Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Tanmay S Chavan"'
Autor:
Tanmay S Chavan, Ricky C Cheng, Tao Jiang, Irimpan I Mathews, Richard A Stein, Antoine Koehl, Hassane S Mchaourab, Emad Tajkhorshid, Merritt Maduke
Publikováno v:
eLife, Vol 9 (2020)
Among coupled exchangers, CLCs uniquely catalyze the exchange of oppositely charged ions (Cl– for H+). Transport-cycle models to describe and explain this unusual mechanism have been proposed based on known CLC structures. While the proposed models
Externí odkaz:
https://doaj.org/article/b749e602edbc4f7ab3d6e58d1b99d2b3
Publikováno v:
Molecules, Vol 18, Iss 6, Pp 7103-7119 (2013)
NMR is commonly used to investigate macromolecular interactions. However, sensitivity problems hamper its use for studying such interactions at low physiologically relevant concentrations. At high concentrations, proteins or peptides tend to aggregat
Externí odkaz:
https://doaj.org/article/9acfe215a1ee47189d72bbc840640ac6
Autor:
Chandra M Khantwal, Sherwin J Abraham, Wei Han, Tao Jiang, Tanmay S Chavan, Ricky C Cheng, Shelley M Elvington, Corey W Liu, Irimpan I Mathews, Richard A Stein, Hassane S Mchaourab, Emad Tajkhorshid, Merritt Maduke
Publikováno v:
eLife, Vol 5 (2016)
CLC secondary active transporters exchange Cl- for H+. Crystal structures have suggested that the conformational change from occluded to outward-facing states is unusually simple, involving only the rotation of a conserved glutamate (Gluex) upon its
Externí odkaz:
https://doaj.org/article/412dc066a96c480c9b531c04b7b4fecb
Autor:
Richard A. Stein, Irimpan I. Mathews, Emad Tajkhorshid, Ricky C. Cheng, Merritt Maduke, Tanmay S. Chavan, Tao Jiang, Antoine Koehl, Hassane S. Mchaourab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6967c753ba0c285cab5eb80d0a803d48
https://doi.org/10.7554/elife.53479.sa2
https://doi.org/10.7554/elife.53479.sa2
Autor:
Richard A. Stein, Irimpan I. Mathews, Ricky C. Cheng, Merritt Maduke, Hassane S. Mchaourab, Emad Tajkhorshid, Tanmay S. Chavan, Tao Jiang, Antoine Koehl
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Among coupled exchangers, CLCs uniquely catalyze the exchange of oppositely charged ions (Cl– for H+). Transport-cycle models to describe and explain this unusual mechanism have been proposed based on known CLC structures. While the proposed models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483628272debb9b2c034cab67c9dc317
http://europepmc.org/articles/PMC7253180
http://europepmc.org/articles/PMC7253180
Publikováno v:
Journal of Biological Chemistry. 292:12544-12559
In calmodulin (CaM)-rich environments, oncogenic KRAS plays a critical role in adenocarcinomas by promoting PI3K/Akt signaling. We previously proposed that at elevated calcium levels in cancer, CaM recruits PI3Kα to the membrane and extracts K-Ras4B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8e2a247d23e4b466da3602c089e63a
https://doi.org/10.1074/jbc.m117.785063
https://doi.org/10.1074/jbc.m117.785063
Publikováno v:
The Journal of General Physiology
Protein toxins from venomous organisms have provided remarkable insights into the structure and mechanism of ion channel proteins ([Kalia et al., 2015][1]). One classic example is the work of Rod MacKinnon, Chris Miller, and their colleagues on the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460f8e47fde6faa5c38990f72b5dff39
http://europepmc.org/articles/PMC5379924
http://europepmc.org/articles/PMC5379924
Autor:
Emad Tajkhorshid, Richard A. Stein, Ricky C. Cheng, Hassane S. Mchaourab, Irimpan I. Mathews, Merritt Maduke, Tanmay S. Chavan, Tao Jiang, Antoine Koehl
Among coupled exchangers, CLCs uniquely catalyze the exchange of oppositely charged ions (Cl− for H+). Transport-cycle models to describe and explain this unusual mechanism have been proposed based on known CLC structures. While the proposed models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94322985986b4dd04161ce89a2230919
https://doi.org/10.1101/857136
https://doi.org/10.1101/857136
Autor:
Hyunbum Jang, Avik Banerjee, Tanmay S. Chavan, Liv Johannessen, Sergey G. Tarasov, Sherwin J. Abraham, Ruth Nussinov, Nadya I. Tarasova, Vadim Gaponenko, Benjamin C. Freed, Lyuba Khavrutskii
Publikováno v:
Biophysical Journal. 109(12):2602-2613
Ras proteins are small GTPases that act as signal transducers between cell surface receptors and several intracellular signaling cascades. They contain highly homologous catalytic domains and flexible C-terminal hypervariable regions (HVRs) that diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b5fde79328bdf090c1520bcd15ba50
Autor:
Tanmay S. Chavan, Vladimir Berka, Ayush Krishnamoorti, Richard A. Stein, Irimpan I. Mathews, Merritt Maduke, Vasanthi Jayaraman, Emad Tajkhorshid, Ricky C. Cheng, Tao Jiang, Antoine Koehl, Hassane S. Mchaourab, Ryan J. Durham
Publikováno v:
Biophysical Journal. 118:443a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52a369e7ee999bc0661463175a1e81e8
https://doi.org/10.1016/j.bpj.2019.11.2481
https://doi.org/10.1016/j.bpj.2019.11.2481