Výsledky vyhledávání

Akademický článek

Analysis of the pharmacokinetics and efficacy of RBD1016 – A GalNAc-siRNA targeting Hepatitis B Virus X gene using semi-mechanistic PK/PD model

Autor: Qian Li, Taohua Geng, Haiyan Li, Shuquan Zheng, Sara Svedlund, Liming Gan, Ann-Charlotte Egnell, Shan Gao, Rui Chen, Pei Hu

Publikováno v: Heliyon, Vol 10, Iss 11, Pp e31924- (2024)

Small interference RNA (siRNA) is a class of short double-stranded RNA molecules that cause mRNA degradation through an RNA interference mechanism and is a promising therapeutic modality. RBD1016 is a siRNA drug in clinical development for the treatm

Externí odkaz: https://doaj.org/article/6797ab69ec9547f5891b25d823ad80a4

Zobrazit plný text záznamu

Pharmacokinetic profile of cefbuperazone in healthy Chinese volunteers after single and multiple drip intravenous infusion by HPLC-MS/MS

Autor: Taohua Geng, Li Ding, Yiya Wang, Dongbo Liu

Publikováno v: Journal of pharmaceutical and biomedical analysis. 129

A selective and reproducible HPLC–MS/MS method was developed and fully validated for the determination of cefbuperazone in human plasma and urine. Samples were prepared using protein precipitation and separated on a Zorbax Eclipse Plus C18 column (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28b4a6806187d4b938048dca46c92e0
https://pubmed.ncbi.nlm.nih.gov/27394175

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání