Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tanjore K. Narayanan"'
Publikováno v:
Journal of Nuclear Medicine. 53:1709-1715
The aim of this study was to compare the grading and prognostic value of l-[methyl-(11)C]-methionine ((11)C-MET) PET in glioma patients with (18)F-FDG PET and contrast-enhanced MRI.Patients (n = 102) with histopathologically confirmed gliomas were fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9665b850b2692cf0e51345f36da351
https://doi.org/10.2967/jnumed.111.102533
https://doi.org/10.2967/jnumed.111.102533
Autor:
Tanjore K. Narayanan, Bingzhi Shi, Daphne Collins, Balu Easwaramoorthy, Bradley T. Christian, Jogeshwar Mukherjee, Rama Pichika
Publikováno v:
Nuclear Medicine and Biology. 38:1183-1192
Thalamic and extrathalamic nicotinic α4β2 receptors found in the brain have been implicated in Alzheimer's disease, Parkinson's disease, substance abuse and other disorders. We report here the development of 3-(2-( S )-azetidinylmethoxy)-5-(3′-fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f818169aa01ea50ffc5e859c03ed3f9
https://doi.org/10.1016/j.nucmedbio.2011.05.005
https://doi.org/10.1016/j.nucmedbio.2011.05.005
Autor:
Bingzhi Shi, Eileen Kemether, Tanjore K. Narayanan, Monte S. Buchsbaum, Terrence R. Oakes, Douglas S. Lehrer, Bradley T. Christian, Joseph Mantil, Jogeshwar Mukherjee
Publikováno v:
Schizophrenia Research. 85:232-244
Background Abnormalities in the dopaminergic system are implicated in schizophrenia. [F-18]fallypride is a highly selective, high affinity PET ligand well suited for measuring D2/D3 receptor availability in the extrastriatal regions of the brain incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd3349ee25bda66142fbf175093ee21
https://doi.org/10.1016/j.schres.2006.03.042
https://doi.org/10.1016/j.schres.2006.03.042
Autor:
Monte S. Buchsbaum, Tanjore K. Narayanan, Douglas S. Lehrer, Bingzhi Shi, Pamela Strohmeyer, Joseph Mantil, Bradley T. Christian
Publikováno v:
NeuroImage. 31:139-152
We used the highly selective D2/D3 dopamine PET radioligand [F-18]fallypride to demonstrate that cognitive task induced dopamine release can be measured in the extrastriatal region of the thalamus, a region containing 10-fold fewer D2 dopamine recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cd98151205e100f0f6cefd551f44b6
https://doi.org/10.1016/j.neuroimage.2005.11.052
https://doi.org/10.1016/j.neuroimage.2005.11.052
Autor:
Tanjore K. Narayanan, Steven G. Potkin, Bradley T. Christian, Rama Pichika, Jogeshwar Mukherjee, Balasubramaniam Easwaramoorthy, Bingzhi Shi, Daphne Collins
Publikováno v:
Nuclear Medicine and Biology. 33:295-304
The α4β2 nicotinic acetylcholine receptor (nAChR) has been implicated in various neurodegenerative diseases. Optimal positron emission tomography (PET) imaging agents are therefore highly desired for this receptor. We report here the development an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::870a3793cdd9b9ac91e49749b92affd9
https://doi.org/10.1016/j.nucmedbio.2005.12.017
https://doi.org/10.1016/j.nucmedbio.2005.12.017
Publikováno v:
Synapse. 54:83-91
We have evaluated the in vitro autoradiographic binding characteristics and in vivo brain distribution of two high-affinity dopamine D2/D3 receptor agonists, (+/-)-2-(N-phenethyl-N-1'-11C-propyl)amino-5-hydroxytetralin (11C-PPHT) and (+/-)-2-(N-cyclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47e7989f847f8f0784c0dc460979d6e
https://doi.org/10.1002/syn.20068
https://doi.org/10.1002/syn.20068
Autor:
Sankha Chattopadhyay, Bradley T. Christian, Bingzhi Shi, Tanjore K. Narayanan, Jogeshwar Mukherjee
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:95-102
Fallypride [benzamide, 5-(3-fluoropropyl)-2,3-dimethoxy-N-[(2S)-1-(2-propenyl)-2-pyrrolidinyl]methyl]-, CAS RN 166173-78-0] is a selective dopamine D2/D3 receptor antagonist. Carbon-11 labeled fallypride may serve as a radiotracer for use in biomedic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d11934e890860ce6a91e4fa786a71f
https://doi.org/10.1016/j.bmc.2003.10.020
https://doi.org/10.1016/j.bmc.2003.10.020
Autor:
Bradley T. Christian, Joseph Mantil, Kelly Dunigan, Tanjore K. Narayanan, Jogeshwar Mukherjee, Bingzhi Shi
Publikováno v:
Synapse. 37:64-70
The in vitro autoradiographic binding characteristics as well as in vivo imaging characteristics of a dopamine D2 receptor agonist, (R,S)-2-(N-propyl-N-1′-11C-propyl)amino-5-hydroxytetralin (11C-5-OH-DPAT), were studied. In 3H-spiperone assays usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84d69f196ffd566fe22baaebe554f05d
https://doi.org/10.1002/(sici)1098-2396(200007)37:1<64::aid-syn7>3.0.co
https://doi.org/10.1002/(sici)1098-2396(200007)37:1<64::aid-syn7>3.0.co
Publikováno v:
Synapse. 38:71-79
[18F]Fallypride is a highly selective, high-affinity dopamine D-2 receptor ligand. The high affinity, KD = 30 pM, makes it a suitable candidate for visualizing both striatal and extrastriatal binding in the brain. In this work, dynamic PET studies of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c10fed271fd88ff2e9cb44e45fe2a39
https://doi.org/10.1002/1098-2396(200010)38:1<71::aid-syn8>3.0.co
https://doi.org/10.1002/1098-2396(200010)38:1<71::aid-syn8>3.0.co
Autor:
Cristian Constantinescu, Divya Majji, Jogeshwar Mukherjee, Bingzhi Shi, Tanjore K. Narayanan, Jasmeet Kaur, Mohamed T. Nour, Min-Liang Pan
Publikováno v:
Synapse. 71:e21950
Imaging the high-affinity, functional state (HA) of dopamine D2 and D3 receptors has been pursued in PET imaging studies of various brain functions. We report further evaluation of 18F-5-OH-FPPAT, and the newer 18F-5-OH-FHXPAT and 18F-7-OH-FHXPAT. Sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a6283c8cc5ecf2ccd57f32a048d6ec
https://doi.org/10.1002/syn.21950
https://doi.org/10.1002/syn.21950