Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tanja Fisch"'
Autor:
Katarzyna Anna Ludwik, Lina Hellwig, Tanja Fisch, Jörg Contzen, Claudia Schaar, Philipp Mergenthaler, Harald Stachelscheid
Publikováno v:
Stem Cell Research, Vol 76, Iss , Pp 103377- (2024)
Bcl-2-associated X protein (BAX) and Blc-2 homologous antagonist killer 1 (BAK) are two pro-apoptotic members of BCL2 family. Here, two BAX/BAK double knock-out human induced pluripotent stem cell lines (iPSC) we generated using CRISPR-Cas9 to genera
Externí odkaz:
https://doaj.org/article/dd5a739942364f8e8de24e811ee7c18a
Autor:
Janine Cernoch, Tanja Fisch, Iris Fischer, Kristin Fischer, Anna Iwanska, Norman Krüger, Judit Küchler, Claudia Schaar, Sandra Schommer, Narasimha Telugu, Duncan Miller, Valeria Fernández Vallone, Andreas Kurtz, Petra Reinke, Sebastian Diecke, Harald Stachelscheid
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102406- (2021)
Focal segmental glomerulosclerosis (FSGS) is a major cause of familial nephrotic syndrome. We generated 20 induced pluripotent stem cell lines from patients diagnosed with FSGS. The iPSC lines include 8 female and 12 male lines and cover a donor age
Externí odkaz:
https://doaj.org/article/6483970034ec4e99bd13d0f0538933e2
Autor:
Iris Fischer, Judit Küchler, Claudia Schaar, Tanja Fisch, Janine Cernoch, Kristin Fischer, Valeria Fernández Vallone, Peter Kühnen, Harald Stachelscheid
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102417- (2021)
MIRAGE syndrome is a multisystem disorder caused by mutations in SAMD9 (sterile α motif domain-containing protein 9) with a high mortality in the first decade of life. We generated 2 human induced pluripotent stem cell lines from male children diagn
Externí odkaz:
https://doaj.org/article/f955f943d10e47d5a7358b2392ee170d
Autor:
Barbara Kropff, Christiane Burkhardt, Juliane Schott, Jens Nentwich, Tanja Fisch, William Britt, Michael Mach
Publikováno v:
PLoS Pathogens, Vol 8, Iss 10, p e1002999 (2012)
Herpes viruses persist in the infected host and are transmitted between hosts in the presence of a fully functional humoral immune response, suggesting that they can evade neutralization by antiviral antibodies. Human cytomegalovirus (HCMV) encodes a
Externí odkaz:
https://doaj.org/article/bf0213ac7c284047a3d2a83404089cb3
Autor:
Sonja Pötzsch, Nadja Spindler, Anna-Katharina Wiegers, Tanja Fisch, Pia Rücker, Heinrich Sticht, Nina Grieb, Tina Baroti, Florian Weisel, Thomas Stamminger, Luis Martin-Parras, Michael Mach, Thomas H Winkler
Publikováno v:
PLoS Pathogens, Vol 7, Iss 8, p e1002172 (2011)
Human cytomegalovirus (HCMV), a herpesvirus, is a ubiquitously distributed pathogen that causes severe disease in immunosuppressed patients and infected newborns. Efforts are underway to prepare effective subunit vaccines and therapies including anti
Externí odkaz:
https://doaj.org/article/6dde1471881a464cb3b83bc021578086
Autor:
Inga Nehlmeier, Miriam Kiene, Jan Münch, Christina B. Karsten, David Palesch, Andreas Urbanczyk, Stefan Pöhlmann, Stephanie Bertram, Imke Steffen, Tanja Fisch, Francesca Chiodi, Kerstin Gnirß, Andrea Marzi
Publikováno v:
Virology. 433:73-84
Many SIV isolates can employ the orphan receptor GPR15 as coreceptor for efficient entry into transfected cell lines, but the role of endogenously expressed GPR15 in SIV cell tropism is largely unclear. Here, we show that several human B and T cell l
Autor:
Peter Yakowec, Jin Tang, Violeta Yu, Alexander M. Long, Ralf Schwandner, Tanja Fisch, Josie Han Lee, Renee Emkey, Markus Hierl, Hao Chen
Publikováno v:
SLAS Discovery. 17:27-38
Lysine demethylase 1 (LSD1) and Jumonji C domain-containing oxygenase D2C (JMJD2C) participate in regulating the methylation status of histone H3 lysine residues. In some contexts, LSD1 and JMJD2C activity causes enhanced cellular proliferation, whic
Autor:
David F. Smith, Anne Dell, Bérangère Tissot, Stefan Pöhlmann, Kurt Drickamer, Alex S. Powlesland, Maureen E. Taylor, Tanja Fisch
Publikováno v:
Journal of Biological Chemistry
LSECtin is a member of the C-type lectin family of glycan-binding receptors that is expressed on sinusoidal endothelial cells of the liver and lymph nodes. In order to compare the sugar- and pathogen-binding properties of LSECtin with those of relate
Autor:
Andrea Marzi, Ronald C. Desrosiers, Chawaree Chaipan, Mary Carrington, Stefan Pöhlmann, Robert W. Doms, Daniel A. Mitchell, Tanja Fisch
Publikováno v:
Virology. 368:322-330
The C-type lectin DC-SIGN binds to oligosaccharides on the human and simian immunodeficiency virus (HIV, SIV) envelope glycoproteins and promotes infection of susceptible cells. Here, we show that DC-SIGN recognizes glycans involved in SIV sensitivit
Autor:
Robert Hofmeister, Nadja Prang, Sandrine d’Argouges, Klaus Brischwein, JoAnn Suzich, Christian Brandl, Cornelia Haas, Peter Kufer, Tanja Fisch, Ralf C. Bargou, Patrick A. Baeuerle
Publikováno v:
Cancer Immunology, Immunotherapy. 56:1551-1563
BiTE molecules comprise a new class of bispecific single-chain antibodies redirecting previously unstimulated CD8+ and CD4+ T cells for the elimination of target cells. One example is MT103 (MEDI-538; bscCD19xCD3), a CD19-specific BiTE that can induc