Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Tanya M. Osicka"'
Autor:
George Jerums, Tanya M. Osicka, Laura Stamp, Angelo D'Amore, Mary Jane Black, Alana Auden, Sianna Panagiotopoulos
Publikováno v:
Cardiovascular Pathology. 19:361-370
Introduction Diabetes in human subjects is often associated with hypertension. The aim of this study was to examine the development of cardiac fibrosis following induction of type 1 diabetes in genetically hypertensive rats. Methods Diabetes was indu
Publikováno v:
Laboratory Medicine. 38:35-38
Microalbuminuria is an important clinical marker in patients with diabetes because of its well-established association with progressive renal disease. It is also becoming increasingly recognized as an independent risk factor for cardiovascular diseas
Publikováno v:
Clinical Biochemistry. 39:143-151
Objectives: To compare the analysis of different forms of intact albumin in urine from healthy volunteers. To determine contamination by common non-albumin proteins on HPLC analysis of urinary albumin and of purified immuno-unreactive albumin. Design
Publikováno v:
Journal of Laboratory and Clinical Medicine. 145:239-246
Large quantities of peptides (1-4 g) are excreted in human urine each day. In this study we sought to analyze how peptide excretion varies with increasing albuminuria associated with diabetes, as well as to characterize the size distribution of album
Autor:
Tanya M. Osicka, Wayne D. Comper
Publikováno v:
Advances in Chronic Kidney Disease. 12:170-176
Microalbuminuria is an important clinical marker in patients with diabetes and cardiovascular disease. The concentration of albumin in urine has traditionally been measured by semiquantitative dipsticks or by various quantitative immunochemical metho
Autor:
Kimberley Strong, Robert C. Atkins, Tanya M. Osicka, George Jerums, Wayne D. Comper, David J. Nikolic-Paterson
Publikováno v:
Monash University
BACKGROUND: Plasma albumin has been considered as important for governing glomerular permselectivity as well as being tubulotoxic in proteinuric states. The purpose of this study was to examine glomerular permselectivity and protein clearance of plas
Autor:
Gail C Brammar, Tanya M. Osicka, Leileata M. Russo, Mei-Lan Qiu, Vicki Thallas, Josephine M. Forbes, George Jerums, Wayne D. Comper
Publikováno v:
Journal of Hypertension. 21:2399-2407
Objective This study examined the separate and combined effects of hypertension and diabetes on renal cortical expression of protein kinase C (PKC) isoforms -beta 1, -beta 2, -alpha and -epsilon, to determine whether albuminuria is the result of an i
Autor:
Mark E. Cooper, Zemin Cao, Tanya M. Osicka, Josephine M. Forbes, Hany Ghabrial, Merlin C. Thomas, Phillip Kantharidis, Wendy C. Burns, Leileata M. Russo, Vicki Thallas, Chris Tikellis, George Jerums
Publikováno v:
Kidney International. 63(6):2152-2161
Reduced tubular cation transport in diabetes: Prevented by ACE inhibition. Background The renal clearance of organic cations is important for the homeostasis of a number of exogenous and endogenous compounds. The organic cation transporters (OCTs) si
Autor:
Riccardo Candido, Leileata M. Russo, Tanya M. Osicka, Wayne D. Comper, George Jerums, Gail C Brammar
Publikováno v:
American Journal of Nephrology. 23:61-70
Background/Aims: Recent studies show that albuminuria may be the result of changes in post-glomerular cellular uptake and processing of albumin. This study aims to determine whether this processing is disrupted in diabetes and/or hypertension. Method
Autor:
Leileata M. Russo, Fabrice Bonnet, Tanya M. Osicka, Robert M. Carey, Riccardo Candido, Zemin Cao, Mark E. Cooper, David J. Casley
Publikováno v:
Journal of Hypertension. 20:1615-1624
The aims of this study were to assess the renal expression of angiotensin type 1 (AT1) and type 2 (AT2) receptors in diabetic spontaneously hypertensive rats (SHR) and the effect of AT1 receptor blockade on the expression of these receptors.Diabetes