Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tanzila, Arshad"'
Autor:
Tanzila Arshad, Hamdullah Khadim Sheikh, Mehdi Hassan Kazmi, Sadia Farheen, Tehmina Sohail, Mehreen Lateef
Publikováno v:
Bangladesh Journal of Pharmacology, Vol 13, Iss 4 (2018)
Four new bioactive aryl triester derivatives of glycerol and benzoic acids were synthesized. The synthetic compounds were studied for their antimicrobial and urease inhibition activities. Esterification was carried out by using carbonyldiimidazole to
Externí odkaz:
https://doaj.org/article/c5417dafe0454aed9d07cbf1bc98b677
Autor:
Hamdullah Khadim, Sheikh, Tanzila, Arshad, Uzma, Habib, Zainab Sher, Mohammad, Maaz Uddin, Ahmed Siddiqui, Mohtasheemul, Hassan
Publikováno v:
Pakistan journal of pharmaceutical sciences. 35(1)
Early and rapid detection of SARS-CoV-2 in an infected person is one fundamental part of the strategy against the spread of this virus. As of now, the usual practice is to carry out polymerase chain reaction (PCR) test which provides results in 24-48
Autor:
Hamdullah Khadim, Sheikh, Tanzila, Arshad, Zainab Sher, Mohammad, Isra Khalil, Moussa, Rafia, Usman, Muhammad Mohtasheemul, Hasan
Publikováno v:
Pakistan journal of pharmaceutical sciences. 33(5(Supplementary))
Here, new phenoxide derivatives of diisopropyl flourophosphate for reaction with Lewis basic sites on acetyl cholinesterase (AChE) were designed. Such binding interaction or reaction inhibits the hydrolysis of the acetylcholine (ACh) neurotransmitter
Autor:
Hamdullah Khadim, Sheikh, Tanzila, Arshad, Maria, Merajoddin, Zainab Sher, Mohammad, Rafia, Usman, Muhammad Mohtasheemul, Hasan
Publikováno v:
Pakistan journal of pharmaceutical sciences. 33(5)
In this research, molecular structural manipulation of treosulfan alkylating agent and resultant changes in binding is studied to assist in designing derivatives of treosulfan for synthesis. Molecular docking has been conducted on simulated heterocyc
Autor:
Mohtasheemul Hassan, Iqra Arshad, Zainab Sher Mohammad, Tanzila Arshad, Hamdullah Khadim Sheikh
In this research, structure of SARS-CoV-2 spike glycoprotein S1 and S2 along with TMPRSS2, TMPRSS4, TMPRSS11A, TMPRSS11D and TMPRSS11E serine protease (which activates S1 and S2) are used for docking with repurposed inhibitor drug molecules. We searc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b08f98d9cd50a256e1ff1d852809b478
https://doi.org/10.26434/chemrxiv.12192660
https://doi.org/10.26434/chemrxiv.12192660
Autor:
Mohtasheemul Hassan, Iqra Arshad, Hamdullah Khadim Sheikh, Zainab Sher Mohammad, Tanzila Arshad
In this research we used the structure of SARS-CoV-2 related, recently mapped, atomic structure of nsp10/16 proteins for docking with some known drug molecular structures at pH 7 and 5. Chosen molecules were azo -N=N- and -COOH derivatives. It was re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20168e3f291efde6fe913a6b3ad3e7ca
https://doi.org/10.26434/chemrxiv.12026736.v1
https://doi.org/10.26434/chemrxiv.12026736.v1
Autor:
Mohtasheemul Hassan, Iqra Arshad, Zainab Sher Mohammad, Tanzila Arshad, Hamdullah Khadim Sheikh
In this research we used the structure of SARS-CoV-2 main protease (Mpro) for docking with Anti-HIV protease inhibitor drug molecules within pH 4-8. By carrying out the variance analysis of binding energies at pH 4-8, it was revealed that the binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93d0d495a712aaf476257bf6acbe3596
https://doi.org/10.26434/chemrxiv.12009018
https://doi.org/10.26434/chemrxiv.12009018
Autor:
Noshab, Qamar, Hira, Sultan, Ahmad, Raheel, Maria, Ashfaq, Rafia, Azmat, Raheela, Naz, Mehreen, Lateef, Khalid Mohammed, Khan, Tanzila, Arshad
Publikováno v:
Pakistan journal of pharmaceutical sciences. 32(3 (Supplementary))
The current article discusses the activities of several synthesized metal heterochelates in in-vitro as anti-ulcer agents followed by their docking study. For this purpose, two important ligands like 8-hydroxyquinoline and DL-methionine were used in
Autor:
Tanzila Arshad, Uzma Salar, Muhammad Riaz, Abdul Wadood, Khalid Mohammed Khan, Muhammad Taha, Shafqat Hussain, Shahnaz Perveen, Mohammed Ashraf, Najma Rasool, Tehreem Tahir, Nor Hadiani Ismail
Publikováno v:
Medicinal Chemistry Research. 25:2058-2069
Based on the previous reports on α-glucosidase inhibitory activity of benzimidazole class, we intend to evaluate further this class as potential inhibitors of α-glucosidase enzyme. Thus, in the current study synthesis of 5-bromo-2-aryl benzimidazol
Publikováno v:
Pakistan journal of pharmaceutical sciences. 31(3(Supplementary))
This research work revolves around synthesis of antineoplastic alkylating sulfonate esters with dual alkylating sites for crosslinking of the DNA strands. These molecules were evaluated as potential antineoplastic cross linking alkylating agents by r