Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tanja Krainz"'
Autor:
Tanja Krainz, Michael M. Gaschler, Chaemin Lim, Joshua R. Sacher, Brent R. Stockwell, Peter Wipf
Publikováno v:
ACS Central Science, Vol 2, Iss 9, Pp 653-659 (2016)
Externí odkaz:
https://doaj.org/article/b6a7bc61845048079b5d98232cfd38dc
Autor:
Christian J. Bettencourt, Tanja Krainz, Sharon Chow, Brendan T. Parr, William F. Tracy, Paul V. Bernhardt, Huw M. L. Davies, Craig M. Williams
Publikováno v:
Organic Letters. 24:9290-9295
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::494d865656f2ce77bfdcfe02301583be
https://doi.org/10.1021/acs.orglett.2c03869
https://doi.org/10.1021/acs.orglett.2c03869
Publikováno v:
Organic letters. 21(21)
Phorbol esters are long regarded as tumor promotors, due to protein kinase C (PKC) activation, but more recently higher oxidized natural derivatives have been shown to display antitumor activity. Given the synthetic difficulty, systematic non-natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573104c716b108b536b371678679b84d
https://pubmed.ncbi.nlm.nih.gov/31626552
https://pubmed.ncbi.nlm.nih.gov/31626552
Autor:
Joshua R. Sacher, Michael M. Gaschler, Brent R. Stockwell, Peter Wipf, Chaemin Lim, Tanja Krainz
Publikováno v:
ACS Central Science, Vol 2, Iss 9, Pp 653-659 (2016)
ACS Central Science
ACS Central Science
Discovering compounds and mechanisms for inhibiting ferroptosis, a form of regulated, nonapoptotic cell death, has been of great interest in recent years. In this study, we demonstrate the ability of XJB-5-131, JP4-039, and other nitroxide-based lipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90afe9437dc161a315e4f5477a093dd
https://doaj.org/article/b6a7bc61845048079b5d98232cfd38dc
https://doaj.org/article/b6a7bc61845048079b5d98232cfd38dc
Autor:
Lina Du, Robert S. B. Clark, Taber S. Maskrey, Hülya Bayır, Joel S. Greenberger, Peter Wipf, Simon C. Watkins, Tanja Krainz, Michael J. Calderon, Michael W. Epperly, Andrew M. Lamade
Publikováno v:
ACS chemical biology. 13(10)
The poly(ADP-ribose) polymerase (PARP) family of enzymes plays a crucial role in cellular and molecular processes including DNA damage detection and repair, and transcription; indeed, PARP inhibitors are under clinical evaluation as chemotherapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e797176401b8a18a53066d4388b6cea
https://pubmed.ncbi.nlm.nih.gov/30184433
https://pubmed.ncbi.nlm.nih.gov/30184433
Autor:
Craig M. Williams, Tanja Krainz, Sharon Chow, Paul V. Bernhardt, Huw M. L. Davies, Glen M. Boyle, Natasa Korica, Peter G. Parsons
Publikováno v:
European Journal of Organic Chemistry. 2016:41-44
An efficient method to directly access the bicyclo[5.3.0]decane core was achieved by rhodium-catalyzed reaction of a novel donor-acceptor cyclopentenyl diazocarboxylate with a variety of furans. As this motif is commonly found within bioactive antitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6594fda049ee838b559bbbd21da57c34
https://doi.org/10.1002/ejoc.201501271
https://doi.org/10.1002/ejoc.201501271
Autor:
Tanja Krainz
Phorbol esters belong to the family of tigliane diterpenes isolated from Croton tiglium, a member of the Euphorbiaceae and Thymelaeaceae plants. Since its isolation in 1935 phorbol has had a rapid rise to fame as a tumor promoter via protein kinase C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33dd23135bc9e60330be80878ce540c6
https://doi.org/10.14264/uql.2017.740
https://doi.org/10.14264/uql.2017.740
Autor:
Joel S. Greenberger, Michael W. Epperly, Joshua R. Sacher, Tanja Krainz, Xiaolin Zhang, Renee Fisher, Peter Wipf, Mary Liang, Hong Wang, Song Li
Background/aim Mitochondrial-targeted gramicidin S (GS)-nitroxide, JP4-039, has been demonstrated to be a potent radiation mitigator, and safe over a wide dose range. In addition, JP4-039 has organ-specific effectiveness when locally applied. Materia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5dbdea035292a3b75ade9c39fb45770
https://europepmc.org/articles/PMC5267945/
https://europepmc.org/articles/PMC5267945/
Autor:
Glen M. Boyle, Peter G. Parsons, Paul V. Bernhardt, Sharon Chow, Tanja Krainz, Huw M. L. Davies, Natasa Korica, Craig M. Williams
Publikováno v:
ChemInform. 47
An efficient method to directly access the bicyclo[5.3.0]decane core was achieved by rhodium-catalyzed reaction of a novel donor-acceptor cyclopentenyl diazocarboxylate with a variety of furans. As this motif is commonly found within bioactive antitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::300187862bdf80f38c3719d4fce04d2e
https://doi.org/10.1002/chin.201621142
https://doi.org/10.1002/chin.201621142
Publikováno v:
Organic Syntheses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd81052054ea84b9a0cba514c43097ff
https://doi.org/10.1002/0471264229.os092.21
https://doi.org/10.1002/0471264229.os092.21