Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Tanja Freichel"'
1
Filament-based 3D-printing of placebo dosage forms using brittle lipid-based excipients
Autor: Moaaz Abdelhamid, Ioannis Koutsamanis, Carolina Corzo, Mira Maisriemler, Ana Belén Ocampo, Eyke Slama, Carolina Alva, Dirk Lochmann, Sebastian Reyer, Tanja Freichel, Sharareh Salar-Behzadi, Martin Spoerk
Publikováno v: International journal of pharmaceutics. 624
In order to expand the limited portfolio of available polymer-based excipients for fabricating three-dimensional (3D) printed pharmaceutical products, Lipid-based excipients (LBEs) have yet to be thoroughly investigated. The technical obstacle of LBE
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fe41b64f3fe362d19528e545913910
https://pubmed.ncbi.nlm.nih.gov/35839981
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2
Asymmetrically Branched Precision Glycooligomers Targeting Langerin
Autor: Laura Hartmann, Tanja Freichel, Andrea Grafmüller, Kira Neuhaus, Christoph Rademacher, Eike-Christian Wamhoff
Publikováno v: Biomacromolecules. 20:4088-4095
Asymmetrically branched precision glycooligomers are synthesized by solid-phase polymer synthesis for studying multivalent carbohydrate-protein interactions. Through the stepwise assembly of Fmoc-protected oligo(amidoamine) building blocks and Fmoc/D
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e39332eab9e02889f34b03372e680c7
https://doi.org/10.1021/acs.biomac.9b00906
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4
Sequence-Controlled Glycopolymers via Step-Growth Polymerization of Precision Glycomacromolecules for Lectin Receptor Clustering
Autor: Tanja Freichel, Morten F. Ebbesen, Christoph Gerke, Laura Hartmann, Dennis Jansen, Sophia Boden
Publikováno v: Biomacromolecules. 18:787-796
A versatile approach for the synthesis of sequence-controlled multiblock copolymers, using a combination of solid phase synthesis and step-growth polymerization by photoinduced thiol–ene coupling (TEC) is presented. Following this strategy, a serie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d906a2eaee418d3ecd4fd5ecaadc709
https://doi.org/10.1021/acs.biomac.6b01657
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6
Monodisperse Sequence-Controlled α-l-Fucosylated Glycooligomers and Their Multivalent Inhibitory Effects on LecB
Autor: Filip Kovacic, Nikolina Babic, Laura Hartmann, Tanja Freichel, Katharina Susanne Bücher
Publikováno v: Macromolecular bioscience. 18(12)
The opportunistic bacterium Pseudomonas aeruginosa, often exhibiting multiresistance against conventional antibiotics, expresses the lectin LecB that is suspected to be an important factor during biofilm formation via interactions with cell-surface p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45de2d9ad91ef4ecd6e36d505247b402
https://pubmed.ncbi.nlm.nih.gov/30408344
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7
Toward Orthogonal Preparation of Sequence-Defined Monodisperse Heteromultivalent Glycomacromolecules on Solid Support Using Staudinger Ligation and Copper-Catalyzed Click Reactions
Autor: Svenja Eierhoff, Laura Hartmann, Nicole L. Snyder, Tanja Freichel
Publikováno v: The Journal of organic chemistry. 82(18)
The investigation of heteromultivalent interactions of complex glycoligands and proteins is critical for understanding important biological processes and developing carbohydrate-based pharmaceutics. Synthetic glycomimetics, derived by mimicking compl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478fa518eec4ebca96ab16bb276f4af7
https://pubmed.ncbi.nlm.nih.gov/28845668
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