High on-aspirin treatment platelet reactivity and restenosis after percutaneous coronary intervention: results of the Intracoronary Stenting and Antithrombotic Regimen-ASpirin and Platelet Inhibition (ISAR-ASPI) Registry

Autor: Katharina Mayer, Gjin Ndrepepa, Mira Schroeter, Christopher Emmer, Isabell Bernlochner, Stefanie Schüpke, Senta Gewalt, Raphaela Hilz, John Joseph Coughlan, Alp Aytekin, Clarissa Heyken, Tanja Morath, Heribert Schunkert, Karl-Ludwig Laugwitz, Dirk Sibbing, Adnan Kastrati

Publikováno v: Clinical Research in Cardiology.

Objective The aim of this study was to assess the association between high on-aspirin treatment platelet reactivity (HAPR) and the subsequent risk of restenosis after percutaneous coronary intervention (PCI) with predominantly drug-eluting stents. Ba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a3e0914dfb4a2bcc6940b40209fbe29
https://doi.org/10.1007/s00392-023-02161-z

Efficacy and Safety of Ticagrelor Versus Prasugrel in Women and Men with Acute Coronary Syndrome: A Pre-specified, Sex-Specific Analysis of the ISAR-REACT 5 Trial

Autor: Karl-Ludwig Laugwitz, Heribert Schunkert, Bernhard Witzenbichler, Senta Gewalt, Katharina Mayer, Jochen Wöhrle, Tanja Morath, Maurizio Menichelli, Gjin Ndrepepa, Katharina Hoppe, Stefanie Schüpke, Franz-Josef Neumann, Adnan Kastrati, Isabell Bernlochner, Gert Richardt, Costanza Pellegrini, Shqipdona Lahu

Publikováno v: Journal of atherosclerosis and thrombosis. 29(5)

AIM Sex-specific analyses of direct head-to-head comparisons between newer P2Y12 inhibitors are limited. This study was conducted to assess the efficacy and safety of ticagrelor versus prasugrel in women and men with acute coronary syndromes (ACS) pl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d57d634491fb78726530e8dcc96d6f
https://pubmed.ncbi.nlm.nih.gov/33867409

Comparison of Vascular Closure Devices Versus Manual Compression After Femoral Artery Puncture in Women

Autor: Sandra Helde, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati, Massimiliano Fusaro, Sebastian Kufner, Robert A. Byrne, Petra Hoppmann, Ilka Ott, Senta Gewalt, Julia Hieber, Katharina Mayer, Salvatore Cassese, Tanja Morath, Tareq Ibrahim, Katharina Hoppe, Lorenz Bott-Flügel, Stefanie Schüpke, Roland Schmidt

Publikováno v: Circulation: Cardiovascular Interventions. 11

Background: The value of vascular closure devices (VCD) in women undergoing transfemoral catheterization has not been sufficiently investigated. Methods and Results: This is a sex-specific analysis of 1395 women enrolled in a large-scale, randomized,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b428a717ab458d7c400a74c35dbffaff
https://doi.org/10.1161/circinterventions.117.006074

Validation of the DAPT score in patients randomized to 6 or 12 months clopidogrel after predominantly second-generation drug-eluting stents

Autor: Stefanie Schulz-Schüpke, Marcus Fischer, Franz-Josef Neumann, Tom Adriaenssens, Adnan Kastrati, Raphaela Lohaus, Anna Lena Lahmann, Sebastian Kufner, Isabell Bernlochner, Yaling Han, Claudius Jacobshagen, Heribert Schunkert, Roisin Colleran, Michael Maeng, Jonathan Michel, Katharina Mayer, Bernhard Zrenner, Jochen Wöhrle, Ralph Tölg, Jurriën M. ten Berg, Roberto Emmer, Karl-Ludwig Laugwitz, Annabelle Wolk, Tanja Morath, Tareq Ibrahim, Robert A. Byrne, Julinda Mehilli, Daniele Giacoppo, Melchior Seyfarth, Yukinori Harada

Publikováno v: Harada, Y, Michel, J, Lohaus, R, Mayer, K, Emmer, R, Lahmann, A L, Colleran, R, Giacoppo, D, Wolk, A, Ten Berg, J M, Neumann, F-J, Han, Y, Adriaenssens, T, Tölg, R, Seyfarth, M, Maeng, M, Zrenner, B, Jacobshagen, C, Wöhrle, J, Kufner, S, Morath, T, Ibrahim, T, Bernlochner, I, Fischer, M, Schunkert, H, Laugwitz, K-L, Mehilli, J, Byrne, R A, Kastrati, A & Schulz-Schüpke, S 2017, ' Validation of the DAPT score in patients randomized to 6 or 12 months clopidogrel after predominantly second-generation drug-eluting stents ', Thrombosis and Haemostasis, vol. 117, no. 10, pp. 1989-1999 . https://doi.org/10.1160/TH17-02-0101

SummaryThe DAPT score is a recently-proposed decision tool for guiding optimal duration of dual antiplatelet therapy (DAPT). It showed modest accuracy in prior derivation and validation cohorts of patients with ≥12 months DAPT. This study was aimed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065b925791478b9ac29cf1e65b861c2b
https://pure.au.dk/portal/da/publications/validation-of-the-dapt-score-in-patients-randomized-to-6-or-12-months-clopidogrel-after-predominantly-secondgeneration-drugeluting-stents(5e705802-3b6c-4d48-9989-c3ab929b2eb6).html

Prasugrel plus bivalirudin vs. clopidogrel plus heparin in patients with ST-segment elevation myocardial infarction

Autor: Stefanie, Schulz, Gert, Richardt, Karl-Ludwig, Laugwitz, Tanja, Morath, Julia, Neudecker, Petra, Hoppmann, Roxana, Mehran, Anthony H, Gershlick, Ralph, Tölg, K, Anette Fiedler, Mohamed, Abdel-Wahab, Sebastian, Kufner, Simon, Schneider, Heribert, Schunkert, Tareq, Ibrahim, Julinda, Mehilli, Adnan, Kastrati

Publikováno v: European Heart Journal. 35:2285-2294

Aims Whether prasugrel plus bivalirudin is a superior strategy to unfractionated heparin plus clopidogrel in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) has never been a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcca1ea42207f02cf53ec10c23dd13c0
https://doi.org/10.1093/eurheartj/ehu182