Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tanya Sokolsky"'
Autor:
Richard B. Parad, Stephen G. Kaler, Evan Mauceli, Tanya Sokolsky, Ling Yi, Arindam Bhattacharjee
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 24, Iss , Pp 100625- (2020)
Purpose: Population-based newborn screening (NBS) allows early detection and treatment of inherited disorders. For certain medically-actionable conditions, however, NBS is limited by the absence of reliable biochemical signatures amenable to detectio
Externí odkaz:
https://doaj.org/article/eccee17972114816b93ef2a68be4fe70
Autor:
Arindam Bhattacharjee, Leslie Hammill, Becky Kitchener, Viren R. Amin, Marine Bellucci, Tanya Sokolsky
Publikováno v:
Journal of Obstetric, Gynecologic & Neonatal Nursing. 49:S74-S75
Autor:
Tania A. Baker, Tanya Sokolsky
Publikováno v:
Molecular Microbiology. 47:397-409
The MuA transposase mediates transposition of bacteriophage Mu through two distinct mechanisms. The first integration event following infection occurs through a non-replicative mechanism. In contrast, during lytic growth, multiple rounds of replicati
Autor:
Stacia K. Wyman, Holmes Morton, Erik G. Puffenberger, Edwin W. Naylor, Kevin A. Strauss, Richard B. Parad, Tanya Sokolsky, Martin G. Reese, Arindam Bhattacharjee
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics. 17(5)
Genetic testing is routinely used for second-tier confirmation of newborn sequencing results to rule out false positives and to confirm diagnoses in newborns undergoing inpatient and outpatient care. We developed a targeted next-generation sequencing
Autor:
William J. Mileski, Rachel Kasinskas, Jonathan Schultz, Mohammad Alanjary, Jacqueline A. Fidanza, Bernard P. Puc, G. Thomas Roth, Annika Branting, Yutao Fu, John H. Leamon, Marina Sedova, Travis A. Clark, Tanya Sokolsky, Michael R. Lyons, Simon Cawley, Wolfgang Hinz, Alan Williams, Matthew D. Edwards, Xin Miao, John F. Davidson, Kevin McKernan, Jeremy Hoon, Eugeni Namsaraev, James Bustillo, Jan Fredrik Simons, Todd Rearick, Eileen T. Dimalanta, Isaac B. Stoner, Jonathan M. Rothberg, Erika Feierstein, David Marran, Jeffrey T. Branciforte, Devin Dressman, Mark James Milgrew, John Nobile, David Light, Martin Huber, Nils Homer, Michelle Schorn, Melville Davey, Brian Reed, Kim L. Johnson, Jeffrey Sabina, Jason W. Myers
Publikováno v:
Nature. 475(7356)
The seminal importance of DNA sequencing to the life sciences, biotechnology and medicine has driven the search for more scalable and lower-cost solutions. Here we describe a DNA sequencing technology in which scalable, low-cost semiconductor manufac
Autor:
Stephen F. McLaughlin, Martin G. Reese, Gina Costa, Francisco M. De La Vega, Cynthia L. Hendrickson, Can Alkan, Joel A. Malek, Tanya Sokolsky, Andrew MacBride, Alena A. Antipova, Kathleen C. Hayashibara, Zheng Zhang, Jonathan M. Manning, Alan Blanchard, Swati Ranade, Haoning Fu, Kevin McKernan, Adam Sannicandro, Damon S. Perez, Vineet Bafna, Jeremy R. Stuart, Michael P. Moore, Robert E. Beaudoin, Rajesh Gottimukkala, Yutao Fu, Lei Zhang, Eric F. Tsung, Andrew Sheridan, Cisyla Duncan, Ali Bashir, Fiona Hyland, Jeffrey M. Kidd, Jeffrey K. Ichikawa, Michael W. Laptewicz, Michael D. Rhodes, Brittany E. Coleman, Michael R. Lyons, Eileen T. Dimalanta, Clarence Lee, Shan Yang, Bin Li, Evan E. Eichler, Heather E. Peckham, Christopher Clouser, Lev Kotler
Publikováno v:
Genome research. 19(9)
We describe the genome sequencing of an anonymous individual of African origin using a novel ligation-based sequencing assay that enables a unique form of error correction that improves the raw accuracy of the aligned reads to >99.9%, allowing us to
Autor:
Maitreya J. Dunham, Eduardo M. Torres, Tanya Sokolsky, Leon Y. Chan, Angelika Amon, Cheryl M. Tucker, Monica Boselli
Publikováno v:
Science (New York, N.Y.). 317(5840)
Aneuploidy is a condition frequently found in tumor cells, but its effect on cellular physiology is not known. We have characterized one aspect of aneuploidy: the gain of extra chromosomes. We created a collection of haploid yeast strains that each b
Publikováno v:
The Journal of biological chemistry. 274(23)
In yeast, MSH2 interacts with MSH6 to repair base pair mismatches and single nucleotide insertion/deletion mismatches and with MSH3 to recognize small loop insertion/deletion mismatches. We identified a msh6 mutation (msh6-F337A) that when overexpres
Autor:
Eric White, Kyusung Park, Jennifer M. Kilzer, Delia Ye, Tanya Sokolsky, Rob Bennett, Cisilya Duncan, Rhonda Meredith, Xiaoping Duan, Adam N. Harris
Publikováno v:
Cancer Research. 71:4851-4851
With the advent of second-generation sequencing technologies, exome- and transcriptome- and whole genome sequencing are tools of choice in studying cancer to detect alterations in the genome correlating with tumorigenesis. It is essential to compare