Zobrazeno 1 - 10
of 279
pro vyhledávání: '"Tao‐Sheng Li"'
Autor:
Cong Ye, Chen Yan, Si-Jia Bian, Xin-Ran Li, Yu Li, Kai-Xuan Wang, Yu-Hua Zhu, Liang Wang, Ying-Chao Wang, Yi-Yuan Wang, Tao-Sheng Li, Su-Hua Qi, Lan Luo
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Doxorubicin (DOX) is a first-line chemotherapeutic drug for various malignancies that causes cardiotoxicity. Plant-derived exosome-like nanovesicles (P-ELNs) are growing as novel therapeutic agents. Here, we investigated the prote
Externí odkaz:
https://doaj.org/article/978f4aae8bd64db2bedcf53067529f86
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Replication stress is a major contributor to tumorigenesis because it provides a source of chromosomal rearrangements via recombination events. PARK2, which encodes parkin, a regulator of mitochondrial homeostasis, is located on one of the c
Externí odkaz:
https://doaj.org/article/5f37204c6fe149ec973d154bf659e491
Autor:
Yong Xu, Yu Li, Da Zhai, Chen Yan, Jingyan Liang, Taiga Ichinomiya, Tetsuya Hara, Chiaki Inadomi, Tao-Sheng Li
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Mechanical ventilation is a supportive therapy used to maintain respiratory function in several clinical and surgical cases but is always accompanied by lung injury risk due to improper treatment. We investigated how tidal volume
Externí odkaz:
https://doaj.org/article/d9f0d6b1ec5d4c07975d07518b508706
Elevated hydrostatic pressure disturbs expression of growth factors in human renal epithelial cells.
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0310001 (2024)
Obstructive uropathy is a common kidney disease caused by elevated hydrostatic pressure (HP), but relevant molecular and cellular mechanisms have not yet been well understood. In this study, we ex vivo investigated the effects of elevated HP on human
Externí odkaz:
https://doaj.org/article/1e71f56f649f4c2fbb2e26a928c18cdb
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0300548 (2024)
Biomechanical cue within the tissue microenvironment is known to play a critical role in regulating cell behaviors and maintaining tissue homeostasis. As hydrostatic pressure often increases in biliary system under pathological states, we investigate
Externí odkaz:
https://doaj.org/article/b8760f8241a54e11b892230d9a95ddd8
Autor:
Ge Zhang, Zaoqu Liu, Jinhai Deng, Long Liu, Yu Li, Siyuan Weng, Chunguang Guo, Zhaokai Zhou, Li Zhang, Xiaofang Wang, Gangqiong Liu, Jiacheng Guo, Jing Bai, Yunzhe Wang, Youyou Du, Tao-Sheng Li, Junnan Tang, Jinying Zhang
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background Mounting evidence has revealed the dynamic variations in the cellular status and phenotype of the smooth muscle cell (SMC) are vital for shaping the atherosclerotic plaque microenvironment and ultimately mapping onto heterogeneous
Externí odkaz:
https://doaj.org/article/22cea45a710d4df4bb4f5b1d10a06ade
Autor:
Satoshi Mizoguchi, Tomoshi Tsuchiya, Ryoichiro Doi, Tomohiro Obata, Mayumi Iwatake, Shintaro Hashimoto, Hirotaka Matsumoto, Hiroshi Yukawa, Hiroko Hayashi, Tao-Sheng Li, Kazuko Yamamoto, Keitaro Matsumoto, Takuro Miyazaki, Koichi Tomoshige, Takeshi Nagayasu
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Two-dimensional cell cultures have contributed substantially to lung cancer research, but 3D cultures are gaining attention as a new, more efficient, and effective research model. A model reproducing the 3D characteristics and tumor mic
Externí odkaz:
https://doaj.org/article/ee7d56c1f8b447fb85441f9dfff0f0f4
Publikováno v:
FEBS Open Bio, Vol 12, Iss 6, Pp 1230-1240 (2022)
Elevated interstitial fluid hydrostatic pressure is commonly observed in diseased livers. We herein examined the hypothesis that hydrostatic pressure induces hepatic stellate cells to acquire profibrotic properties under pathological conditions. Huma
Externí odkaz:
https://doaj.org/article/406b3060e6f74394b1795353240ef928
Publikováno v:
Translational Oncology, Vol 26, Iss , Pp 101548- (2022)
The PARP-1 expression level and poly (ADP-ribosyl)ation activity in cancer markedly affect the therapeutic outcome. Nicaraven, a free radical scavenger has been found to inhibit PARP, but the effect on cancer cells is still unclear. In this study, we
Externí odkaz:
https://doaj.org/article/8213ee5543444a39a9d27fc7c001b22d
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 16 (2022)
Objective: Radiation-induced lung injury (RILI) is one of the serious complications of radiotherapy. We have recently demonstrated that nicaraven can effectively mitigate RILI in healthy mice. Here, we further tried to optimize the dose and time of n
Externí odkaz:
https://doaj.org/article/9426339e57d14805b96f53e3d5813a83