Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tanja Minz"'
Autor:
Jörg Duschmalé, Adrian Schäublin, Erik Funder, Steffen Schmidt, Łukasz J. Kiełpiński, Helle Nymark, Klaus Jensen, Troels Koch, Martina Duschmalé, Erich Koller, Marianne Ravn Møller, Simone Schadt, Christophe Husser, Andreas Brink, Sabine Sewing, Tanja Minz, Jesper Wengel, Konrad Bleicher, Meiling Li
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 176-188 (2022)
The introduction of sulfur into the phosphate linkage of chemically synthesized oligonucleotides creates the stereocenters on phosphorus atoms. Researchers have valued the nature of backbone stereochemistry and early on investigated drug properties f
Externí odkaz:
https://doaj.org/article/129e910e0f0444d193c51f62a0777c79
Autor:
Sabine Sewing, Franziska Boess, Annie Moisan, Cristina Bertinetti-Lapatki, Tanja Minz, Maj Hedtjaern, Yann Tessier, Franz Schuler, Thomas Singer, Adrian B Roth
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159431 (2016)
Single stranded oligonucleotides (SSO) represent a novel therapeutic modality that opens new space to address previously undruggable targets. In spite of their proven efficacy, the development of promising SSO drug candidates has been limited by repo
Externí odkaz:
https://doaj.org/article/cc5d924443744c99be2c142b2f6b51f5
Autor:
Filippo Sladojevich, Remo Gamboni, Tanja Minz, Philippe Ringler, Rainer Alex, Sabine Kux van Geijtenbeek, Michaela Portmann, Axel Ducret, Matthias E. Lauer, Ravi Jagasia, Eric-André Kusznir, Bettina Nordbo, Sabine Sewing, Michael Keller, Nikhil J. Pandya, Erich Koller, Philip Grossen, Marco Berrera, Martina Brigitte Duschmalé, Sylwia Huber, Marianne Lerbech Jensen
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 158:198-210
The natural capacity of extracellular vesicles (EVs) to transport their payload to recipient cells has raised big interest to repurpose EVs as delivery vehicles for xenobiotics. In the present study, bovine milk-derived EVs (BMEVs) were investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d661697ef6bf27a8c7b0b3cba4f4e4
https://doi.org/10.1016/j.ejpb.2020.11.012
https://doi.org/10.1016/j.ejpb.2020.11.012
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2036
The mechanisms of antisense oligonucleotide-induced liver toxicity are still poorly understood. Assessment of the hepatic safety profile is currently mostly investigated directly in rodent studies. A predictive preclinical in vitro model that is capt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1dcf5c0563c34dc62d2fb788bc826d75
https://pubmed.ncbi.nlm.nih.gov/31410802
https://pubmed.ncbi.nlm.nih.gov/31410802
Publikováno v:
Methods in Molecular Biology ISBN: 9781493996698
The mechanisms of antisense oligonucleotide-induced liver toxicity are still poorly understood. Assessment of the hepatic safety profile is currently mostly investigated directly in rodent studies. A predictive preclinical in vitro model that is capt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c746cf29e940bdbe70646b43f6d19d7
https://doi.org/10.1007/978-1-4939-9670-4_15
https://doi.org/10.1007/978-1-4939-9670-4_15
Autor:
Maj Hedtjaern, Sabine Sewing, Franziska Boess, Annie Moisan, Franz Schuler, Tanja Minz, Cristina Bertinetti-Lapatki, Yann Tessier, Adrian Roth, Thomas Singer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 7, p e0159431 (2016)
PLoS ONE, Vol 11, Iss 7, p e0159431 (2016)
Single stranded oligonucleotides (SSO) represent a novel therapeutic modality that opens new space to address previously undruggable targets. In spite of their proven efficacy, the development of promising SSO drug candidates has been limited by repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c558d594152e0bbe85afb49e8a96e40
http://europepmc.org/articles/PMC4956313
http://europepmc.org/articles/PMC4956313
Publikováno v:
Journal of Microbiological Methods. 79:232-237
Multi-drug-resistant bacteria can cause serious infections that are extremely difficult to treat. Bacterial efflux pumps are known to contribute to multi-drug resistance and, thus, constitute a promising target for novel antibacterial agents. Resazur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95732c7e4af691cfc8b88bab58e44db4
https://doi.org/10.1016/j.mimet.2009.09.021
https://doi.org/10.1016/j.mimet.2009.09.021