Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tanya Heare"'
Autor:
Frances M. Platt, Tanya Heare, Raymond A. Dwek, Mylvaganam Jeyakumar, Terry D. Butters, Ulrika Andersson
Substrate reduction therapy uses small molecules to slow the rate of glycolipid biosynthesis. One of these drugs, N –butyldeoxynojirimycin (NB–DNJ), shows efficacy in mouse models of Tay–Sachs, Sandhoff and Fabry diseases. This offers the prosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ed73b6db0a52e1a05902a6204cdb78
https://ora.ox.ac.uk/objects/uuid:3539421f-78bb-40c4-a382-aa86b04104a2
https://ora.ox.ac.uk/objects/uuid:3539421f-78bb-40c4-a382-aa86b04104a2
Autor:
Terry D. Butters, Tanya Heare, Frances M. Platt, Vincenzo Cerundolo, François Trottein, Nick Platt, Mariolina Salio, Anneliese O. Speak, Josette Fontaine, Raymond A. Dwek, Mark A. Exley, David A. Priestman, David C. A. Neville
Development of invariant natural killer T (iNKT) cells requires the presentation of lipid ligand(s) by CD1d molecules in the thymus. The glycosphingolipid (GSL) isoglobotrihexosylceramide (iGb3) has been proposed as the natural iNKT cell-selecting li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f2fa8207b74c561e260cd31d3dd897
https://doi.org/10.1073/pnas.0607285104
https://doi.org/10.1073/pnas.0607285104
Autor:
Frances M. Platt, Kieran Clarke, A B Kulkarni, Tanya Heare, David A. Priestman, Keith M. Channon, Nicholas J. Alp, Raymond A. Dwek, T D Butters, P Qasba
Publikováno v:
Europe PubMed Central
OBJECTIVE: Fabry disease results from alpha-gala-ctosidase A deficiency and is characterized by the lysosomal accumulation of globotriaosylceramide. Globotriaosylceramide storage predominantly affects endothelial cells, altering vascular wall morphol
Autor:
Frances M. Platt, Mylvaganam Jeyakumar, Ulrika Andersson, Tanya Heare, Raymond A. Dwek, Terry D. Butters
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences; May2003, Vol. 358 Issue 1433, p947-954, 8p