Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tanzina Mollick"'
Autor:
Tanzina Mollick, Suhas Darekar, Basile Dalarun, Flavia Plastino, Juan Zhang, Andres Pastor Fernández, Twana Alkasalias, Helder André, Sonia Laín
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23831- (2024)
Retinoblastoma is an eye cancer that commonly affects young children. Despite significant advances, current treatments cause side effects even when administered locally, and patients may still have to undergo enucleation. This is particularly dishear
Externí odkaz:
https://doaj.org/article/c582d86aa6a9459dbb5b0bce5058ee33
Autor:
Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/0c0c030dc1c54c61a794787a99cca008
Autor:
Tanzina Mollick, Sonia Laín
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-11 (2020)
Abstract By providing the necessary building blocks for nucleic acids and precursors for cell membrane synthesis, pyrimidine ribonucleotides are essential for cell growth and proliferation. Therefore, depleting pyrimidine ribonucleotide pools has lon
Externí odkaz:
https://doaj.org/article/5a8ebb3532ba453cbf0f70406ae9d352
Autor:
Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Abstract The development of non-genotoxic therapies that activate wild-type p53 in tumors is of great interest since the discovery of p53 as a tumor suppressor. Here we report the identification of over 100 small-molecules activating p53 in cells. We
Externí odkaz:
https://doaj.org/article/c70bab1df6ec4076bb2c93aa455abeeb
Autor:
Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)
The original PDF version of this Article listed the authors as “Marcus J.G.W. Ladds,” where it should have read “Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond et al.#”. Also in the PDF version, it was incorrectly st
Externí odkaz:
https://doaj.org/article/6b88c0d66cd64b709fb079a6627015c7
Autor:
Karin Larsson, Tanzina Mollick, Richard Svensson, Mireia Mayoral Safont, Emma M. Peat, Yan Zhao, Anna Lena Gustavsson, Chloe Tuck, David P. Lane, Gergana Popova, Anna R. McCarthy, Katarina Färnegårdh, Maureen Higgins, John Lunec, Ulrika Yngve, Marcus J.G.W. Ladds, Andrés Pastor Fernández, Nicholas J. Westwood, Emmet McCormack, Alan R. Healy, Ingeborg M.M. van Leeuwen, Suhas Darekar, Catherine J. Drummond, Martin Haraldsson, Pascal Gelebart, Mihaela Popa, Marijke C.C. Sachweh, Lars Johansson, Sonia Lain, Ravi Bhatia, Zinayida Fandalyuk, Vicent Pelechano, Agathe C.A. D'Hollander, Borivoj Vojtesek, Su Chu, Mar Carmena, William C. Earnshaw, Alastair M. Thompson, Saikiran K. Sedimbi, Marta Nekulova, Maria Håkansson, Aljona Saleh, Marie Arsenian-Henriksson, Johanna Campbell, Marcela Franco, Björn Walse
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Ladds, M J G W, van Leeuwen, I M M, Drummond, C J, Chu, S, Healy, A R, Popova, G, Pastor Fernández, A, Mollick, T, Darekar, S, Sedimbi, S K, Nekulova, M, Sachweh, M C C, Campbell, J, Higgins, M, Tuck, C, Popa, M, Safont, M M, Gelebart, P, Fandalyuk, Z, Thompson, A M, Svensson, R, Gustavsson, A-L, Johansson, L, Färnegårdh, K, Yngve, U, Saleh, A, Haraldsson, M, D'Hollander, A C A, Franco, M, Zhao, Y, Håkansson, M, Walse, B, Larsson, K, Peat, E M, Pelechano, V, Lunec, J, Vojtesek, B, Carmena, M, Earnshaw, W C, McCarthy, A R, Westwood, N J, Arsenian-Henriksson, M, Lane, D P, Bhatia, R, McCormack, E & Laín, S 2018, ' A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage ', Nature Communications, vol. 9, no. 1, 1107 (2018) . https://doi.org/10.1038/s41467-018-03441-3
