Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tanja Hinrichsen"'
Autor:
Barbara Dockhorn-Dworniczak, Juliane K. Dworniczak, Bernd Dworniczak, Tanja Hinrichsen, Oliver Wachter
Publikováno v:
LaboratoriumsMedizin. 40:313-322
The term liquid biopsy comprises methods of blood-based analysis of nucleic acids, which are increasingly under discussion in oncology and personalized medicine, and are already applied in individual cases. The analysis of tumor markers, which in cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::900f33309f39724281b2e7c9ae3ef0f7
https://doi.org/10.1515/labmed-2016-0035
https://doi.org/10.1515/labmed-2016-0035
Autor:
G Walter, Marion Subklewe, Tanja Hinrichsen, Karsten Spiekermann, Tobias Herold, V Groiß, Klaus H. Metzeler, Irmela Jeremias, Maja Rothenberg, Sebastian Tiedt, Stefan Fröhling, Michaela Grunert, O Wachter, Michela Carlet, H-G Klein, Stephanie Schneider, Nadine Sandhöfer, Alyssa B. Dufour, Wolfgang Hiddemann
Publikováno v:
Leukemia 29, 828-838 (2015)
In acute myeloid leukemia (AML), several signaling pathways such as the phosphatidylinositol-3-kinase/AKT and the mammalian target of rapamycin (PI3K/AKT/mTOR) pathway are deregulated and constitutively activated as a consequence of genetic and cytog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d1b9680440e1583a7236d1a20d4ccc
https://doi.org/10.1038/leu.2014.305
https://doi.org/10.1038/leu.2014.305
Autor:
Leticia Quintanilla-Martinez, Peter Klapthor, Irina Bonzheim, Falko Fend, Tanja Hinrichsen, Barbara Mankel, Oliver Wachter, Janine Schmidt
Publikováno v:
Blood. 125:2309-2311
To the editor: The understanding of the genetic basis of the myeloproliferative neoplasms has increased tremendously in the last few years.[1][1] In essential thrombocythemia (ET), 50% to 65% of the patients carry the JAK2 V617F mutation, whereas onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::101f2c7b50a821d2a79533897f251ce0
https://doi.org/10.1182/blood-2014-12-616847
https://doi.org/10.1182/blood-2014-12-616847
Publikováno v:
Transfusion Medicine and Hemotherapy. 40:196-206
With the introduction of the next generation sequencing (NGS) technologies, remarkable new diagnostic applications have been established in daily routine. Implementation of NGS is challenging in clinical diagnostics, but definite advantages and new d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ea71cb649b41dade1b8a134cf05514
https://doi.org/10.1159/000351267
https://doi.org/10.1159/000351267
Autor:
Monika Bühl-Göpfert, Tanja Hinrichsen
Publikováno v:
LaboratoriumsMedizin. 33:271-281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dbc40476d9de141788112c5ca9a56f1
https://doi.org/10.1515/jlm.2009.049
https://doi.org/10.1515/jlm.2009.049
Autor:
Konstanze Döhner, Eric Yung, Bob Argiropoulos, Tanja Hinrichsen, Cornelia Rudolph, Axel Schambach, Arnold Ganser, Florian Kuchenbauer, Brigitte Schlegelberger, Hartmut Döhner, Jessica Piper, Stephen Fung, Richard F. Schlenk, Christopher Baum, Michael Heuser, R. Keith Humphries
Publikováno v:
Blood. 110:1639-1647
Overexpression of wild-type MN1 is a negative prognostic factor in patients with acute myeloid leukemia (AML) with normal cytogenetics. We evaluated whether MN1 plays a functional role in leukemogenesis. We demonstrate using retroviral gene transfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582ed4fbb599c26bb6a369b499a299b8
https://doi.org/10.1182/blood-2007-03-080523
https://doi.org/10.1182/blood-2007-03-080523
Autor:
Sabine Hertz, Doris Steinemann, Anja Weigmann, Sarah Tauscher, Brigitte Schlegelberger, Peter Lichter, Thomas Becker, Tanja Hinrichsen, Jacobus Flik, B. Wiese, Peer Flemming, Ludwig Wilkens, Hans Kreipe, Britta Skawran, Luzie U. Wingen, Marcel Tauscher
Publikováno v:
Clinical Gastroenterology and Hepatology. 4:1283-1291
To gain more information about the molecular mechanisms leading to dedifferentiation of hepatocellular adenoma (HCA) and hepatocellular carcinoma (HCC), high-resolution array-based comparative genomic hybridization (array-CGH) was performed on 24 cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740729d21a07fbbbe3ec8e24fb8b3b5d
https://doi.org/10.1016/j.cgh.2006.07.010
https://doi.org/10.1016/j.cgh.2006.07.010
Publikováno v:
Blood. 128:5604-5604
A 75-year-old patient with slowly increasing polyneuropathy (PNP) (sensitive PNP, WHO°2), pre-existing for 6 months, in conjunction with a monoclonal gammopathy (IgG/kappa) is presented. Significant pre-existing conditions (for example, diabetes) do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b5c67399b9585b8f731c77caef21ab
https://doi.org/10.1182/blood.v128.22.5604.5604
https://doi.org/10.1182/blood.v128.22.5604.5604
Autor:
Sonja Beicht, Elke Kaminsky, Hanns-Georg Klein, Lutz T. Weber, Sabine Rath, Gertrud Strobl-Wildemann, Martin Alberer, Oliver Wachter, Tanja Hinrichsen, Julia Hoefele
Publikováno v:
Gene. 526(2)
Alport syndrome (ATS) is a progressive hereditary nephropathy characterized by hematuria and/or proteinuria with structural defects of the glomerular basement membrane. It can be associated with extrarenal manifestations (high-tone sensorineural hear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75739072bbe361dab52a140a0b32099
https://pubmed.ncbi.nlm.nih.gov/23732293
https://pubmed.ncbi.nlm.nih.gov/23732293
Autor:
Volker Groiß, Sebastian Tiedt, Nadine Sandhöfer, Karsten Spiekermann, Evelyn Zellmeier, Tanja Hinrichsen, Klaus H. Metzeler, Irmela Jeremias, Wolfgang Hiddemann, Oliver Wachter, Hanns-Georg Klein
Publikováno v:
Blood. 122:818-818
Background Despite the recent advances and better understanding of the biology of acute myeloid leukemia (AML), only little improvement was achieved in treatment and cure rates. One of the key signaling pathways known to be frequently deregulated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::054ceb4082e1e9ffdc6e426d0d44d27b
https://doi.org/10.1182/blood.v122.21.818.818
https://doi.org/10.1182/blood.v122.21.818.818