Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Tanja M. Wrodnigg"'
Autor:
Philipp Materna, David Illek, Katrin Unger, Martin Thonhofer, Tanja M. Wrodnigg, Anna Maria Coclite
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 154:533-541
The aim of this work is to investigate if vinyl-modified carbohydrate compounds are suitable monomers for thin film polymerization via chemical vapor deposition in a proof-of-concept study. Synthetic carbohydrate-based polymers are explored as biodeg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f31b9491a239ef7914b291937ca182c
https://doi.org/10.1007/s00706-022-03015-6
https://doi.org/10.1007/s00706-022-03015-6
Autor:
Andreas Wolfsgruber, Martin Thonhofer, Patrick Weber, Seyed A. Nasseri, Roland Fischer, Michael Schalli, Arnold E. Stütz, Stephen G. Withers, Tanja M. Wrodnigg
Publikováno v:
Molecules, Vol 25, Iss 20, p 4618 (2020)
The scope of a series of N-alkylated iminosugar based inhibitors in the d-gluco as well as d-xylo configuration towards their interaction with human lysosomal β-glucocerebrosidase has been evaluated. A versatile synthetic toolbox has been developed
Externí odkaz:
https://doaj.org/article/3916536a34194b1ab1b2a753aade4f93
Autor:
Patrick Weber, Martin Thonhofer, Summer Averill, Gideon J. Davies, Andres Gonzalez Santana, Philipp Müller, Seyed A. Nasseri, Wendy A. Offen, Bettina M. Pabst, Eduard Paschke, Michael Schalli, Ana Torvisco, Marion Tschernutter, Christina Tysoe, Werner Windischhofer, Stephen G. Withers, Andreas Wolfsgruber, Tanja M. Wrodnigg, Arnold E. Stütz
Publikováno v:
Molecules, Vol 25, Iss 17, p 4025 (2020)
Glycosidase inhibitors have shown great potential as pharmacological chaperones for lysosomal storage diseases. In light of this, a series of new cyclopentanoid β-galactosidase inhibitors were prepared and their inhibitory and pharmacological chaper
Externí odkaz:
https://doaj.org/article/25403e0b400e40b799edabad23624a55
Publikováno v:
The Chemical Record. 21:2980-2989
A short survey on selected β-galactosidase inhibitors as potential pharmacological chaperones for GM1 -gangliosidosis and Morquio B associated mutants of human lysosomal β-galactosidase is provided highlighting recent developments in this particula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5174053ce747c4bbce6d69219deef9ff
https://doi.org/10.1002/tcr.202100269
https://doi.org/10.1002/tcr.202100269
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 1096-1104 (2015)
The Amadori rearrangement was employed for the synthesis of C-glycosyl-type D-mannoside analogues, namely 1-propargylamino- and 1-phenylamino-1-deoxy-α-D-manno-heptopyranose. They were investigated as ligands of type 1-fimbriated E. coli bacteria by
Externí odkaz:
https://doaj.org/article/e7ab485f6c034e52b8e1d18c035505a5
Publikováno v:
Organometallics
A convenient synthetic method to obtain d-galactose-substituted acylsilanes and acylgermanes is described. These acyl group 14 compounds are easily accessible in good yields. Their structural properties were analyzed by a combination of NMR, single c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434c2f59a1bde12da953293384503a27
https://doi.org/10.1021/acs.organomet.0c00753
https://doi.org/10.1021/acs.organomet.0c00753
Autor:
Katrin Pansy, Julia Feichtinger, Barbara Ehall, Barbara Uhl, Miriam Sedej, David Roula, Beata Pursche, Axel Wolf, Manuel Zoidl, Elisabeth Steinbauer, Verena Gruber, Hildegard T Greinix, Katharina T. Prochazka, Gerhard G. Thallinger, Akos Heinemann, Christine Beham-Schmid, Peter Neumeister, Tanja M. Wrodnigg, Karoline Fechter, Alexander JA. Deutsch
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4740 (2019)
In tumor cells of more than 20 different cancer types, the CXCR4-CXCL12-axis is involved in multiple key processes including proliferation, survival, migration, invasion, and metastasis. Since data on this axis in diffuse large B cell lymphoma (DLBCL
Externí odkaz:
https://doaj.org/article/5cd101c29c5549cba988f054225a9340
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 1619-1629 (2012)
The Amadori rearrangement was investigated as a potential method for the conjugation of carbohydrate moieties to suitable amino components. Starting from selected aldoheptoses, which are readily available by means of the Kiliani–Fischer C-elongatio
Externí odkaz:
https://doaj.org/article/b7c29bdf746d4e1ebe4dec15ff601680
Autor:
Patrick Weber, Seyed A. Nasseri, Bettina M. Pabst, Ana Torvisco, Philipp Müller, Eduard Paschke, Marion Tschernutter, Werner Windischhofer, Stephen G. Withers, Tanja M. Wrodnigg, Arnold E. Stütz
Publikováno v:
Molecules, Vol 23, Iss 3, p 708 (2018)
From 1,2;3,4-di-O-isopropylidene-d-galactopyranose, a preliminary series of highly functionalized amino(hydroxymethyl)cyclopentanes was easily available. These amine-containing basic carbasugars featuring the d-galacto configuration are potent inhibi
Externí odkaz:
https://doaj.org/article/a27bac4e4727409bbaf742aa4e0e9f59
Publikováno v:
Chemical record (New York, N.Y.). 21(11)
A short survey on selected β-galactosidase inhibitors as potential pharmacological chaperones for G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9e4710551ee6832b830acd5720c8a17
https://pubmed.ncbi.nlm.nih.gov/34816592
https://pubmed.ncbi.nlm.nih.gov/34816592