Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Tanja Petnicki‐Ocwieja"'
Autor:
Tanja Petnicki-Ocwieja, Julie E McCarthy, Urmila Powale, P Kent Langston, Jennifer D Helble, Linden T Hu
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011886 (2023)
Borrelia burgdorferi (Bb), the causative agent of Lyme disease, establishes a long-term infection and leads to disease manifestations that are the result of host immune responses to the pathogen. Inflammatory manifestations resolve spontaneously desp
Externí odkaz:
https://doaj.org/article/4d2f34deaaed43e292d0514d8b44589a
Autor:
Tanja Petnicki-Ocwieja, Alicia S DeFrancesco, Erin Chung, Courtney T Darcy, Roderick T Bronson, Koichi S Kobayashi, Linden T Hu
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17414 (2011)
The internalization of Borrelia burgdorferi, the causative agent of Lyme disease, by phagocytes is essential for an effective activation of the immune response to this pathogen. The intracellular, cytosolic receptor Nod2 has been shown to play varyin
Externí odkaz:
https://doaj.org/article/5050b70fc2304470abf52e0b25696394
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12871 (2010)
Toll-like receptor (TLR)-2/TLR1 heterodimers recognize bacterial lipopeptides and initiate the production of inflammatory mediators. Adaptors and co-receptors that mediate this process, as well as the mechanisms by which these adaptors and co-recepto
Externí odkaz:
https://doaj.org/article/9d23752ba1ba4485bfd9adf1da49688f
Autor:
Tanja Petnicki‐Ocwieja, Bijaya Sharma, Urmila Powale, Devesh Pathak, Shumin Tan, Linden T. Hu
Publikováno v:
Traffic (Copenhagen, Denmark)REFERENCES. 23(12)
Intracellular compartmentalization of ligands, receptors and signaling molecules has been recognized as an important regulator of inflammation. The toll-like receptor (TLR) 2 pathway utilizes the trafficking molecule adaptor protein 3 (AP-3) to activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948f04a9349bb97217656f419011362a
https://pubmed.ncbi.nlm.nih.gov/36224049
https://pubmed.ncbi.nlm.nih.gov/36224049
Publikováno v:
The Journal of Immunology. 195:4331-4340
Innate immune engagement results in the activation of host defenses that produce microbe-specific inflammatory responses. A long-standing interest in the field of innate immunity is to understand how varied host responses are generated through the si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b69aef4aece529806bf9966f8adefd
https://doi.org/10.4049/jimmunol.1501268
https://doi.org/10.4049/jimmunol.1501268
Autor:
Tanja Petnicki-Ocwieja, Linden T. Hu
Publikováno v:
Methods in Molecular Biology ISBN: 9781493973828
Methods Mol Biol
Methods Mol Biol
Phagosomal compartments are critical in microbial defense as vesicles that degrade invading organisms. In a broader context, vesicular trafficking plays an important role in shuttling many different types of cargo that are critical for proper functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e851dfaeae58b1859f499fa513655b
https://doi.org/10.1007/978-1-4939-7383-5_25
https://doi.org/10.1007/978-1-4939-7383-5_25
Autor:
Alice Bedugnis, Tanja Petnicki-Ocwieja, Maria Ballesteros, Stephen C. Bunnell, Linden T. Hu, Tess L. Killpack, Lester Kobzik
Phagocytosis of the Lyme disease-causing pathogen Borrelia burgdorferi has been shown to be important for generating an inflammatory response to the pathogen. As a result, understanding the mechanisms of phagocytosis has been an area of great interes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7730dd292710a3952b087532d8f64900
https://europepmc.org/articles/PMC5607427/
https://europepmc.org/articles/PMC5607427/
Autor:
Xin Li, David I. Acosta, Erin Chung, Laurie T. Ramos, Sanjukta Ghosh, Lester Kobzik, Linden T. Hu, Tanja Petnicki-Ocwieja, Ok Sarah Shin
Publikováno v:
Infection and Immunity. 81:402-410
TRIF is an adaptor molecule important in transducing signals from intracellularly signaling Toll-like receptor 3 (TLR3) and TLR4. Recently, TLR2 was found to signal from intracellular compartments. Using a synthetic ligand for TLR2/1 heterodimers, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee50cb5d39d8a12b5987aee153ebb41
https://doi.org/10.1128/iai.00890-12
https://doi.org/10.1128/iai.00890-12
Publikováno v:
Journal of Molecular Medicine. 90:15-24
The human intestine harbors a large number of bacteria that are constantly interacting with the intestinal immune system, eliciting non-pathological basal level immune responses. Increasing evidence points to dysbiosis of microbiota in the intestine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2701a5c9df6ff8269a68cdab72329ec
https://doi.org/10.1007/s00109-011-0802-y
https://doi.org/10.1007/s00109-011-0802-y