Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tanja Butz"'
Autor:
Yong Wang, Anthony S. Prokopowicz, Suresh R. Kapadia, Matt Aaron Tschantz, Maret Panzenbeck, Jonathan Tan, Pla Xiong, John P. Wolak, Xiao-Jun Wang, Susan Pav, Susan Lukas, Scott Jakes, Tina Morwick, Mario G. Cardozo, Usha R. Patel, Tanja Butz, Gregory W. Peet, Hidenori Takahashi, Neil Moss, Robert J. Eckner, Jeffrey D. Peterson, Abdelhakim Hammach, Mohammed A. Kashem, Daniel R. Goldberg, Jessica Huang, Roger J. Snow, Rosemarie Sellati
Publikováno v:
Journal of medicinal chemistry. 46(8)
The tyrosine kinase p56lck (lck) is essential for T cell activation; thus, inhibitors of lck have potential utility as autoimmune agents. Our initial disclosure of a new class of lck inhibitors based on the phenylaminoimidazoisoquinolin-9-one showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83eaf37bb87705b676ad771829aadb77
https://pubmed.ncbi.nlm.nih.gov/12672234
https://pubmed.ncbi.nlm.nih.gov/12672234
Autor:
Hidenori Takahashi, Xiao-Jun Wang, Suresh R. Kapadia, Tina Morwick, Tanja Butz, Roger J. Snow, Matt Aaron Tschantz, Jonathan Tan, Abdelhakim Hammach, Anthony S. Prokopowicz
Publikováno v:
ChemInform. 34
Reaction of 2-chlorobenzonitriles with β-ketoesters in an S N Ar reaction, followed by cyclization in acid provides a versatile route to isoquinolones. Starting from 2,6-dichloro-3-nitrobenzonitrile 7 , sequential displacement of the chlorines by an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898ba2b4311b7b25146a3769d77512fe
https://doi.org/10.1002/chin.200304144
https://doi.org/10.1002/chin.200304144