Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tanja Wader"'
Autor:
Jörg Vollmer, Christian Schetter, Arthur M. Krieg, Tanja Wader, Meike Wüllner, Heather L. Davis, Risini D. Weeratna, Andrea Kritzler, Ming Liu, Marion Jurk
Publikováno v:
Journal of Leukocyte Biology. 76:585-593
Synthetic phosphorothioate oligodeoxynucleotides (ODN) bearing unmethylated CpG motifs can mimic the immune-stimulatory effects of bacterial DNA and are recognized by Toll-like receptor 9 (TLR9). Past studies have demonstrated that nucleotide modific
Autor:
Christian Schetter, Tanja Wader, Arthur M. Krieg, Jörg Vollmer, Meike Wüllner, Jan Stenvang Jepsen, Eugen Uhlmann, Marion Jurk
Publikováno v:
Oligonucleotides. 14:23-31
Locked nucleic acid (LNA) is an RNA derivative that when introduced into oligodeoxynucleotides (ODN), mediates high efficacy and stability. CpG ODNs are potent immune stimulators and are recognized by toll-like receptor-9 (TLR9). Some phosphorothioat
Autor:
Sibylle Tluk, Tanja Wader, Heather L. Davis, Jörg Vollmer, Meike Laucht, Ming Liu, Paul J. Payette, Risini D. Weeratna, Arthur M. Krieg, Christian Schetter, Marion Jurk
Publikováno v:
European Journal of Immunology. 34:251-262
Oligodeoxynucleotides (ODN) with unmethylated deoxycytidyl-deoxyguanosine (CpG) dinucleotides (CpG ODN) mimic the immunostimulatory activity of bacterial DNA and are recognized by the Toll-like receptor 9 (TLR9). CpG ODN of the B-Class stimulate stro
Autor:
Tanja Wader, Alexandra Forsbach, Sybille Tluk, Ulrike Samulowitz, Christian Müller, Eugen Uhlmann, Hans-Peter Hofmann, Rainer Curdt, Anja Podszuweit, Bernhard O. Noll, Jörg Vollmer, Kirsten Völp, Angela Lohner, Claudia Schmitz
Publikováno v:
Nucleic acid therapeutics. 21(6)
The toll-like receptors (TLRs) 7, 8, and 9 stimulate innate immune responses upon recognizing pathogen nucleic acids. Certain GU- or AU-rich RNA sequences were described to differentiate between human TLR7- and TLR8-mediated immune effects. Those sin
Autor:
Jörg Vollmer, Arthur M. Krieg, Bernhard O. Noll, Christian Schetter, Tanja Wader, Eugen Uhlmann, Bettina Schulte, Marion Jurk, Andrea Kritzler
Publikováno v:
Immunobiology. 209(1-2)
Synthetic oligodeoxynucleotides (ODN) containing unmethylated deoxycytosine-deoxyguanosine (CpG) motifs are very potent inducers of the innate immune system, mimicking the effects of bacterial DNA. CpG ODN are recognized by Toll-like receptor 9 (TLR9
Autor:
Robert Rankin, Andrea Janosch, Jörg Vollmer, Marion Jurk, Tanja Wader, Hanna Hartmann, Arthur M. Krieg, Ulrike Samulowitz, Christian Schetter
Publikováno v:
Antimicrobial agents and chemotherapy. 48(6)
To investigate their potential mechanisms of action, the nucleoside analogue ribavirin and a TLR9 agonist were compared. The CpG oligodeoxynucleotides (ODN) demonstrated strong TLR9-related Th1-type effects, and ribavirin appeared only to mediate sig
Autor:
Jörg Vollmer, Jan Stenvang Jepsen, Eugen Uhlmann, Christian Schetter, Marion Jurk, Tanja Wader, Meike Wüllner, Arthur M. Krieg
Publikováno v:
Oligonucleotides; Spring2004, Vol. 14 Issue 1, p23-31, 9p