Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Tanja Diemer"'
Autor:
Pin Li, Qin Li, Nilima Biswas, Hong Xin, Tanja Diemer, Lixian Liu, Lorena Perez Gutierrez, Giovanni Paternostro, Carlo Piermarocchi, Sergii Domanskyi, Ruikang K Wang, Napoleone Ferrara
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 1, Pp 1-25 (2021)
Abstract In the course of our studies aiming to discover vascular bed‐specific endothelial cell (EC) mitogens, we identified leukemia inhibitory factor (LIF) as a mitogen for bovine choroidal EC (BCE), although LIF has been mainly characterized as
Externí odkaz:
https://doaj.org/article/097861a25f3d48baa04d343381727fa8
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005882 (2016)
Heterodimers of CLOCK and BMAL1 are the major transcriptional activators of the mammalian circadian clock. Because the paralog NPAS2 can substitute for CLOCK in the suprachiasmatic nucleus (SCN), the master circadian pacemaker, CLOCK-deficient mice m
Externí odkaz:
https://doaj.org/article/0292051cc213461fa07ed2c8e376dcb4
Autor:
Wolfgang H. Dillmann, Anzhi Dai, Jorge Suarez, Federico Cividini, Christopher Benner, Jorge A. Suarez, Darren E. Casteel, Tanja Diemer, Majid Ghassemian, Sven Heinz, Brian T. Scott
Publikováno v:
Diabetes
Diabetes, vol 70, iss 3
Diabetes, vol 70, iss 3
The contribution of altered mitochondrial Ca2+ handling to metabolic and functional defects in type 2 diabetic (T2D) mouse hearts is not well understood. In this study, we show that the T2D heart is metabolically inflexible and almost exclusively dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12a2a47a9b8d9aaa4d67a9af87da90a
https://doi.org/10.2337/db20-0779
https://doi.org/10.2337/db20-0779
Autor:
Carlo Piermarocchi, Hong Xin, Giovanni Paternostro, Lixian Liu, Lorena Perez Gutierrez, Qin Li, Napoleone Ferrara, Pin Li, Sergii Domanskyi, Tanja Diemer, Nilima Biswas, Ruikang K Wang
Publikováno v:
EMBO molecular medicine, vol 14, iss 1
EMBO Molecular Medicine, Vol 14, Iss 1, Pp n/a-n/a (2022)
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 14, Iss 1, Pp n/a-n/a (2022)
EMBO Molecular Medicine
In the course of our studies aiming to discover vascular bed‐specific endothelial cell (EC) mitogens, we identified leukemia inhibitory factor (LIF) as a mitogen for bovine choroidal EC (BCE), although LIF has been mainly characterized as an EC gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaeb4d145e535616adae0b3d9a438283
https://escholarship.org/uc/item/53m7244x
https://escholarship.org/uc/item/53m7244x
Autor:
Wolfgang H Dillmann, Majid Ghassemian, Christopher W Benner, Jorge A Suarez, Tanja Diemer, Anzhi Dai, Sven Heinz, Darren E. Casteel, Jorge Suarez, Brian T Scott, Federico Cividini, Ada Admin
The contribution of altered mitochondrial Ca2+ handling to metabolic and functional defects in type 2 diabetic (T2D) mouse hearts is not well understood. Here, we show that the T2D heart is metabolically inflexible and almost exclusively dependent on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df2a6cba74393b03d680a7ecf6cd09c
https://doi.org/10.2337/figshare.13342229
https://doi.org/10.2337/figshare.13342229
Autor:
Stefanie Volland, Antonio E. Paniagua, Ankita Umapathy, Julian Esteve-Rudd, Roni A. Hazim, Tanja Diemer, David S. Williams
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 21
Stargardt macular dystrophy 3 (STGD3) is caused by dominant mutations in the ELOVL4 gene. Like other macular degenerations, pathogenesis within the retinal pigment epithelium (RPE) appears to contribute to the loss of photoreceptors from the central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6ed739ca534c33e63f672b2ef9b482
https://doi.org/10.1073/pnas.1709211115
https://doi.org/10.1073/pnas.1709211115
Autor:
Jorge Suarez, Wolfgang H. Dillmann, Anzhi Dai, Kim A. Lehmann, Julieta Diaz-Juarez, Tanja Diemer, Mohit Jain, Federico Cividini, Jorge A. Suarez, Brian T. Scott
Publikováno v:
Journal of Biological Chemistry. 293:8182-8195
Diabetes mellitus is a growing health care problem, resulting in significant cardiovascular morbidity and mortality. Diabetes also increases the risk for heart failure (HF) and decreased cardiac myocyte function, which are linked to changes in cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801ded21c004eea46034cfbfeea13d00
https://doi.org/10.1074/jbc.ra118.002066
https://doi.org/10.1074/jbc.ra118.002066
Publikováno v:
Neuroscience. 357:1-11
In mammals, the master circadian clock resides in the suprachiasmatic nucleus (SCN). The SCN is characterized by robust circadian oscillations of clock gene expression and neuronal firing. The synchronization of circadian oscillations among individua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a6e7317c9a767b3898c608fbad4843
https://doi.org/10.1016/j.neuroscience.2017.05.037
https://doi.org/10.1016/j.neuroscience.2017.05.037
Autor:
Tanja Diemer, Federico Cividini, Wolfgang H. Dillmann, Anzhi Dai, Jorge Suarez, Julieta Diaz-Juarez, Brian T. Scott
Diabetic cardiomyopathy is associated with metabolic changes, including decreased glucose oxidation (Gox) and increased fatty acid oxidation (FAox), which result in cardiac energetic deficiency. Diabetic hyperglycemia is a pathophysiological mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c51b072007e6c3882a0e54757acabab
https://europepmc.org/articles/PMC5206303/
https://europepmc.org/articles/PMC5206303/
Autor:
Federico Cividini, Darren E. Casteel, Wolfgang H. Dillmann, Julieta Diaz-Juarez, Brian T. Scott, Jorge Suarez, Wenlong Han, Anzhi Dai, Tanja Diemer
Publikováno v:
The Journal of biological chemistry. 291(51)
mtDNA damage in cardiac myocytes resulting from increased oxidative stress is emerging as an important factor in the pathogenesis of diabetic cardiomyopathy. A prevalent lesion that occurs in mtDNA damage is the formation of 8-hydroxy-2′-deoxyguano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbded34029c2e654ddc53b6326020a2
https://pubmed.ncbi.nlm.nih.gov/27816939
https://pubmed.ncbi.nlm.nih.gov/27816939