Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Tanja Eisemann"'
Autor:
Maxwell P. Gold, Winnie Ong, Andrew M. Masteller, David R. Ghasemi, Julie Anne Galindo, Noel R. Park, Nhan C. Huynh, Aneesh Donde, Veronika Pister, Raul A. Saurez, Maria C. Vladoiu, Grace H. Hwang, Tanja Eisemann, Laura K. Donovan, Adam D. Walker, Joseph Benetatos, Christelle Dufour, Livia Garzia, Rosalind A. Segal, Robert J. Wechsler-Reya, Jill P. Mesirov, Andrey Korshunov, Kristian W. Pajtler, Scott L. Pomeroy, Olivier Ayrault, Shawn M. Davidson, Jennifer A. Cotter, Michael D. Taylor, Ernest Fraenkel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Many genes that drive normal cellular development also contribute to oncogenesis. Medulloblastoma (MB) tumors likely arise from neuronal progenitors in the cerebellum, and we hypothesized that the heterogeneity observed in MBs with sonic hed
Externí odkaz:
https://doaj.org/article/7e7b389f322c4aed99ee994b5589418d
Autor:
Menglang Yuan, Iqbal Mahmud, Keisuke Katsushima, Kandarp Joshi, Olivier Saulnier, Rudramani Pokhrel, Bongyong Lee, Wathsala Liyanage, Haritha Kunhiraman, Stacie Stapleton, Ignacio Gonzalez-Gomez, Rangaramanujam M. Kannan, Tanja Eisemann, Elayaraja Kolanthai, Sudipta Seal, Timothy J. Garrett, Saed Abbasi, Kimberly Bockley, Justin Hanes, Prem Chapagain, George Jallo, Robert J. Wechsler-Reya, Michael D. Taylor, Charles G. Eberhart, Animesh Ray, Ranjan J. Perera
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract The prognosis of childhood medulloblastoma (MB) is often poor, and it usually requires aggressive therapy that adversely affects quality of life. microRNA-211 (miR-211) was previously identified as an important regulator of cells that descen
Externí odkaz:
https://doaj.org/article/d02fc40d411f4baba42e490fbec01155
Autor:
Ekaterina L. Ivanova, Barbara Costa, Tanja Eisemann, Sabrina Lohr, Pavle Boskovic, Viktoria Eichwald, Jasmin Meckler, Manfred Jugold, Veronique Orian-Rousseau, Heike Peterziel, Peter Angel
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Glioblastoma multiforme (GBM) is one of the most common and malignant brain tumors in adulthood with a median survival of only 15 months. This poor prognosis is related to GBM’s ability to extensively infiltrate the surrounding brain parenchyma res
Externí odkaz:
https://doaj.org/article/3a278d7ba05a4957a636ec5b29a1a6c1
Autor:
Tanja Eisemann, Barbara Costa, Jens Strelau, Michel Mittelbronn, Peter Angel, Heike Peterziel
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background The poor prognosis for glioblastoma patients is caused by the diffuse infiltrative growth pattern of the tumor. Therefore, the molecular and cellular processes underlying cell migration continue to be a major focus of glioblastoma
Externí odkaz:
https://doaj.org/article/6eed892209b64a2bb22c4cc3ef0f87cc
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The dynamic and interactive tumor microenvironment is conceived as a considerable parameter in tumor development and therapy response. Implementing this knowledge in the development of future cancer treatments could provide novel options in the comba
Externí odkaz:
https://doaj.org/article/cca22be7a83f4794a2d7a8fc8a21da9c
Autor:
Barbara Costa, Michael N. C. Fletcher, Pavle Boskovic, Ekaterina L. Ivanova, Tanja Eisemann, Sabrina Lohr, Lukas Bunse, Martin Löwer, Stefanie Burchard, Andrey Korshunov, Nadia Coltella, Melania Cusimano, Luigi Naldini, Hai-Kun Liu, Michael Platten, Bernhard Radlwimmer, Peter Angel, Heike Peterziel
Publikováno v:
Cancers, Vol 13, Iss 2, p 230 (2021)
Glioblastomas (GBM) are the most aggressive tumors affecting the central nervous system in adults, causing death within, on average, 15 months after diagnosis. Immunocompetent in-vivo models that closely mirror human GBM are urgently needed for decip
Externí odkaz:
https://doaj.org/article/b57bd8c18c9341fb80e356429b46f2b5
Autor:
Kyung-Don Kang, Joshua D. Bernstock, Stacie K. Totsch, Sam E. Gary, Abbey Rocco, Li Nan, Rong Li, Tina Etminan, Xiaosi Han, Elizabeth A. Beierle, Tanja Eisemann, Robert J. Wechsler-Reya, Sejong Bae, Richard Whitley, G. Yancey Gillespie, James M. Markert, Gregory K. Friedman
Publikováno v:
Clin Cancer Res
Purpose: Oncolytic virotherapy with herpes simplex virus-1 (HSV) has shown promise for the treatment of pediatric and adult brain tumors; however, completed and ongoing clinical trials have utilized intratumoral/peritumoral oncolytic HSV (oHSV) inocu
Autor:
Gregory K. Friedman, James M. Markert, G. Yancey Gillespie, Richard Whitley, Sejong Bae, Robert J. Wechsler-Reya, Tanja Eisemann, Elizabeth A. Beierle, Xiaosi Han, Tina Etminan, Rong Li, Li Nan, Abbey Rocco, Sam E. Gary, Stacie K. Totsch, Joshua D. Bernstock, Kyung-Don Kang
Body weights of CBA/J, BALB/c and C57BL/6 mice (N = 5/group) after inoculation with 1x107 PFU of IVT oHSV.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146b772244a5a515361a142123731fa5
https://doi.org/10.1158/1078-0432.22488627
https://doi.org/10.1158/1078-0432.22488627
Autor:
Gregory K. Friedman, James M. Markert, G. Yancey Gillespie, Richard Whitley, Sejong Bae, Robert J. Wechsler-Reya, Tanja Eisemann, Elizabeth A. Beierle, Xiaosi Han, Tina Etminan, Rong Li, Li Nan, Abbey Rocco, Sam E. Gary, Stacie K. Totsch, Joshua D. Bernstock, Kyung-Don Kang
Purpose:Oncolytic virotherapy with herpes simplex virus-1 (HSV) has shown promise for the treatment of pediatric and adult brain tumors; however, completed and ongoing clinical trials have utilized intratumoral/peritumoral oncolytic HSV (oHSV) inocul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7898c5aac2cbf9ca16087b779fbab573
https://doi.org/10.1158/1078-0432.c.6532770.v1
https://doi.org/10.1158/1078-0432.c.6532770.v1
Publikováno v:
Genes & Development. 36:514-532
Medulloblastoma is an aggressive brain tumor that occurs predominantly in children. Despite intensive therapy, many patients die of the disease, and novel therapies are desperately needed. Although immunotherapy has shown promise in many cancers, the