Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tanya Sezin"'
Autor:
Yask Gupta, Anna Lara Ernst, Artem Vorobyev, Foteini Beltsiou, Detlef Zillikens, Katja Bieber, Simone Sanna-Cherchi, Angela M. Christiano, Christian D. Sadik, Ralf J. Ludwig, Tanya Sezin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
In this study, 591 mice from an advanced-intercross mouse line were used to provide evidence that fungi are regulated by host genetics, while uncovering a regulatory role of diet on the composition of fungi in the murine gut.
Externí odkaz:
https://doaj.org/article/f9d4b29bc4eb41828406e434b6057330
Autor:
Zhenpeng Dai, Tanya Sezin, Yuqian Chang, Eunice Y. Lee, Eddy Hsi Chun Wang, Angela M. Christiano
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Alopecia areata (AA) is an autoimmune disease caused by T cell-mediated destruction of the hair follicle (HF). Therefore, approaches that effectively disrupt pathogenic T cell responses are predicted to have therapeutic benefit for AA treatment. T ce
Externí odkaz:
https://doaj.org/article/06ceda2989ab47ce85b4bd591af68703
Autor:
Hideyuki Ujiie, David Rosmarin, Michael P. Schön, Sonja Ständer, Katharina Boch, Martin Metz, Marcus Maurer, Diamant Thaci, Enno Schmidt, Connor Cole, Kyle T. Amber, Dario Didona, Michael Hertl, Andreas Recke, Hanna Graßhoff, Alexander Hackel, Anja Schumann, Gabriela Riemekasten, Katja Bieber, Gant Sprow, Joshua Dan, Detlef Zillikens, Tanya Sezin, Angela M. Christiano, Kerstin Wolk, Robert Sabat, Khalaf Kridin, Victoria P. Werth, Ralf J. Ludwig
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
An estimated 20–25% of the population is affected by chronic, non-communicable inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most frequent chronic inflammatory skin diseases are atopic dermatitis, psoriasis, urtic
Externí odkaz:
https://doaj.org/article/b4d49925740d40d997ea17caa001b46a
Autor:
Artem Vorobyev, Yask Gupta, Tanya Sezin, Hiroshi Koga, Yannic C. Bartsch, Meriem Belheouane, Sven Künzel, Christian Sina, Paul Schilf, Heiko Körber-Ahrens, Foteini Beltsiou, Anna Lara Ernst, Stanislav Khil’chenko, Hassanin Al-Aasam, Rudolf A. Manz, Sandra Diehl, Moritz Steinhaus, Joanna Jascholt, Phillip Kouki, Wolf-Henning Boehncke, Tanya N. Mayadas, Detlef Zillikens, Christian D. Sadik, Hiroshi Nishi, Marc Ehlers, Steffen Möller, Katja Bieber, John F. Baines, Saleh M. Ibrahim, Ralf J. Ludwig
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Complex traits associate with genetic variation and environment and their interaction. Here, the authors study the influence of different diets on trait variability in 1154 outbred mice from an advanced intercross line and find gene-diet interactions
Externí odkaz:
https://doaj.org/article/33aa09018c92411598dc61043de133d0
Autor:
Lina Jegodzinski, Tanya Sezin, Karin Loser, Sadegh Mousavi, Detlef Zillikens, Christian D. Sadik
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The G protein-coupled receptor 15 (GPR15) has recently been highlighted as an important regulator of T cell trafficking into the gut under physiological and pathophysiological conditions. Additionally, circumstantial evidence has accumulated that GPR
Externí odkaz:
https://doaj.org/article/7363bb0489ac4a849f6aed995a6d622a
Autor:
Tanya Sezin, Artem Vorobyev, Christian D. Sadik, Detlef Zillikens, Yask Gupta, Ralf J. Ludwig
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Pemphigus and systemic lupus erythematosus (SLE) are severe potentially life-threatening autoimmune diseases. They are classified as B-cell-mediated autoimmune diseases, both depending on autoreactive CD4+ T lymphocytes to modulate the autoimmune B-c
Externí odkaz:
https://doaj.org/article/2309f156f7b844b2bed8284778f73998
Autor:
George I. Austin, Heekuk Park, Yoli Meydan, Dwayne Seeram, Tanya Sezin, Yue Clare Lou, Brian A. Firek, Michael J. Morowitz, Jillian F. Banfield, Angela M. Christiano, Itsik Pe’er, Anne-Catrin Uhlemann, Liat Shenhav, Tal Korem
Publikováno v:
Nature Biotechnology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30f9a351508e32d073aee60b75242f44
https://doi.org/10.1038/s41587-023-01696-w
https://doi.org/10.1038/s41587-023-01696-w
Publikováno v:
The American Journal of Dermatopathology. 42:783-786
Neonatal autoimmune subepidermal blistering disease is rare. Mucosal involvement is more common in neonatal linear immunoglobulin A (IgA) bullous dermatosis. We describe a neonate with subepidermal cutaneous blistering disease with severe laryngeal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea79ed6890bbe22304b0310a5f8f6e5
https://doi.org/10.1097/dad.0000000000001700
https://doi.org/10.1097/dad.0000000000001700
Autor:
Sophia Kirschke, Ireti Ogunsulire, Balachandar Selvakumar, Neele Schumacher, Tanya Sezin, Stefan Rose-John, Alexander Scheffold, Christoph Garbers, Juliane Lokau
Publikováno v:
The Journal of biological chemistry. 298(6)
The cytokine interleukin-2 (IL-2) plays a critical role in controlling the immune homeostasis by regulating the proliferation and differentiation of immune cells, especially T cells. IL-2 signaling is mediated via the IL-2 receptor (IL-2R) complex, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ffc4c4e1cf834e927123f51d7374d00
https://pubmed.ncbi.nlm.nih.gov/35398356
https://pubmed.ncbi.nlm.nih.gov/35398356
Autor:
Sadegh Mousavi, Linda Kempen, Detlef Zillikens, Christian D. Sadik, Tanya Sezin, Lisa-Maria Meyne
Publikováno v:
Journal of Dermatological Science. 94:196-204
Background GPR15 has been implicated in the pathogenesis of T cell-driven inflammation of the skin and the gut. Expression levels of the GPR15 ligand GPR15 L are increased in psoriatic skin and considered as potential biomarker for the treatment resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e713b331044a5239ea9a21f58722853c
https://doi.org/10.1016/j.jdermsci.2019.01.008
https://doi.org/10.1016/j.jdermsci.2019.01.008