Nature Communications
Ladds, M J G W, van Leeuwen, I M M, Drummond, C J, Chu, S, Healy, A R, Popova, G, Pastor Fernández, A, Mollick, T, Darekar, S, Sedimbi, S K, Nekulova, M, Sachweh, M C C, Campbell, J, Higgins, M, Tuck, C, Popa, M, Safont, M M, Gelebart, P, Fandalyuk, Z, Thompson, A M, Svensson, R, Gustavsson, A-L, Johansson, L, Färnegårdh, K, Yngve, U, Saleh, A, Haraldsson, M, D'Hollander, A C A, Franco, M, Zhao, Y, Håkansson, M, Walse, B, Larsson, K, Peat, E M, Pelechano, V, Lunec, J, Vojtesek, B, Carmena, M, Earnshaw, W C, McCarthy, A R, Westwood, N J, Arsenian-Henriksson, M, Lane, D P, Bhatia, R, McCormack, E & Laín, S 2018, ' A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage ', Nature Communications, vol. 9, no. 1, 1107 (2018) . https://doi.org/10.1038/s41467-018-03441-3
ML, CD, IvL, GP, TM, SD, MS, APF, CT, DL, MAH, KL and SL: project grants from the Swedish Research Council, the Swedish Cancer Society and the Swedish Childhood Cancer Foundation. MHi and JC: Cancer Research UK (C8/A6613). MC, EP and WE: Wellcome Tru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd2c01d2aabbdecaf13d8d9d9ac446c
http://link.springer.com/article/10.1038/s41467-018-03441-3
http://link.springer.com/article/10.1038/s41467-018-03441-3
Publikováno v:
Brain Research. 1646:522-534
Retinal neurodegenerative disorders like retinitis pigmentosa, age-related macular degeneration, diabetic retinopathy and retinal detachment decrease retinal functionality leading to visual impairment. The pathological events are characterized by pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d30f9c24b3faa2a0cc35415c6985b9
https://doi.org/10.1016/j.brainres.2016.06.039
https://doi.org/10.1016/j.brainres.2016.06.039
Autor:
Mireia Mayoral Safont, Björn Walse, Katarina Färnegårdh, Lars Johansson, Marie Arsenian-Henriksson, Pascal Gelebart, Alan R. Healy, Marijke C.C. Sachweh, Johanna Campbell, Marcela Franco, Marta Nekulova, Richard Svensson, Maria Håkansson, Tanzina Mollick, Borivoj Vojtesek, Emmet McCormack, Anna Lena Gustavsson, Yan Zhao, Mar Carmena, John Lunec, Aljona Saleh, Sonia Lain, Ravi Bhatia, Anna R. McCarthy, Marcus J.G.W. Ladds, Saikiran K. Sedimbi, Suhas Darekar, Catherine J. Drummond, Zinayida Fandalyuk, Agathe C.A. D'Hollander, Vicent Pelechano, Ulrika Yngve, Su Chu, Karin Larsson, Alastair M. Thompson, Ingeborg M.M. van Leeuwen, Chloe Tuck, Martin Haraldsson, Mihaela Popa, Emma M. Peat, Gergana Popova, Maureen Higgins, Andrés Pastor Fernández, Nicholas J. Westwood, William C. Earnshaw, David P. Lane
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)
The development of non-genotoxic therapies that activate wild-type p53 in tumors is of great interest since the discovery of p53 as a tumor suppressor. Here we report the identification of over 100 small-molecules activating p53 in cells. We elucidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d805f7ca635514dcfc03b4f3e80cf7d7
https://doi.org/10.1038/s41467-018-04198-5
https://doi.org/10.1038/s41467-018-04198-5
Publikováno v:
Neuroscience. 279:269-284
Interaction between pericytes and endothelial cells via platelet-derived growth factor B (PDGF-B) signaling is critical for the development of the retinal microvasculature. The PDGF-B retention motif controls the spatial distribution range of the gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465b86206b301e695920b2694d3f756c
https://doi.org/10.1016/j.neuroscience.2014.09.013
https://doi.org/10.1016/j.neuroscience.2014.09.013