Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tanja Jakos"'
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cysteine cathepsins are key regulators of the innate and adaptive arms of the immune system. Their expression, activity, and subcellular localization are associated with the distinct development and differentiation stages of immune cells. They promot
Externí odkaz:
https://doaj.org/article/4a37f084c1c74de3b174e1c148d09251
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1843 (2022)
Triple-negative breast cancer (TNBC) is a highly aggressive subset of breast cancer with limited therapeutic options. However, its immune evasion mechanisms, characterized by the over-expression of the immune checkpoint molecules PD-L1 and CD47, can
Externí odkaz:
https://doaj.org/article/0c0c000e95f14a93b9ce91d88c861e0e
Autor:
Hui Chen, Jun-Sheng Chen, Pameila Paerhati, Tanja Jakos, Si-Yi Bai, Jian-Wei Zhu, Yun-Sheng Yuan
Publikováno v:
Pharmaceutical Fronts, Vol 03, Iss 02, Pp e39-e49 (2021)
With the advancement of genetic engineering, monoclonal antibodies (mAbs) have made far-reaching progress in the treatment of various human diseases. However, due to the high cost of production, the increasing demands for antibody-based therapies hav
Externí odkaz:
https://doaj.org/article/7cbbe88c41094c0fb57fffbdbf68ca93
Publikováno v:
International Immunopharmacology. 113:109393
Hepatocellular carcinoma (HCC) accounts for ∼90 % of all liver cancer cases, which was the third most common cause of cancer death worldwide in 2020. Glypican-3 (GPC3) is highly and specifically expressed in HCC, which makes it a promising therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9359b45385027619da935f2e12457122
https://doi.org/10.1016/j.intimp.2022.109393
https://doi.org/10.1016/j.intimp.2022.109393
Autor:
Jianwei Zhu, Yunsheng Yuan, Chen Hui, Jun-Sheng Chen, Pameila Paerhati, Siyi Bai, Tanja Jakos
Publikováno v:
Pharmaceutical Fronts, Vol 03, Iss 02, Pp e39-e49 (2021)
With the advancement of genetic engineering, monoclonal antibodies (mAbs) have made far-reaching progress in the treatment of various human diseases. However, due to the high cost of production, the increasing demands for antibody-based therapies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1328b78bca8516a6206e91fb7218bb3a
http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1735145
http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1735145
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cysteine cathepsins are primarily involved in the degradation and recycling of proteins in endo-lysosomal compartments but are also gaining recognition as pivotal proteolytic contributors to various immune functions. Through their extracellular prote
Externí odkaz:
https://doaj.org/article/25bf861b8d7d4829a7bec15ae0905453
Autor:
Anja Pišlar, Ana Mitrović, Jerica Sabotič, Urša Pečar Fonović, Milica Perišić Nanut, Tanja Jakoš, Emanuela Senjor, Janko Kos
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1009013 (2020)
Over the last 2 decades, several coronaviruses (CoVs) have crossed the species barrier into humans, causing highly prevalent and severe respiratory diseases, often with fatal outcomes. CoVs are a large group of enveloped, single-stranded, positive-se
Externí odkaz:
https://doaj.org/article/96477989d53748a29882d5427c68c5f8