Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tanya T. Marar"'
Autor:
Tanya T. Marar, Michael B. Boffa
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 4, Pp 102459- (2024)
Background: Thrombin-activatable fibrinolysis inhibitor (TAFI) is a plasma zymogen that provides a molecular link between coagulation and fibrinolysis. Studies have shown that the presence of glycosaminoglycans accelerates TAFI activation by plasmin
Externí odkaz:
https://doaj.org/article/59776a219b4f4a478e2b2425bf0564b5
Autor:
Michael B. Boffa, Tanya T. Marar, Calvin Yeang, Nicholas J. Viney, Shuting Xia, Joseph L. Witztum, Marlys L. Koschinsky, Sotirios Tsimikas
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 12, Pp 2082-2089 (2019)
It is postulated that lipoprotein (a) [Lp(a)] inhibits fibrinolysis, but this hypothesis has not been tested in humans due to the lack of specific Lp(a) lowering agents. Patients with elevated Lp(a) were randomized to antisense oligonucleotide [IONIS
Externí odkaz:
https://doaj.org/article/28dfa1e214734075affad1972af7235c
Autor:
Calvin Yeang, Marlys L. Koschinsky, Nicholas J. Viney, Joseph L. Witztum, Sotirios Tsimikas, Tanya T. Marar, Shuting Xia, Michael B. Boffa
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 12, Pp 2082-2089 (2019)
J Lipid Res
Journal of lipid research, vol 60, iss 12
J Lipid Res
Journal of lipid research, vol 60, iss 12
It is postulated that lipoprotein (a) [Lp(a)] inhibits fibrinolysis, but this hypothesis has not been tested in humans due to the lack of specific Lp(a) lowering agents. Patients with elevated Lp(a) were randomized to antisense oligonucleotide [IONIS
Autor:
Tanya T. Marar, Chelsea N. Matzko, Jie Wu, Charles T. Esmon, Talid Sinno, Lawrence F. Brass, Timothy J. Stalker, Maurizio Tomaiuolo
Publikováno v:
Blood
Rebalancing the hemostatic system by targeting endogenous anticoagulant pathways, like the protein C (PC) system, is being tested as a means of improving hemostasis in patients with hemophilia. Recent intravital studies of hemostasis demonstrated tha
Autor:
Nicholas D. Martinez, Amy E Siebert, Tanya T Marar, Sinny Delacroix, Timothy J. Stalker, Jie Wu, Maurizio Tomaiuolo, Robert D. Simari, Lawrence F. Brass, Alan E. Mast, Susan A. Maroney
Publikováno v:
J Thromb Haemost
BACKGROUND: Tissue factor pathway inhibitor (TFPI) is an essential regulator of coagulation, limiting thrombin generation and preventing thrombosis. In humans and mice, TFPIα is the sole isoform present in platelets. OBJECTIVE: Here, we asked whethe