Whole exome sequencing and rare variant association study to identify genetic modifiers, KLF1 mutations, and a novel double mutation in Thai patients with hemoglobin E/beta-thalassemia.

Autor: Hantaweepant C; Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Suktitipat B; Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.; Integrative Computational BioScience (ICBS) Center, Mahidol University, Nakhon Pathom, Thailand., Pithukpakorn M; Division of Medical Genetics, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.; Siriraj Genomics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Chinthammitr Y; Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Limwongse C; Division of Medical Genetics, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Tansiri N; Division of Hematology, Department of Medicine, Uttaradit Hospital, Uttaradit, Thailand., Sawatnatee S; Division of Hematology, Department of Medicine, Sunpasitthiprasong Hospital, Ubon Ratchathani, Thailand., Takpradit C; Division of Hematology-Oncology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Rotchanapanya W; Division of Hematology, Department of Medicine, Chiangrai Prachanukroh Hospital, Chiangrai, Thailand., Pongudom S; Division of Hematology, Department of Medicine, Udonthani Hospital, Udonthani, Thailand., Charoenprasert K; Division of Hematology, Department of Medicine, Sisaket Hospital, Sisaket, Thailand., Paiboonsukwong K; Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand., Thamprasert W; Division of Hematology, Department of Medicine, Nakhon Pathom Hospital, Nakhon Pathom, Thailand., Nolwachai N; Division of Hematology, Department of Medicine, Saraburi Hospital, Saraburi, Thailand., Rattanasawat W; Division of Hematology, Department of Medicine, Charoenkrung Pracharak Hospital, Bangkok, Thailand., Sae-Aeng B; Division of Hematology, Department of Medicine, Banphaeo General Hospital, Samutsakhon, Thailand., Khorwanichakij N; Division of Hematology, Department of Medicine, Chaophra Yommarat Hospital, Suphanburi, Thailand., Saetow P; Division of Hematology, Department of Medicine, Faculty of Medicine, Lerdsin Hospital, Bangkok, Thailand., Saengboon S; Division of Hematology, Department of Medicine, Faculty of Medicine, Thammasat University Hospital, Pathumthani, Thailand., Kamjornpreecha K; Division of Hematology, Department of Medicine, Police General Hospital, Bangkok, Thailand., Pholmoo W; Division of Hematology, Department of Medicine, Pathumthani Hospital, Pathumthani, Thailand., Dujjawan B; Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Siritanaratkul N; Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Publikováno v: Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2187155.

Transcription Factors in Blood Cell Development

Autor: Tilman Borggrefe, Benedetto Daniele Giaimo

This book describes transcription factors in the context of hematopoietic development and reveal mechanistic insights how they orchestrate specific gene expression patterns. Several examples from lymphoid and myeloid lineages are given as well as par