Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Tao Osgood"'
Autor:
Cong Li, Gregory Moore, Umesh Muchhal, John Desjarlais, Matthew Bernett, Madeline Fort, Lingming Liang, Tao Osgood, Rodolfo Yabut, Sarav Kaliyaperumal, John Harrold, Jude Canon, Anna Rogojina, Raushan Kurmasheva, Peter Houghton, Olivier Nolan-Stevaux
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/9f44cfaebbde4a72a66c6cbe35d25b0b
Autor:
Robert Radinsky, Angela Coxon, Jonathan D. Oliner, Richard Kendall, Stephen Kaufman, David Cordover, Jing Zhou, Ada Chen, Lixia Jin, Qiuping Ye, John Eksterowicz, Dongyin Yu, Rebecca Robertson, Anne Y. Saiki, Steven H. Olson, Tao Osgood, Jude Canon
Supplemental Figure 2. AMG 232 treatment causes p53 stabilization, and increased p21 and MDM2 proteins in p53 wild-type cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ec4ed1227e54787b7b9b848e7054f8
https://doi.org/10.1158/1535-7163.22502251
https://doi.org/10.1158/1535-7163.22502251
Autor:
Robert Radinsky, Angela Coxon, Jonathan D. Oliner, Richard Kendall, Stephen Kaufman, David Cordover, Jing Zhou, Ada Chen, Lixia Jin, Qiuping Ye, John Eksterowicz, Dongyin Yu, Rebecca Robertson, Anne Y. Saiki, Steven H. Olson, Tao Osgood, Jude Canon
Supplemental Figure 3. Body weights of mice in xenograft efficacy studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70094c78459d3b06c7a39847cc4f95b7
https://doi.org/10.1158/1535-7163.22502248
https://doi.org/10.1158/1535-7163.22502248
Autor:
Robert Radinsky, Angela Coxon, Jonathan D. Oliner, Richard Kendall, Stephen Kaufman, David Cordover, Jing Zhou, Ada Chen, Lixia Jin, Qiuping Ye, John Eksterowicz, Dongyin Yu, Rebecca Robertson, Anne Y. Saiki, Steven H. Olson, Tao Osgood, Jude Canon
Supplemental Figure 1. AMG 232 chemical structure, and 3-D model of AMG 232 bound to MDM2 protein.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237c3d9b93b8489d5f776c2f621275e8
https://doi.org/10.1158/1535-7163.22502254
https://doi.org/10.1158/1535-7163.22502254
Autor:
Isabelle Dussault, Teresa L. Burgess, April Chen, Jasmine Lin, Tae-Seong Kim, Monica Reese, Angela Coxon, Bethany Mattson, Tao Osgood, Jodi Moriguchi, Yajing Yang, Karen Rex, Paula J. Kaplan-Lefko, Yihong Zhang
Supplementary Figure 2 from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff5b68c2f33bab4e447df1a0a406bf0
https://doi.org/10.1158/0008-5472.22374507
https://doi.org/10.1158/0008-5472.22374507
Autor:
Isabelle Dussault, Teresa L. Burgess, April Chen, Jasmine Lin, Tae-Seong Kim, Monica Reese, Angela Coxon, Bethany Mattson, Tao Osgood, Jodi Moriguchi, Yajing Yang, Karen Rex, Paula J. Kaplan-Lefko, Yihong Zhang
Supplementary Figure 1 from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5996db34e4951571098f87ee3be5349a
https://doi.org/10.1158/0008-5472.22374510.v1
https://doi.org/10.1158/0008-5472.22374510.v1
Autor:
Isabelle Dussault, Teresa L. Burgess, April Chen, Jasmine Lin, Tae-Seong Kim, Monica Reese, Angela Coxon, Bethany Mattson, Tao Osgood, Jodi Moriguchi, Yajing Yang, Karen Rex, Paula J. Kaplan-Lefko, Yihong Zhang
Recepteur d'origine nantais (RON) is a receptor tyrosine kinase closely related to c-Met. Both receptors are involved in cell proliferation, migration, and invasion, and there is evidence that both are deregulated in cancer. Receptor overexpression h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::693dbc243ebea5d3b07a284750f8438b
https://doi.org/10.1158/0008-5472.c.6497475
https://doi.org/10.1158/0008-5472.c.6497475
Autor:
Isabelle Dussault, Teresa L. Burgess, April Chen, Jasmine Lin, Tae-Seong Kim, Monica Reese, Angela Coxon, Bethany Mattson, Tao Osgood, Jodi Moriguchi, Yajing Yang, Karen Rex, Paula J. Kaplan-Lefko, Yihong Zhang
Supplementary Figure Legends 1-3 from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b41e11498f2c9e7da1b2ffd7c1033be
https://doi.org/10.1158/0008-5472.22374501.v1
https://doi.org/10.1158/0008-5472.22374501.v1
Autor:
Isabelle Dussault, Teresa L. Burgess, April Chen, Jasmine Lin, Tae-Seong Kim, Monica Reese, Angela Coxon, Bethany Mattson, Tao Osgood, Jodi Moriguchi, Yajing Yang, Karen Rex, Paula J. Kaplan-Lefko, Yihong Zhang
Supplementary Figure 3 from Identification of a Novel Recepteur d'Origine Nantais/c-Met Small-Molecule Kinase Inhibitor with Antitumor Activity In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fcf47dcbf1f6b8c65582aa4fed4ad10
https://doi.org/10.1158/0008-5472.22374504.v1
https://doi.org/10.1158/0008-5472.22374504.v1
Autor:
Timothy J. Price, Victor J. Cee, Tisha San Miguel, Gerald Steven Falchook, Jonathan Werner, Christopher Mohr, Tao Osgood, James Kuo, Kevin Gaida, Xiaochun Zhu, Karen Rex, John D. McCarter, Brian A. Lanman, H. Henary, Roberto Ortiz, Ramaswamy Govindan, Tara Arvedson, Laurie P. Volak, Wenjun Ouyang, J. Russell Lipford, Tyler Holt, Charles G. Knutson, Neelima Koppada, David S. Hong, Aaron S. Rapaport, Anne Y. Saiki, Bert H. O'Neil, Jude Canon, Ji Rong Sun, Marwan Fakih, Brett E. Houk, Dhanashri Bagal, Keegan Cooke, Jayesh Desai
Publikováno v:
Nature. 575:217-223
KRAS is the most frequently mutated oncogene in cancer and encodes a key signalling protein in tumours1,2. The KRAS(G12C) mutant has a cysteine residue that has been exploited to design covalent inhibitors that have promising preclinical activity3–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4f8225bc18280b2cad72495f7029f3a
https://doi.org/10.1038/s41586-019-1694-1
https://doi.org/10.1038/s41586-019-1694-1