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pro vyhledávání: '"Tanja Linnerz"'
Autor:
Tanja Linnerz, Yih Jian Sung, Leah Rolland, Jonathan W. Astin, Nicola Dalbeth, Christopher J. Hall
Publikováno v:
Genes, Vol 13, Iss 12, p 2179 (2022)
Gout is caused by elevated serum urate leading to the deposition of monosodium urate (MSU) crystals that can trigger episodes of acute inflammation. Humans are sensitive to developing gout because they lack a functional urate-metabolizing enzyme call
Externí odkaz:
https://doaj.org/article/fb40bd95c7f54da19ec5e39ea2d6b449
Autor:
Tanja Linnerz, Christopher J. Hall
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The immediate and natural reaction to both infectious challenges and sterile insults (wounds, tissue trauma or crystal deposition) is an acute inflammatory response. This inflammatory response is mediated by activation of the innate immune system lar
Externí odkaz:
https://doaj.org/article/ef15b31097ab421eaf3bc27d451f8542
Autor:
Jean-François Denis, Mannekomba R. Diagbouga, Filippo Molica, Aurélie Hautefort, Tanja Linnerz, Masakatsu Watanabe, Sylvain Lemeille, Julien Y. Bertrand, Brenda R. Kwak
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Shear stress, a blood flow-induced frictional force, is essential in the control of endothelial cell (EC) homeostasis. High laminar shear stress (HLSS), as observed in straight parts of arteries, assures a quiescent non-activated endothelium through
Externí odkaz:
https://doaj.org/article/d4e39aa6517b4912b2f208c2ef0119b3
Autor:
Christopher J. Hall, Tanja Linnerz, Manju Kanamala, Nicola Dalbeth, Zimei Wu, Jonathan W. Astin
Publikováno v:
Journal of Visualized Experiments.
Zebrafish (Danio rerio) larvae have developed into a popular model to investigate host-pathogen interactions and the contribution of innate immune cells to inflammatory disease due to their functionally conserved innate immune system. They are also w