Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tanya Jayne"'
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-5 (2021)
Abstract Objective NGFR/p75NTR and NRADD/NRH proteins are closely related structurally and are encoded by genes that arose from a duplication event early in vertebrate evolution. The transmembrane domain (TMD) of NGFR is cleaved by γ-secretase but t
Externí odkaz:
https://doaj.org/article/ac89740387da41a380f6ce0fb9f9d4a3
γ-secretase is an important protease complex responsible for the cleavage of over 100 substrates within their transmembrane domains. γ-secretase acts in Alzheimer’s disease by cleavage of AMYLOID BETA (A4) PRECURSOR PROTEIN to produce aggregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12554aa37eebab256972d615270cbc6b
Autor:
Giuseppe Verdile, Michael Lardelli, Greg T. Sutherland, Tanya Jayne, Ian F. Musgrave, Morgan Newman, Gerald Münch, Seyyed Hani Moussavi Nik
Publikováno v:
Journal of Alzheimer's Disease. 52:781-799
The majority of mutations causing familial Alzheimer's disease (fAD) have been found in the gene PRESENILIN1 (PSEN1) with additional mutations in the related gene PRESENILIN2 (PSEN2). The best characterized function of PRESENILIN (PSEN) proteins is i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdf38375bb2e5b38a979f4bc7ebc27b
https://doi.org/10.3233/jad-151186
https://doi.org/10.3233/jad-151186
The HIGH MOBILITY GROUP AT-HOOK 1 (HMGA1) family of chromatin-binding proteins plays important roles in cellular responses to low oxygen. HMGA1 proteins regulate gene activity both in the nucleus and within mitochondria. They are expressed mainly dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2401de7c1555373874b0669e35e2c0
https://doi.org/10.1101/241927
https://doi.org/10.1101/241927
Autor:
Bodenham, Tanya Jayne
Peritoneal fibrosis is a significant problem for peritoneal dialysis patients resulting in a loss in membrane dialysing capacity ultimately leading to technique failure. The development of peritoneal fibrosis is attributed to recurrent peritonitis in
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.669161
Autor:
Marchant, Tanya Jayne
Anaemia in pregnancy is one of the main maternal health problems globally, affecting over 50% of pregnant women in sub-Saharan Africa. Although not always shown to have a causal link, severe anaemia contributes to maternal morbidity and mortality and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c8175eb8347db77d6a7a384f2edc2a
https://edoc.unibas.ch/39/
https://edoc.unibas.ch/39/