Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Tapan, Kanai"'
Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA
Autor:
Atanu Maiti, Wazo Myint, Tapan Kanai, Krista Delviks-Frankenberry, Christina Sierra Rodriguez, Vinay K. Pathak, Celia A. Schiffer, Hiroshi Matsuo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
APOBEC3G (A3G) is a single-stranded DNA (ssDNA) cytidine deaminase that restricts HIV-1. Here the authors provide molecular insights into A3G substrate recognition by determining the 1.86 Å resolution crystal structure of its catalytic domain bound
Externí odkaz:
https://doaj.org/article/ad6fc6963a274de1870dee1e6dd27792
Autor:
D. Thirumoolan, K. Anver Basha, Tapan Kanai, S. Mohammed Safiullah, K. Vetrivel, K. Abdul Wasi, B. Ranjithkumar
Publikováno v:
Journal of Saudi Chemical Society, Vol 20, Iss 2, Pp 195-200 (2016)
The methacrylamide monomer, N-(p-bromophenyl)-2-methacrylamide (PBPMA) was synthesized by reacting p-bromoaniline dissolved in ethylmethylketone (EMK) with methacryloyl chloride in the presence of triethylamine. The copolymers of PBPMA with N-Vinyl-2
Externí odkaz:
https://doaj.org/article/f3d0ac38daee444c8e17aefe20cfc369
Autor:
John F Andersen, Haotian Lei, Ethan C. Strayer, Tapan Kanai, Van Pham, Xiang-Zuo Pan, Patricia Hessab Alvarenga, Gloria F Gerber, Oluwatoyin A Asojo, Ivo M Francischetti, Robert A. Brodsky, Jesus G Valenzuela, Jose Ribeiro
Publikováno v:
Blood.
Inhibitors of complement and coagulation are present in the saliva of a variety of blood feeding arthropods that transmit parasitic and viral pathogens. Here we describe the structure and mechanism of action of the sand fly salivary protein lufaxin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5509228df94636e33ced80740148acfd
https://doi.org/10.1182/blood.2022019359
https://doi.org/10.1182/blood.2022019359
Autor:
Tapan Kanai, Zongyi Hu, Renbin Yang, Weimin Wu, Ziqiu Wang, Christopher D. Ma, Jaime Sanchez-Meza, Mansun Law, Michael Houghton, John Lokman Law, Michael Logan, Natalia de Val, T. Jake Liang
Publikováno v:
J Virol
Despite the development of highly effective hepatitis C virus (HCV) treatments, an effective prophylactic vaccine is still lacking. HCV infection is mediated by its envelope glycoproteins, E1 and E2, during the entry process, with E2 binding to cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b0adc409d8266a8115689f17963387
https://europepmc.org/articles/PMC9888182/
https://europepmc.org/articles/PMC9888182/
Autor:
Tapan Kanai, Asit B. Samui
Publikováno v:
International Journal of Biological Macromolecules. 140:522-537
Polyhydroxyalkanoates (PHAs) belong to a family of natural polyesters and are produced under unbalanced growth conditions as intracellular carbon and energy reserves by a wide variety of microorganisms. Being biodegradable, biocompatible and environm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85fb593af0ab27032c75b630ad0f394f
https://doi.org/10.1016/j.ijbiomac.2019.08.147
https://doi.org/10.1016/j.ijbiomac.2019.08.147
Autor:
Celia A. Schiffer, Shurong Hou, Nese Kurt Yilmaz, Wazo Myint, William C. Solomon, Hiroshi Matsuo, Tapan Kanai, Rashmi Tripathi
Publikováno v:
Nucleic Acids Research
The potent antiretroviral protein APOBEC3G (A3G) specifically targets and deaminates deoxycytidine nucleotides, generating deoxyuridine, in single stranded DNA (ssDNA) intermediates produced during HIV replication. A non-catalytic domain in A3G binds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ce852c6d9dc5336f033d7f2f085f7a
https://doi.org/10.1093/nar/gkz550
https://doi.org/10.1093/nar/gkz550
Autor:
Anu, Puri, Faisal, Ibrahim, André, O'Reilly Beringhs, Camryn, Isemann, Paul, Zakrevsky, Abigail, Whittenburg, Derek, Hargrove, Tapan, Kanai, Rebecca S, Dillard, Natalia, de Val, Michael H, Nantz, Xiuling, Lu, Bruce A, Shapiro
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 44:102572
We previously reported that hydroxylated oxime ether lipids (OELs) efficiently deliver functional Dicer substrate siRNAs (DsiRNAs) in cells. Here, we explored in vivo utility of these OELs, using OEL4 as a prototype and report that surface modificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c6e60fd4818d9385be651b822f84c4
https://doi.org/10.1016/j.nano.2022.102572
https://doi.org/10.1016/j.nano.2022.102572
Autor:
Daniel Arango, David Sturgill, Renbin Yang, Tapan Kanai, Paulina Bauer, Jyoti Roy, Ziqiu Wang, Masaki Hosogane, Sarah Schiffers, Shalini Oberdoerffer
Publikováno v:
Mol Cell
mRNA function is influenced by modifications that modulate canonical nucleobase behavior. We show that a single modification mediates distinct impacts on mRNA translation in a position-dependent manner. Although cytidine acetylation (ac4C) within pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c07e00864a8574d34f78a393f77cbb
https://doi.org/10.1016/j.molcel.2022.05.016
https://doi.org/10.1016/j.molcel.2022.05.016
Autor:
Nese Kurt Yilmaz, Rashmi Tripathi, Shurong Hou, Wazo Myint, Hiroshi Matsuo, Christina Sierra Rodriguez, Vinay K. Pathak, Krista A. Delviks-Frankenberry, Vanivilasini Balachandran, Atanu Maiti, Celia A. Schiffer, Tapan Kanai
Publikováno v:
J Mol Biol
APOBEC3G (A3G) is a single-stranded DNA (ssDNA) cytosine deaminase that can restrict HIV-1 infection by mutating the viral genome. A3G consists of a non-catalytic N-terminal domain (NTD) and a catalytic C-terminal domain (CTD) connected by a short li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348b386bee6f1275ca4f2879165b9099
https://pubmed.ncbi.nlm.nih.gov/33098858
https://pubmed.ncbi.nlm.nih.gov/33098858
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2fd68c2aede0e8c7c8a1c263d89fee3
https://doi.org/10.1096/fasebj.2019.33.1_supplement.493.9
https://doi.org/10.1096/fasebj.2019.33.1_supplement.493.9