Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tanya Ditschun"'
Autor:
Lan Zhang, Hanghui Liu, Brett Weylan Ching, Guy Servant, Tanya Ditschun, Andrew Patron, Thomas Brady, Mark C. Williams, Melissa Arellano, Vincent Darmohusodo, Michael Saganich, Qing Chen, Timothy Davis, Catherine Tachdjian, Donald S. Karanewsky, Joseph R. Fotsing
Publikováno v:
Journal of medicinal chemistry. 63(9)
In humans, bitter taste is mediated by 25 TAS2Rs. Many compounds, including certain active pharmaceutical ingredients, excipients, and nutraceuticals, impart their bitter taste (or in part) through TAS2R8 activation. However, effective TAS2R8 blocker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bf37e3c7509316160de3e35812932e
https://pubmed.ncbi.nlm.nih.gov/32330040
https://pubmed.ncbi.nlm.nih.gov/32330040
Autor:
Faber Nathan, Alain Noncovich, Guy Servant, Nicole Gonsalves, Paul Brust, Tanya Ditschun, Jane Ung, Andrew Patron, Hanghui Liu, Nicole Servant, Chad Priest
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:3931-3938
The paper presents the activity trends for a novel series of phenoxyacetyl amides as human TRPM8 receptor agonists. This series encompasses in vitro activity values ranging from the micromolar to the picomolar levels. Sensory evaluation of these mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b055d78c3adc8356a22f49b490adfa
https://doi.org/10.1016/j.bmcl.2017.04.003
https://doi.org/10.1016/j.bmcl.2017.04.003
Autor:
Goran Petrovic, Feng Zhang, Xiao-Qing Tang, Catherine Tachdjian, Grant E. Dubois, Tanya Ditschun, Sara Werner, Mark Zoller, Poonit Kamdar, Paul Brust, Donald S. Karanewsky, Guy Servant, Antoniette Java, Xiaodong Li, Nicole Brune
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(10)
To identify molecules that could enhance sweetness perception, we undertook the screening of a compound library using a cell-based assay for the human sweet taste receptor and a panel of selected sweeteners. In one of these screens we found a hit, SE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d2ae7fdd116ea297cfa5ef6aa93369
https://pubmed.ncbi.nlm.nih.gov/20173092
https://pubmed.ncbi.nlm.nih.gov/20173092