Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tanos C.C. França"'
Publikováno v:
Results in Chemistry, Vol 6, Iss , Pp 101094- (2023)
Phenazines derived from β-lapachone had tuberculostatic activity reported in the literature. However, very little is known about their mechanism of action or molecular targets. In order to investigate this, we performed an in silico study through mo
Externí odkaz:
https://doaj.org/article/d091a5c286534eafa966a630e512da5d
Autor:
Marcelo C. Santos, Fernanda D. Botelho, Arlan S. Gonçalves, Kamil Kuca, Eugenie Nepovimova, Samir F.A. Cavalcante, Antonio L.S. Lima, Tanos C.C. França
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 165
The nerve agents of the A-series are relatively recent chemical weapons with no antidote available yet. Once inside the human body, those chemicals act similarly to the classic nerve agents, by binding to the catalytic residue Serine 203 (Ser203) of
Organophosphorus compounds (OP) are mainly used in agriculture as pesticides. Unfortunately, each year many rural workers die intoxicated by those compounds. Sometimes the diagnosis of the exact molecule that caused the intoxication can be tardy. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1235d3aca2c850f35b7ea0c9e10930ec
https://doi.org/10.26434/chemrxiv.9037532.v1
https://doi.org/10.26434/chemrxiv.9037532.v1
Autor:
Zofia Chrienova, David Rysanek, Josef Novak, Pavla Vasicova, Patrik Oleksak, Rudolf Andrys, Adam Skarka, Jelena Dumanovic, Zoran Milovanovic, Vesna Jacevic, Marketa Chvojkova, Kristina Holubova, Karel Vales, Veronika Skoupilova, Marian Valko, Klaudia Jomova, Suliman Y. Alomar, Fernanda D. Botelho, Tanos C.C. Franca, Kamil Kuca, Zdenek Hodny, Eugenie Nepovimova
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115600- (2023)
Frentizole is immunosuppressive drug with low acute toxicity and lifespan-prolonging effect. Recently, frentizole´s potential to disrupt toxic amyloid β (Aβ) - Aβ-binding alcohol dehydrogenase (ABAD) interaction in mitochondria in Alzheimer´s br
Externí odkaz:
https://doaj.org/article/44e7104b724844208bfcb788fd0917db