Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tanlin Sun"'
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background The liquid–liquid phase separation (LLPS) of biomolecules in cell underpins the formation of membraneless organelles, which are the condensates of protein, nucleic acid, or both, and play critical roles in cellular function. Dys
Externí odkaz:
https://doaj.org/article/7a49c01f01d548a1bf5e59bdf37cc83d
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Background Protein-protein interactions (PPIs) are critical for many biological processes. It is therefore important to develop accurate high-throughput methods for identifying PPI to better understand protein function, disease occurrence, a
Externí odkaz:
https://doaj.org/article/293de1787b034876bd0de98d6c131b1c
Publikováno v:
Quantitative Biology. 6:334-343
Computational tools have been widely used in drug discovery process since they reduce the time and cost. Prediction of whether a protein is druggable is fundamental and crucial for drug research pipeline. Sequence based protein function prediction pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b8c4344207455c6ad3c0df24c049c0c
https://doi.org/10.1007/s40484-018-0157-2
https://doi.org/10.1007/s40484-018-0157-2
The liquid-liquid phase separation (LLPS) of biomolecules in cell underpins the formation of membraneless organelles, which are the condensates of protein, nucleic acid, or both, and play critical roles in cellular function. Dysregulation of LLPS is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea4f8035881966f07eef368d3be2071
https://doi.org/10.1101/842336
https://doi.org/10.1101/842336
Publikováno v:
Molecular BioSystems. 12:2932-2940
To extract protein dimension and energetics information from single-molecule fluorescence resonance energy transfer spectroscopy (smFRET) data, it is essential to establish the relationship between the distributions of the radius of gyration (Rg) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db3e76a9f5a691fb6f803868feab0c0
https://doi.org/10.1039/c6mb00415f
https://doi.org/10.1039/c6mb00415f
Autor:
JianFeng Pei, TanLin Sun
Publikováno v:
Chinese Science Bulletin. 60:689-693
Big data brings new ways of data-driven drug research and development, which are expected to prominently increase the success rate, shorten the time and reduce the cost of drug discovery. In this review, we briefly summarized the development of data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::682b68737d5042180c7ba647587aae32
https://doi.org/10.1360/n972014-01114
https://doi.org/10.1360/n972014-01114
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-8 (2017)
BMC Bioinformatics
BMC Bioinformatics
Background Protein-protein interactions (PPIs) are critical for many biological processes. It is therefore important to develop accurate high-throughput methods for identifying PPI to better understand protein function, disease occurrence, and therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e623236fb51c19591c69b5c2f3c3f0
https://doi.org/10.1186/s12859-017-1700-2
https://doi.org/10.1186/s12859-017-1700-2
Detailed information for the benchmark and the external test sets. Table S1. Detailed information for the benchmark and the external test sets. (DOCX 14 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef87b6cc5eee08ee7ec9ab9c41919c9
Detailed information about the training model. (DOCX 15 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25da073036b07268884b6b2f516ac908
More details about the redundancy removal of the test set. (DOCX 14 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a56243b297b91dc0f0255b709cc5f96