Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Tao G. Dong"'
Autor:
Li Song, Junfeng Pan, Yantao Yang, Zhenxing Zhang, Rui Cui, Shuangkai Jia, Zhuo Wang, Changxing Yang, Lei Xu, Tao G. Dong, Yao Wang, Xihui Shen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Bacteria can use type VI secretion systems (T6SSs) to inject toxic effector proteins into adjacent cells, in a contact-dependent manner. Here, the authors provide evidence of contact-independent killing by a T6SS effector that is secreted into the ex
Externí odkaz:
https://doaj.org/article/bd3021c8f83042c48889bf3646238a2f
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The molecular mechanisms by which the sheath-tube of the bacterial type VI secretion system assembles are not fully understood. Here, the authors present evidence that the priming of the sheath-tube is controlled by TssA–TssM–TagA in Vibrio chole
Externí odkaz:
https://doaj.org/article/e02eeac85679463889bd0f7e46095d14
Autor:
Tong-Tong Pei, Hao Li, Xiaoye Liang, Zeng-Hang Wang, Guangfeng Liu, Li-Li Wu, Haeun Kim, Zhiping Xie, Ming Yu, Shuangjun Lin, Ping Xu, Tao G. Dong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Bacterial Rhs proteins with toxic domains are often secreted by type VI secretion systems. Here, the authors show that one of these proteins self-cleaves into three fragments, with the Rhs core and the N-terminal domain facilitating secretion and fun
Externí odkaz:
https://doaj.org/article/1410ae66c5d64cf8a5d2058c700ddb6e
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT Antimicrobial resistance (AMR) has become a serious public and economic threat. The rate of bacteria acquiring AMR surpasses the rate of new antibiotics discovery, projecting more deadly AMR infections in the future. The Pathogen Box is an o
Externí odkaz:
https://doaj.org/article/c660b948f543459d970eb5036b75fc47
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Genetic editing has revolutionized biotechnology, but delivery of endonuclease genes as DNA can lead to aberrant integration or overexpression, leading to off-target effects. Here, we develop a mechanism to deliver Cre recombinase as a prote
Externí odkaz:
https://doaj.org/article/d3308ab0e6ee467d9e941b6894a76881
Autor:
Fatima Kamal, Xiaoye Liang, Kevin Manera, Tong-Tong Pei, Haeun Kim, Linh G. Lam, Alexander Pun, Steven J. Hersch, Tao G. Dong
Publikováno v:
Cell Reports, Vol 31, Iss 11, Pp 107766- (2020)
Summary: The type VI secretion system (T6SS) is a lethal microbial weapon that injects a large needle-like structure carrying toxic effectors into recipient cells through physical penetration. How recipients respond to physical force and effectors re
Externí odkaz:
https://doaj.org/article/6280700611004731bff2a4b70673961c
Autor:
Meiru Si, Yao Wang, Bing Zhang, Chao Zhao, Yiwen Kang, Haonan Bai, Dawei Wei, Lingfang Zhu, Lei Zhang, Tao G. Dong, Xihui Shen
Publikováno v:
Cell Reports, Vol 20, Iss 4, Pp 949-959 (2017)
The type VI secretion system was recently reported to be involved in zinc acquisition, but the underlying mechanism remains unclear. Here, we report that Burkholderia thailandensis T6SS4 is involved in zinc acquisition via secretion of a zinc-scaveng
Externí odkaz:
https://doaj.org/article/2ddac0070bc3415c993faef3a8bba184
Autor:
Tong-Tong Pei, Hao Li, Xiaoye Liang, Zeng-Hang Wang, Guangfeng Liu, Li-Li Wu, Haeun Kim, Zhiping Xie, Ming Yu, Shuangjun Lin, Ping Xu, Tao G. Dong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/eb816676343d44898d4126ea7946c4aa
Publikováno v:
Cellulose. 29:9341-9360
Publikováno v:
The FEBS Journal. 289:4704-4717
Equipped with a plethora of secreted toxic effectors, protein secretion systems are essential for bacteria to interact with and manipulate their neighboring environment to survive in host microbiota and other highly competitive communities. While eff