Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tannenbaum, Steven Robert"'
Autor:
Sarkar, Ujjal, Rivera-Burgos, Dinelia, Large, Emma M., Hughes, David J., Kodihalli, Ravindra, Dyer, Rachel Lee, Ebrahimkhani, Mohammad Reza, Wishnok, John S., Griffith, Linda G., Tannenbaum, Steven Robert
Publikováno v:
Tannenbaum
Endotoxin lipopolysaccharide (LPS) is known to cause liver injury primarily involving inflammatory cells such as Kupffer cells, but few in vitro culture models are applicable for investigation of inflammatory effects on drug metabolism. We have devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od________88::f32614be6444793e92e030e328c8958a
https://orcid.org/0000-0002-2325-552X
https://orcid.org/0000-0002-2325-552X
Autor:
Slade, Peter G., Williams, Michelle V., Brahmbhatt, Viral, Wishnok, John S., Dash, Ajit, Tannenbaum, Steven Robert
Publikováno v:
PubMed Central
The hydroperoxide of linoleic acid (13-HPODE) degrades to 9,12-dioxo-10(E)-dodecenoic acid (DODE), which readily modifies proteins. This study identified the major proteins in MCF7 cells modified by DODE. To reduce false positives, three methods were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3b65a1f435cf69a07ce62b58a4445c
https://orcid.org/0000-0002-2325-552X
https://orcid.org/0000-0002-2325-552X
Publikováno v:
PMC
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disorder of the bowel. The etiology remains unknown, but IBD is immune-driven and multiple factors including genetic, environmental, and microbiological components play a role. Reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae1bf4f0fd38562a39ecf939d00d5d1
https://doi.org/10.1021/pr300429x
https://doi.org/10.1021/pr300429x
Publikováno v:
Carcinogenesis
PubMed Central
PubMed Central
Alkylanilines are a group of chemicals whose ubiquitous presence in the environment is a result of the multitude of sources from which they originate. Exposure assessments indicate that most individuals experience lifelong exposure to these compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa2a7f411d75a69ff52ef8aca7e4cba
https://doi.org/10.1093/carcin/bgp267
https://doi.org/10.1093/carcin/bgp267
Publikováno v:
Prof. Dedon via Howard Sliver
The intestine comprises an exceptional venue for a dynamic and complex interplay of numerous chemical and biological processes. Here, multiple chemical and biological systems, including the intestinal tissue itself, its associated immune system, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd1edfaaf988a2eed8a955ae092ec53
https://pubmed.ncbi.nlm.nih.gov/23926919
https://pubmed.ncbi.nlm.nih.gov/23926919
Autor:
Paul L. Skipper, Craig W. Hendrix, Rosa G. Liberman, Charles Flexner, Nicolette A. Louissaint, Steven R. Tannenbaum, Jianmeng Chen, Edward J. Fuchs
Publikováno v:
PMC
Objective: Phase 0 studies can provide initial pharmacokinetics (PKs) data in humans and help to facilitate early drug development, but their predictive value for standard dosing is controversial. To evaluate the prediction of microdosing for active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf090a584a64a232506fe8dc386d569
https://pubmed.ncbi.nlm.nih.gov/23187888
https://pubmed.ncbi.nlm.nih.gov/23187888
Autor:
Steven R. Tannenbaum, Zheng Bo, Eng Eong Ooi, Cui Liang, Yadunanda Kumar, Jagath C. Rajapakse
Publikováno v:
PLoS Neglected Tropical Diseases
PLos
PLoS Neglected Tropical Diseases, Vol 6, Iss 11, p e1887 (2012)
PLos
PLoS Neglected Tropical Diseases, Vol 6, Iss 11, p e1887 (2012)
Background Infections caused by dengue virus are a major cause of morbidity and mortality in tropical and subtropical regions of the world. Factors that control transition from mild forms of disease such as dengue fever (DF) to more life-threatening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ec5e31661b4a18a10adda3a3508419
http://europepmc.org/articles/PMC3510095
http://europepmc.org/articles/PMC3510095
Publikováno v:
PMC
Oncotarget
Oncotarget
The importance of chronic inflammation as a risk factor for major cancers is well documented [1], and the inflammatory state is known to involve contributions of both adaptive and innate immune components. In a recent publication [2] we describe an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c770ae5543bc02a97c8979a27731868
https://orcid.org/0000-0003-0011-3067
https://orcid.org/0000-0003-0011-3067
Autor:
James G. Fox, Sureshkumar Muthupalani, David B. Schauer, Arkadiusz R. Raczynski, Katherine Ann Schlieper, Steven R. Tannenbaum
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 3, p e33099 (2012)
PLoS
PLoS ONE, Vol 7, Iss 3, p e33099 (2012)
PLoS
Acute and chronic forms of inflammation are known to affect liver responses and susceptibility to disease and injury. Furthermore, intestinal microbiota has been shown critical in mediating inflammatory host responses in various animal models. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9b900b75daec14d168b4dbfc3a8386
http://europepmc.org/articles/PMC3302869
http://europepmc.org/articles/PMC3302869
Autor:
Elizabeth M. Iffrig, Peter G. Slade, Alison Chiang, Steven R. Tannenbaum, John S. Wishnok, Michelle V. Williams
Publikováno v:
Prof. Tannenbaum via Howard Silver
During inflammation, the resulting oxidative stress can damage surrounding host tissue, forming protein-carbonyls. The SJL mouse is an experimental animal model used to assess in vivo toxicological responses to reactive oxygen and nitrogen species fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c04f95a36d89fd30155f46f276bbbe7
https://orcid.org/0000-0002-2325-552X
https://orcid.org/0000-0002-2325-552X