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Synthesis, characterization of some pyrazine derivatives as anti-cancer agents: In vitro and in Silico approaches

Autor: Tantawy, Eman S., Amer, Atef M., Mohamed, Enaiat K., Abd Alla, Mohamed M., Nafie, Mohamed S.

Publikováno v: In Journal of Molecular Structure 15 June 2020 1210

Synthesis of novel bioactive pyrido[2,3-d]pyrimidine derivatives with potent cytotoxicity through apoptosis as PIM-1 kinase inhibitors.

Autor: Tantawy, Eman S., Nafie, Mohamed S., Morsy, Hesham A., El-Sayed, Hassan A., Moustafa, Ahmed H., Mohammed, Samar M.

Publikováno v: RSC Advances; 2024, Vol. 14 Issue 16, p11098-11111, 14p

Synthesis of novel bioactive pyrido[2,3- d ]pyrimidine derivatives with potent cytotoxicity through apoptosis as PIM-1 kinase inhibitors.

Autor: Tantawy ES; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt., Nafie MS; Department of Chemistry, College of Sciences, University of Sharjah P. O. 27272 Sharjah United Arab Emirates mohamed.elsayed@sharjah.ac.ae.; Chemistry Department, Faculty of Science, Suez Canal University P. O. 41522 Ismailia Egypt mohamed_nafie@science.suez.edu.eg., Morsy HA; Higher Institution of Engineering & Modern Technology Elmarg Cairo 13774 Egypt., El-Sayed HA; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt., Moustafa AH; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt., Mohammed SM; Department of Chemistry, Faculty of Science, Zagazig University Zagazig 44519 Egypt.

Publikováno v: RSC advances [RSC Adv] 2024 Apr 05; Vol. 14 (16), pp. 11098-11111. Date of Electronic Publication: 2024 Apr 05 (Print Publication: 2024).