Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tanya L. Jensen"'
Autor:
Yaddanapudi Ravindranath, Tanya L. Jensen, Steven Buck, Larry H. Matherly, Ronald Thomas, Jeffrey W. Taub, Mark Stout, Dana Tatman, Yubin Ge
Publikováno v:
JNCI Journal of the National Cancer Institute. 97:226-231
Down syndrome children with acute megakaryocytic leukemia (AMkL) have higher cure rates than non-Down syndrome acute myeloid leukemia (AML) patients treated with cytosine arabinoside (ara-C). Megakaryoblasts from Down syndrome AML patients are more s
Autor:
Robin M. Flatley, Mark Stout, Yubin Ge, Tanya L. Jensen, Patrick J. Grohar, Larry H. Matherly, Yaddanapudi Ravindranath, Jeffrey W. Taub
Publikováno v:
Cancer Research. 64:728-735
Myeloblasts from Down syndrome (DS) children with acute myeloid leukemia (AML) are significantly more sensitive in vitro to 1-β-d-arabinofuranosylcytosine (ara-C) and generate higher 1-β-d-arabinofuranosylcytosine 5′-triphosphate (ara-CTP) than n
Publikováno v:
Journal of Biological Chemistry. 278:49901-49910
Deoxycytidine kinase (EC 2.7.1.74, dCK) is central to drug activity of anticancer and antiviral agents such as cytosine arabinoside (araC) and gemcitabine. HepG2 hepatocellular carcinoma cells were used to study the transcriptional regulation of dCK.
Publikováno v:
Blood. 101:1551-1557
Children with Down syndrome (DS) with acute myeloid leukemia (AML) have significantly higher event-free survival rates compared to those with non-DS AML, linked to greater cytosine arabinoside (ara-C) sensitivity and higher transcript levels of the c
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1579:73-80
Cystathionine-β-synthase (CBS) catalyzes the condensation of serine and homocysteine to form cystathionine, an intermediate step in the synthesis of cysteine. We previously described essential transactivating roles for specificity protein 1 (Sp1), S
Autor:
Larry H. Matherly, Tanya L. Jensen, Jeffrey W. Taub, Yaddanapudi Ravindranath, Yubin Ge, Steven Buck, Dana Tatman, Mark Stout
Publikováno v:
Leukemia. 19:677-679
Role of USF1 in the differential expression of the human deoxycytidine kinase gene in acute myeloid leukemia
Autor:
Yaddanapudi Ravindranath, G V Massey, Yubin Ge, Larry H. Matherly, Tanya L. Jensen, S J James, D L Becton, Howard J. Weinstein, Jeffrey W. Taub
Publikováno v:
Leukemia. 16:2339-2341
High frequency of the 844ins68 cystathionine-β-synthase gene variant in Down syndrome children with acute myeloid leukemia
Autor:
Janet Poulik, Larry H. Matherly, Yubin Ge, S. Jill James, Faisal Qureshi, John D. Crispino, Gina Mundschau, Tanya L. Jensen, Jeffrey W. Taub, Joshua B. Wechsler
Publikováno v:
Blood. 104:1588-1589
Recently, somatic mutations in exon 2 of the transcription factor GATA1 gene have been detected in essentially all Down syndrome (DS) megakaryocytic leukemia (AMkL) and transient myeloproliferative disorder (TMD) cases.[1][1] This is the most specifi