cell mediated demyelination in central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is a widely used in vivo disease model of MS. Glucocorticoids
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::73796c7f0ba54bd571fc23023157bde6
http://europepmc.org/articles/PMC8292680
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5
Akademický článek
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7
Development and plasticity of meningeal lymphatic vessels
Autor: Mart Saarma, Aleksanteri Aspelund, Salli Antila, Sinem Karaman, Dmitri Chilov, Jean-Leon Thomas, Zhilin Li, Shentong Fang, Harri Nurmi, Merja H. Voutilainen, Kari Alitalo, Tapani K. Koppinen, Thomas Mathivet, Anne Eichmann, Jun-Hee Park, Mikko Airavaara
Publikováno v: The Journal of Experimental Medicine
Antila et al. show that meningeal lymphatic vessels in mice develop postnatally. Interruption of VEGF-C/VEGFR3 signal transduction arrests their development. In adult mice, VEGFR3 deletion and VEGFR3 blockers, including a clinically available tyrosin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b595f385840157d68ec9fa2f02f841b
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8
Akademický článek
Feasibility and patient acceptability of a commercially available wearable and a smart phone application in identification of motor states in parkinson's disease.
Autor: Sammeli Liikkanen, Janne Sinkkonen, Joni Suorsa, Valtteri Kaasinen, Eero Pekkonen, Mikko Kärppä, Filip Scheperjans, Teppo Huttunen, Toni Sarapohja, Ullamari Pesonen, Mikko Kuoppamäki, Tapani Keränen
Publikováno v: PLOS Digital Health, Vol 2, Iss 4, p e0000225 (2023)
In the quantification of symptoms of Parkinson's disease (PD), healthcare professional assessments, patient reported outcomes (PRO), and medical device grade wearables are currently used. Recently, also commercially available smartphones and wearable
Externí odkaz: https://doaj.org/article/012d6c5856004986a94efd8d4883e5a0
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9
The effect of photocatalytic coatings on microbial attachment in brewery field tests
Autor: Storgårds, Erna, Priha, Outi, Laakso, J., Tapani, K., Levänen, E., Mäntylä, T.
Publikováno v: Storgårds, E, Priha, O, Laakso, J, Tapani, K, Levänen, E & Mäntylä, T 2011, ' The effect of photocatalytic coatings on microbial attachment in brewery field tests ', Paper presented at Photocatalytic and Superhydrophilic Surfaces Workshop, PSS2011, Manchester, United Kingdom, 12/09/11 .
Photocatalytic coatings have been reported to improve cleanability of surfaces and reduce bacterial attachment1,2,3. Only field tests, however, will eventually reveal their effect in industrial applications. Field tests cannot replace standardised la
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=355e65625b88::9b6f3a63529edc96055719a6815dfee6
https://cris.vtt.fi/en/publications/d20a2c9f-4057-4113-9a9a-f11eb1365034
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10
The effect of photocatalytic and low energy coatings on brewery surface microbes
Autor: Priha, Outi, Laakso, J., Tapani, K., Levänen, E., Kolari, M., Mäntylä, T., Storgårds, Erna
Publikováno v: Priha, O, Laakso, J, Tapani, K, Levänen, E, Kolari, M, Mäntylä, T & Storgårds, E 2010, ' The effect of photocatalytic and low energy coatings on brewery surface microbes ', Paper presented at 1st International Conference on Antimicrobial Research, ICAR2010, Valladolid, Spain, 3/11/10-5/11/10 .
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=355e65625b88::d6b3cda4dd124f47bcb00a37b49cd485
https://cris.vtt.fi/en/publications/3ec681e4-4cf5-47c2-a2b9-aaae3ea2105d
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