Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tanja Gesell"'
Autor:
Robert Konrat, Henrietta Papp, Janine Kimpel, Annika Rössler, Valéria Szijártó, Gábor Nagy, Mónika Madai, Safia Zeghbib, Anett Kuczmog, Zsófia Lanszki, Tanja Gesell, Zsuzsanna Helyes, Gábor Kemenesi, Ferenc Jakab, Eszter Nagy
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background and purpose: The COVID-19 pandemic continues to pose challenges, especially with the emergence of new SARS-CoV-2 variants that are associated with higher infectivity and/or compromised protection afforded by the current vaccines. There is
Externí odkaz:
https://doaj.org/article/1344b9b57c71472b863d5a3266f4a64c
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9169 (2010)
BACKGROUND: SELEX is a well established in vitro selection tool to analyze the structure of ligand-binding nucleic acid sequences called aptamers. Genomic SELEX transforms SELEX into a tool to discover novel, genomically encoded RNA or DNA sequences
Externí odkaz:
https://doaj.org/article/1cf9d5863f194ef4ad60dcbb09e66ae4
Autor:
Gabor Nagy, Eszter Nagy, Zsófia Lanszki, Gábor Kemenesi, Tanja Gesell, Valéria Szijártó, Anett Kuczmog, Robert Konrat, Ferenc Jakab, Mónika Madai, Zsuzsanna Helyes, Safia Zeghbib, Henrietta Papp
BackgroundThe COVID-19 pandemic is an enormous threat for healthcare systems and economies worldwide that urgently demands effective preventive and therapeutic strategies. Unlike the development of vaccines and new drugs specifically targeting SARS-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b60aedf754e97209d88f22dd3df7577f
https://doi.org/10.1101/2020.09.15.296228
https://doi.org/10.1101/2020.09.15.296228
Autor:
Katy Schmidt, Graham Warren, Marco Sealey-Cardona, Tanja Gesell, Lars Demmel, Tatjana Hirschmugl, Gang Dong
Publikováno v:
Traffic. 15:613-629
The Sec16 homologue in Trypanosoma brucei has been identified and characterized. TbSec16 colocalizes with COPII components at the single endoplasmic reticulum exit site (ERES), which is next to the single Golgi stack in the insect (procyclic) form of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83cdc197691d1f07f47bb79dbfb8ff2f
https://doi.org/10.1111/tra.12170
https://doi.org/10.1111/tra.12170
Publikováno v:
Journal of Theoretical Biology. 334:162-172
Although the basic mechanics of evolution have been understood since Darwin, debate continues over whether macroevolutionary phenomena are driven by the fitness structure of genotype space or by ecological interaction. In this paper we propose a simp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4540eec9a98277e807c69fe976a12e80
https://doi.org/10.1016/j.jtbi.2013.05.030
https://doi.org/10.1016/j.jtbi.2013.05.030
Publikováno v:
Nucleic Acids Research
Evolutionarily conserved RNA secondary structures are a robust indicator of purifying selection and, consequently, molecular function. Evaluating their genome-wide occurrence through comparative genomics has consistently been plagued by high false-po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36302f9f06b2a915bdc121369b41e17
https://doi.org/10.1093/nar/gkt596
https://doi.org/10.1093/nar/gkt596
Publikováno v:
Molecular Biology and Evolution
Among the criteria to evaluate the performance of a phylogenetic method, robustness to model violation is of particular practical importance as complete a priori knowledge of evolutionary processes is typically unavailable. For studies of robustness
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a22d3ca73095dc19f8ace99aa799dc4
https://doi.org/10.1093/molbev/msr220
https://doi.org/10.1093/molbev/msr220
Publikováno v:
Bioinformatics
Motivation: Predicting RNA–RNA interactions is essential for determining the function of putative non-coding RNAs. Existing methods for the prediction of interactions are all based on single sequences. Since comparative methods have already been us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc3e102de21ee9d4649b94fbc85812a
https://doi.org/10.1093/bioinformatics/btq634
https://doi.org/10.1093/bioinformatics/btq634
Autor:
C. Lorenz, Bob Zimmermann, Tanja Gesell, Christina Waldsich, I. Bilusic, U. Schoeberl, Renée Schroeder, L. Rajkowitsch, A. von Haeseler
Publikováno v:
Nucleic Acids Research
An unexpectedly high number of regulatory RNAs have been recently discovered that fine-tune the function of genes at all levels of expression. We employed Genomic SELEX, a method to identify protein-binding RNAs encoded in the genome, to search for f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984d27791d6449c026dd68f832536714
https://doi.org/10.1093/nar/gkq032
https://doi.org/10.1093/nar/gkq032
Publikováno v:
Applied Mathematics and Computation. 196:221-235
In the present paper, we introduce a notion of a style representing abstract, complex objects having characteristics that can be represented as structured objects. Furthermore, we provide some mathematical properties of such styles. As a main result,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5001172222bedfd4051365225419c101
https://doi.org/10.1016/j.amc.2007.05.058
https://doi.org/10.1016/j.amc.2007.05.058