Multiparametric MRI to quantify disease and treatment response in mice with myeloproliferative neoplasms

Autor: Tanner H. Robison, Manisha Solipuram, Kevin Heist, Ghoncheh Amouzandeh, Winston Y. Lee, Brock A. Humphries, Johanna M. Buschhaus, Avinash Bevoor, Anne Zhang, Kathryn E. Luker, Kristen Pettit, Moshe Talpaz, Dariya Malyarenko, Thomas L. Chenevert, Brian D. Ross, Gary D. Luker

Publikováno v: JCI Insight, Vol 7, Iss 19 (2022)

Histopathology, the standard method to assess BM in hematologic malignancies such as myeloproliferative neoplasms (MPNs), suffers from notable limitations in both research and clinical settings. BM biopsies in patients fail to detect disease heteroge

Externí odkaz: https://doaj.org/article/1994fad9d3384177bca710b47a9b5c64

Bone Marrow Mesenchymal Stem Cells Induce Metabolic Plasticity in Estrogen Receptor–Positive Breast Cancer

Autor: Johanna M. Buschhaus, Shrila Rajendran, Siyi Chen, Bryan L. Wharram, Avinash S. Bevoor, Alyssa C. Cutter, Brock A. Humphries, Tanner H. Robison, Alex P. Farfel, Gary D. Luker

Publikováno v: Molecular Cancer Research. 21:458-471

Cancer cells reprogram energy metabolism through metabolic plasticity, adapting ATP-generating pathways in response to treatment or microenvironmental changes. Such adaptations enable cancer cells to resist standard therapy. We employed a coculture m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de9b54daf329e2c842e39147531ab456
https://doi.org/10.1158/1541-7786.mcr-22-0451

Supplementary Table 1 from Bone Marrow Mesenchymal Stem Cells Induce Metabolic Plasticity in Estrogen Receptor–Positive Breast Cancer

Autor: Gary D. Luker, Alex P. Farfel, Tanner H. Robison, Brock A. Humphries, Alyssa C. Cutter, Avinash S. Bevoor, Bryan L. Wharram, Siyi Chen, Shrila Rajendran, Johanna M. Buschhaus

1. Quantified metabolic shifts in response to antiestrogenic therapy and MCT1/4 inhibition. Change in median values in picoseconds of NADH or CFP lifetime (ATP) after addition of each compound. Labels at the top of the table denote the relevant compa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac915a1d428f81eefe1189e30a52394f
https://doi.org/10.1158/1541-7786.22725374.v1

Quantitative MRI Identifies Heterogeneous Bone Marrow Treatment Responses in a Mouse Model of Myelofibrosis

Autor: Tanner H Robison, Manisha Solipuram, Winston Y Lee, Kathryn Luker, Kristen M. Pettit, Moshe Talpaz, Dariya Malyarenko, Thomas Chenevert, Brian Ross, Gary Luker

Publikováno v: Blood. 140:3860-3861

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da13cce24efab77361bdd6600aad334c
https://doi.org/10.1182/blood-2022-166797

Anthoceros genomes illuminate the origin of land plants and the unique biology of hornworts

Autor: Isabel Monte, Pierre-Marc Delaux, Zheng Li, Dolf Weijers, Noe Fernandez-Pozo, Jan de Vries, Alexander Kirbis, Shifeng Cheng, Tanner A. Robison, Keiko Sakakibara, Jill C. Harrison, Sumanth K. Mutte, Péter Szövényi, Stefan A. Rensing, Tomoaki Nishiyama, Sophie de Vries, Masaki Shimamura, Tom Bennett, Miguel A. Blázquez, Eftychios Frangedakis, Jorge Hernández-García, Manuel Waller, Duncan A. Hauser, Juan Carlos Villarreal, John C. Meeks, Gane Ka-Shu Wong, Jean Keller, Dietmar Quandt, Michael S. Barker, Fay-Wei Li, Susann Wicke, Andrew C. Cuming, Issa S. Diop, Anna Neubauer

Publikováno v: Nature Plants
Nature plants, vol 6, iss 3
Nature Plants, 6(3), 259-272
Nature Plants, Nature Publishing Group, 2020, 6 (3), pp.259-272. ⟨10.1038/s41477-020-0618-2⟩
Nature Plants 6 (2020) 3
Digital.CSIC. Repositorio Institucional del CSIC
instname
Li, F-W, Nishiyama, T, Waller, M, Frangedakis, E, Keller, J, Li, Z, Fernandez-Pozo, N, Barker, M S, Bennett, T A, Blazquez, M A, Cheng, S, Cuming, A, de Vries, J, de Vries, S, Delaux, P-M, Diop, I S, Harrison, C J, Hauser, D, Hernandez-Garcia, J, Kirbis, A, Meeks, J, Monte, I, Mutte, S K, Neubauer, A, Quandt, D, Robison, T, Shimamura, M, Rensing, S, Villareal, J C, Weijers, D, Wicke, S, Wong, G K-S, Sakakibara, K & Szövényi, P 2020, ' Anthoceros genomes illuminate the origin of land plants and the unique biology of hornworts ', Nature Plants, vol. 6, pp. 259–272 . https://doi.org/10.1038/s41477-020-0618-2

Hornworts comprise a bryophyte lineage that diverged from other extant land plants >400 million years ago and bears unique biological features, including a distinct sporophyte architecture, cyanobacterial symbiosis and a pyrenoid-based carbon-concent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212fd3788724b911a318d9679ba5f2bf
https://eprints.whiterose.ac.uk/158969/1/s41477-020-0618-2.pdf